NAFLD (Non Alcoholic Fatty Liver Disease) Fibrosis Score
Understanding NAFLD (Non Alcoholic Fatty Liver Disease) Fibrosis Score
What is NAFLD (Non Alcoholic Fatty Liver Disease) Fibrosis Score?
NAFLD fibrosis score is the most studied score which has been extensively validated in a large population of patients with Non Alcoholic Fatty Liver disease (NAFLD) for detecting significant fibrosis.. NAFLD is the most common cause of abnormal liver function tests in primary care. It is associated with obesity, insulin resistance, diabetes etc
What does NAFLD (Non Alcoholic Fatty Liver Disease) Fibrosis Score measure?
Contains 5 testsFibrosis Score
Platelet Count
A Platelet Count test measures the average number of platelets in the blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days.
Platelets help stop the bleeding, whenever there is an injury or trauma to a tissue or blood vessel, by adhering and accumulating at the injury site and releasing chemical compounds that stimulate the gathering of more platelets. A loose platelet plug is formed at the site of injury and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps, including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this step, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding.
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