Apolipoproteins A1 & B Serum
Understanding Apolipoproteins A1 & B Serum
What is Apolipoproteins A1 & B Serum?
Apolipoprotein A1 & B are the proteins associated with HDL and LDL respectively. Elevated levels of ApoA1 and decreased level of Apo B is associated with increased risk of cardiovascular disease. This test is ordered by your healthcare practitioner to evaluate your risk of developing cardiovascular disease. These tests are mainly ordered when a person has a personal or family history of heart disease and/or abnormal lipid levels or significantly elevated triglyceride levels. It is also used as a part of regular check up along with lipid profile.
What does Apolipoproteins A1 & B Serum measure?
Contains 3 testsFollowing tests are a part of Apolipoprotein A1 and B serum:
Apolipoprotein A-I (apo A-I) is a protein that plays an important role in the transportation and metabolism of lipids and is the main protein component in high-density lipoprotein. Apo A-I is ordered in someone who has a personal or family history of abnormal lipid levels and/or premature cardiovascular disease. It may be ordered when your doctor is trying to determine the cause of a person's high cholesterol.
Apolipoprotein B/ Apolipoprotein A1 Ratio helps in evaluating your risk of developing cardiovascular disease (CVD); It is also used to monitor treatment for high cholesterol. This test is not widely used for a screening test but may be ordered if a person has a family history of heart disease and/or high cholesterol and triglycerides (hyperlipidemia).
Apolipoprotein B may be measured, along with an apo A-I or other lipid tests, when your doctor is trying to evaluate someone's risk of developing CVD and when a person has a personal or family history of heart disease and/or abnormal lipid levels, especially when the person has significantly elevated triglyceride levels.
Apolipoprotein - B
Apolipoprotein B/A1 Ratio
Apolipoprotein - A1
Interpreting Apolipoproteins A1 & B Serum results
Interpretations
Apolipoprotein A1 is the primary protein associated with HDL Cholesterol. It shows a protective function against heart disease. Increased levels are associated with reduced risk of cardiovascular disease.
Apolipoprotein B is the primary protein associated with LDL Cholesterol and plaque formation. Increased levels are associated with increased risk of heart disease.
The ratio of these two correlates with the risk of cardiovascular disease.