Medcovorin
Medcovorin Products are primarily used for
Harmful effects of methotrexate
About Medcovorin Products
Uses of Medcovorin Products
Calcium Leucovorin is used to prevent harmful effects of methotrexate. It is also used to treat overdose of methotrexate.
Medcovorin Products side effects
Severe
Side Effects of Medcovorin are Nausea, Vomiting, Diarrhea, Anaphylactic reaction, Urticaria, Decreased white blood cell count (lymphocytes), Stomatitis (Inflammation of the mouth), Hair loss, Dermatitis, Decreased appetite.
How Medcovorin Products work
Calcium Leucovorin is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.
Patient Concerns about Medcovorin Products
Frequently asked questions about Medcovorin Products
Frequently asked questions about Calcium Leucovorin
Q. What is Medcovorin Injection used for?
Medcovorin Injection is used to prevent harmful effects of methotrexate (cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Medcovorin Injection is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.
Q. What is megaloblastic anemia?
Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency. How long does it take for Medcovorin Injection to work?
Q. How long does it take for Medcovorin Injection to work?
Medcovorin Injection starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.
Q. What are some of the laboratory tests conducted before or during the treatment with Medcovorin Injection?
Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Medcovorin Injection. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Medcovorin Injection contains calcium.
Q. What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Medcovorin Injection?
Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.
Products for Medcovorin
MRP
₹253
Not Available
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