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Anti-Mullerian Hormone

Also known as Mullerian Inhibiting Hormone (MIH)

₹1535~~₹1850~~ 17% Off

This test is for

Male, Female

Test Preparation

No special preparation required

Understanding Anti-Mullerian Hormone

What is Anti-Mullerian Hormone?

This test measures the level of anti-müllerian hormone (AMH) in the blood. AMH is made in the reproductive tissues of both males and females. It plays an important role in the development of sex organs in an unborn baby. In women, AMH levels can provide information about fertility and the ability to get pregnant. A woman's ovaries can make thousands of eggs during childbearing years. The number declines as a woman gets older. AMH levels help in determining the potential egg cells remaining in a woman's ovaries.

A high level of AMH indicates your chances are better for getting pregnant. High level is also indicative of polycystic ovary syndrome (PCOS). A low level can mean you may have low ovarian reserve and low chances of reproductive success.

What is Anti-Mullerian Hormone used for?

The AMH Test is performed:

· To evaluate the functioning of the ovaries and female fertility (ovarian reserve of eggs) in adult women

· To determine the external sex organs of an infant in case of ambiguous genitalia (a condition where the external sex organs are not clearly distinguishable into male or female)

· To help in the diagnosis of Polycystic Ovarian Syndrome (PCOS)

· To evaluate testicular functioning in infant males

· To monitor treatment efficacy for some ovarian cancers

· To determine the efficacy of assisted reproductive procedures like IVF (In Vitro Fertilisation)

What does Anti-Mullerian Hormone measure?

The AMH Test measures the levels of Anti Mullerian Hormone or AMH in blood.

Anti Mullerian Hormone or AMH is produced primarily by the testicles in males and the ovaries in females. AMH levels in blood determine and regulate a number of activities of the human reproductive system.

In the first few weeks of the fetal development during pregnancy, the fetus has both the primordial male and female reproductive systems and can develop either as a male or a female. In genetic males, high amounts of AMH are secreted by the testicles, suppressing the formation and development of the female reproductive organs from Mullerian ducts (primordial female reproductive system), and encouraging the development of other male sex organs, which results in the development of a male child. Low or no AMH secreted in the genetically female fetus causes the formation and development of female reproductive organs from the Mullerian duct and a female child is developed. Abnormalities of AMH levels in the fetus may cause the formation of ambiguous genitalia.

After birth, AMH levels remain high in males till puberty, after which they fall slowly and taper off with time. AMH levels in females remain low after birth till puberty. During puberty, AMH is secreted by the ovaries resulting in a sharp increase in its levels. The levels slowly keep falling throughout the female reproductive period and become very low to undetectable after menopause. AMH maintains a balance of the two important female reproductive hormones: Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), which regulate the maturation and release of eggs from the ovaries along with other hormones. Hence, AMH levels during the female reproductive period serve as an indication of the ovarian reserve (number of remaining eggs that can mature fully and be released for reproduction), and hence fertility. It is also an indicator of the onset of menopause, especially in older women.
AMH can also be produced by ovarian cysts formed during PCOS, as well as by some types of ovarian tumors.

Interpreting Anti-Mullerian Hormone results

Interpretations

Males:

Age	Blood AMH Level
Below 24 months	14 to 466 ng/ml
24 months to 12 years	7.4 to 243 ng/ml
Above 12 years	0.7 to 19 ng/ml

Females:

Age	Blood AMH Level
Below 24 months	Below 4.7 ng/ml
24 months to 12 years	Below 8.8 ng/ml
13 to 45 years	0.9 to 9.5 ng/ml
Above 45 years	Below 1.0 ng/ml

Results in the normal range indicate high fertility and ovarian reserve and a high chance of IVF success.

Results in the low normal range indicate low fertility and ovarian reserve and a reduced but fair chance of IVF success

Results in the very low range indicate a very low ovarian reserve and low chances of reproductive success with IVF.

High AMH levels are usually seen in PCOS and some AMH producing ovarian tumors.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Anti-Mullerian Hormone

Frequently Asked Questions about Anti-Mullerian Hormone

Q. Is there any risk associated with this test?

There is no risk associated with the test. However, since this test involves a needle prick to withdraw the blood sample, in very rare cases, a patient may experience increased bleeding, hematoma formation (blood collection under the skin), bruising or infection at the site of needle prick.

Q. Is there any preparation required before the AMH test?

Since AMH levels in blood remain fairly consistent and do not vary like other hormones through the menstrual cycle, this test may be performed any time. However, birth control pills may affect the AMH levels, hence if you are on birth control pills, it is advisable to discontinue them about 1 to 2 months before the test is performed. Inform the doctor of any medications you may be taking. No other specific preparations are usually required before the AMH Test.

Q. What factors can affect the AMH test results?

The AMH levels in blood can be affected by a number of factors including: · Age of the patient · Heavy smoking · Stress · Hormonal imbalance · Illness · Chronic exposure to environmental smoke · Chemotherapy drugs

Q. What additional tests can be prescribed by your doctor in case of abnormal AMH test result?

Additional tests that may be prescribed in case of abnormal AMH test result are: · Androgen (Testosterone) Test · Estrogen and Progesterone Tests · FSH and LH Tests · Inhibin B Test for fertility · Inhibin Test (A and B) for tumour workup

Q. What is IVF?

IVF or In Vitro Fertilisation is a type of Assisted Reproductive Technology (ART) where eggs retrieved from the female and sperms retrieved from the male are made to fuse and undergo fertilization in a laboratory, instead of the female body. The zygote formed is incubated for some time and is then implanted into the female uterus for further development and delivery. It is a commonly used procedure to overcome the inability to conceive and complete pregnancy naturally.

Q. What is PCOS?

Polycystic Ovarian Syndrome or PCOS refers to a group of medical conditions in females caused due to high levels of male hormones or androgens. It is usually characterized by the presence of multiple cysts on the ovaries in affected females. Symptoms of PCOS include: · Irregular or no menstruation · Abnormal bleeding during periods · Excessive male pattern body hair on face, chest, and buttocks (hirsutism) · Thinning of hair and hair loss from head · Patches of skin turning velvety black (acanthosis nigricans) · Acne · Loss of fertility The condition is usually associated with obesity and diabetes and may give rise to severe complications if not managed, including high blood cholesterol causing cardiovascular disorders, sleep apnea, infertility, depression, endometrial cancer, etc.

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