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MMST, MBBS
Reviewed By
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Tretin-Iso 10 Capsule


Product introduction

Tretin-Iso 10 Capsule belongs to a group of medicines called retinoids (vitamin A derivative). It is used to treat severe acne that has not responded to other treatments.

Tretin-Iso 10 Capsule is used to treat red pimples on the skin

Uses of Tretin-Iso Capsule

Benefits of Tretin-Iso Capsule

In Treatment of Acne

Tretin-Iso 10 Capsule helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Tretin-Iso Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tretin-Iso

  • Dry skin
  • Increased liver enzymes
  • Rash

How to use Tretin-Iso Capsule

Take this medicine in the dose and duration as advised by your doctor. Tretin-Iso 10 Capsule is to be taken with food.

How Tretin-Iso Capsule works

Tretin-Iso 10 Capsule is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Tretin-Iso 10 Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Tretin-Iso 10 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Tretin-Iso 10 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Tretin-Iso 10 Capsule may cause side effects which could affect your ability to drive.
Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability.
Kidney
CAUTION
Tretin-Iso 10 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Tretin-Iso 10 Capsule may be needed. Please consult your doctor.
Liver
UNSAFE
Tretin-Iso 10 Capsule is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips

  • You have been prescribed Tretin-Iso 10 Capsule for the treatment of severe acne.
  • Take it with food.
  • Avoid exposure to sunlight while using Tretin-Iso 10 Capsule. Use protective measures such as sunscreen or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.
  • Do not take Tretin-Iso 10 Capsule if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Retinoid
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Retinoids- First generation

Patient concerns

arrow
sir, i have acne problem on my back and face . can i take tretin iso , tretin 0.025 cream and divaine 50 and this problem for 5 yrs running
Dr. Banashree Majumdar
Dermatology
Dear PATIENT can understand your problem, but you need to understand that getting acne at this age is common, you should not use any product from outside particularly the oily one. Apply Clindac A gel twice daily and Cetaphil cleansing lotion for oily skin.
Left right shoulder to arm pain in about 3month's
Dr. Akshat Goel
Orthopaedics
Do Iso-metric cervical exercises(Consult a physiotherapist for the same) Avoid forward bending take Tab Meganeuron-PG and Tab Myospas-D twice daily
arrow

User feedback


FAQs

Is Tretin-Iso 10 Capsule safe to use?

Tretin-Iso 10 Capsule should be used with care since it is associated with significant adverse reactions. It should be used only for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Tretin-Iso 10 Capsule should not be used by pregnant women because it can cause severe birth defects.

Is Tretin-Iso 10 Capsule a steroid?

No, Tretin-Iso 10 Capsule is a retinoid (vitamin A) which is used to treat severe types of acne.

What are the recommended tests during Tretin-Iso 10 Capsule therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at 3 monthly intervals unless more frequent monitoring is clinically indicated.

Is the effect of Tretin-Iso 10 Capsule permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Tretin-Iso 10 Capsule has shown that the symptoms in the patients with acne may continue to improve following treatment with Tretin-Iso 10 Capsule.

Why is Tretin-Iso 10 Capsule so dangerous during pregnancy?

If pregnancy occurs during treatment with Tretin-Iso 10 Capsule then, there is an extremely high risk that the baby may be born with severe birth defects.

Can Tretin-Iso 10 Capsule cause cancer?

No, there are no reports of Tretin-Iso 10 Capsule causing cancer. In fact, it may be useful in some forms of head, skin, and neck cancers.

What are the long-term side effects of Tretin-Iso 10 Capsule?

A normal course of treatment of Tretin-Iso 10 Capsule is 15–20 weeks. Therefore, the long-term effects of low doses have not been studied. However, it may have some effect on bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Does Tretin-Iso 10 Capsule affect male fertility?

No, Tretin-Iso 10 Capsule does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology, or seminal plasma fructose.

Does Tretin-Iso 10 Capsule damage your liver?

There may be a transient increase in liver enzymes with Tretin-Iso 10 Capsule use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Tretin-Iso 10 Capsule.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.
  2. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.
  3. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.
  5. Isotretinoin. Nutley, New Jersey: Roche Laboratories Inc.; 2002. [Accessed on 2 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organization. Safety guidelines for isotretinoin. 2018. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  8. CiplaMed. Isotretinoin [Prescribing Information]. [Last Revised: 29 Nov. 2019]. [Accessed 05 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Hegde and Hegde Pharmaceutical LLP
Address: Office No. 11A – 15, 1st Floor, Free Press House, 215, Nariman Point, Mumbai – 400 021
Country of origin: India

MRP
165
Inclusive of all taxes
10.0 capsules in 1 strip
SOLD OUT

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