Isotretinoin

Information about Isotretinoin

Isotretinoin Uses

Isotretinoin is used in the treatment of acne.

How Isotretinoin works

Isotretinoin is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Common side effects of Isotretinoin

Dry skin, Dry eye, Dermatitis, Dry lips, Nosebleeds, Back pain, Joint pain, Headache, Nasopharyngitis (inflammation of the throat and nasal passages), Increased creatine phosphokinase level in blood, Lip inflammation, Reduced visual acuity
CONTENT DETAILS
Written By
Dr. Anuj Saini 2
MMST, MBBS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Last updated
13 Jun 2023 | 11:29 AM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Isotretinoin

AcnestarMankind Pharma Ltd
₹80 to ₹1295 variant(s)
SotretSun Pharmaceutical Industries Ltd
₹82 to ₹3297 variant(s)
IsotroinCipla Ltd
₹94 to ₹4487 variant(s)
TretivaIntas Pharmaceuticals Ltd
₹85 to ₹3426 variant(s)
AcutretIpca Laboratories Ltd
₹103 to ₹3414 variant(s)
Tretin-IsoHegde and Hegde Pharmaceutical LLP
₹165 to ₹2452 variant(s)
IsotaneMicro Labs Ltd
₹75 to ₹2853 variant(s)
D Acne IGlenmark Pharmaceuticals Ltd
₹153 to ₹2602 variant(s)
IsoinWallace Pharmaceuticals Pvt Ltd
₹183 to ₹2962 variant(s)
TufacneAbbott L
₹169 to ₹2792 variant(s)

Expert advice for Isotretinoin

  • You have been prescribed Isotretinoin for the treatment of severe acne.
  • Take it with food.
  • Avoid exposure to sunlight while using Isotretinoin. Use protective measures such as sun-cream or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Avoid taking tetracycline as it may reduce the Isotretinoin activity.
  • Do not take Isotretinoin if you are pregnant, planning pregnancy or breastfeeding.
  • It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.

Frequently asked questions for Isotretinoin

Isotretinoin

Q. Is Isotretinoin safe to use?

Isotretinoin should be used with caution since it is associated with significant adverse reactions. It should be used only by patients who have severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. In addition, Isotretinoin should not be used by pregnant women because it can cause severe birth defects.

Q. Is Isotretinoin a steroid?

No, Isotretinoin is a retinoid (vitamin A) which is used to treat severe types of acne.

Q. What are the recommended tests during Isotretinoin therapy?

Your liver enzymes and serum lipids will be checked before the treatment is started. These levels will also be monitored 1 month after the start of treatment and subsequently at an interval of 3 months unless more frequent monitoring is clinically indicated.

Q. Is the effect of Isotretinoin permanent?

It has been observed in many patients that a single 15-20-week course effectively cures the condition and prevents it from coming back. If at all a second course is required, one should wait for at least 8 weeks after completion of the first course. This is because experience with Isotretinoin has shown that the symptoms in the patients with acne may continue to improve following treatment with Isotretinoin.

Q. Why is Isotretinoin so dangerous during pregnancy?

If pregnancy occurs during treatment with Isotretinoin, then there is an extremely high risk that the baby may be born with severe birth defects.

Q. Can Isotretinoin cause cancer?

No, there are no reports of Isotretinoin causing cancer. In fact, it may be useful in some forms of head, skin and neck cancers.

Q. What are the long-term side effects of Isotretinoin?

A normal course of treatment of Isotretinoin is 15–20 weeks. Therefore, long-term effects of low doses have not been studied. However, it may have some effect on the bone mineral density. It may decrease bone mineral density in some patients, resulting in osteoporosis or fractures.

Q. Does Isotretinoin affect male fertility?

No, Isotretinoin does not affect the fertility of male patients. No significant effects were seen on ejaculate volume, sperm count, total sperm motility, morphology or seminal plasma fructose.

Q. Does Isotretinoin damage your liver?

There may be a transient increase in liver enzymes with Isotretinoin use. Therefore, regular laboratory tests are required. These values generally return to normal after some time. If the levels remain elevated for a long time, your doctor may discontinue the use of Isotretinoin.

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App

Connect

  • Social Links
  • Want daily dose of health?
Download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

© 2024 Tata 1mg. All rights reserved. All medicines are dispensed in compliance with the Drugs and Cosmetics Act, 1940 and Drugs and Cosmetics Rules, 1945. We do not process requests for Schedule X and habit forming drugs.