Sirova 1mg Tablet
Prescription Required
Product introduction
Sirova 1mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.
Sirova 1mg Tablet is used to prevent the body rejecting the organ that is transplanted and also to prevent cancer post organ transplant
Sirova 1mg Tablet is used to prevent the body rejecting the organ that is transplanted and also to prevent cancer post organ transplant
Uses of Sirova Tablet
- Prevention of kidney transplant rejection
Benefits of Sirova Tablet
In Prevention of kidney transplant rejection
Sirova 1mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Sirova Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sirova
- Nausea
- Increased blood lipid level
- Low blood platelets
- Headache
- Abdominal pain
- Fever
- Anemia (low number of red blood cells)
- Urinary tract infection
- Diarrhea
- High blood pressure
- Increased creatinine level in blood
- Joint pain
- Edema (swelling)
How to use Sirova Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sirova 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sirova 1mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sirova 1mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Sirova 1mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Sirova 1mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Sirova 1mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sirova 1mg Tablet is recommended.
Liver
CAUTION
Sirova 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Sirova 1mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
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Quick tips
- Sirova 1mg Tablet is used to prevent organ rejection following a kidney transplant operation.
- Avoid grapefruit juice while you are on treatment with this medicine. This is because a chemical in grapefruit juice increases the amount of Sirova 1mg Tablet in your bloodstream. This makes side-effects more likely.
- There is a possibility of a slight increase in the risk of skin cancer with Sirova 1mg Tablet. Do not use sunbeds, and avoid strong sunlight or use a sun cream with a high sun protection factor (SPF of at least 15).
- If you have diabetes mellitus, this medicine may affect your blood sugar levels. Monitor your sugar level regularly and report any extreme changes to your doctor.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- mTOR inhibitors
Patient concerns
User feedback
Patients taking Sirova 1mg Tablet
Once A Day
86%
Twice A Day
14%
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1012-13.
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 972-73.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1267-68.
- Drugs.com. Sirolimus. [Accessed 06 Apr. 2019] (online) Available from:
- Sirolimus. Sandwich, Kent: Pfizer Limited; 2001 [revised Oct. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
- Sirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc; 1999. [Accessed 06 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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