Information about Sirolimus

Sirolimus Uses

Sirolimus is used for prevention of kidney transplant rejection.

How Sirolimus works

Sirolimus is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Common side effects of Sirolimus

Nausea1a, Vomiting, Upset stomach, Protein in urine, Decreased blood cells (red cells, white cells, and platelets), Mouth ulcer, Increased risk of infection
CONTENT DETAILS
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
22 Feb 2021 | 11:18 AM (UTC)

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Available Medicine for Sirolimus

SiromusZydus Cadila
10411 variant(s)
SiropanPanacea Biotec Pharma Ltd
23031 variant(s)
RocasEmcure Pharmaceuticals Ltd
7681 variant(s)
RapacanBiocon
2296 to ₹25902 variant(s)
SirovaIntas Pharmaceuticals Ltd
15021 variant(s)
RaparenLa Renon Healthcare Pvt Ltd
1499 to ₹15742 variant(s)
LimusClaris Lifesciences Ltd
13651 variant(s)
SirotrendAnthem Biopharma
15001 variant(s)
RapolaxTaj Pharma India Ltd
12711 variant(s)
ToraftTorrent Pharmaceuticals Ltd
15701 variant(s)

Expert advice for Sirolimus

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.

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