Linamac 25 Capsule
Prescription Required
Product introduction
Linamac 25 Capsule belongs to a group of medicines that affect how your immune system works. $It is used in the treatment of multiple myeloma and myelodysplastic syndrome.
Linamac 25 Capsule is used in the treatment of many different blood and bone marrow diseases including some cancers.
Linamac 25 Capsule is used in the treatment of many different blood and bone marrow diseases including some cancers.
Uses of Linamac Capsule
Benefits of Linamac Capsule
In Treatment of Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Linamac 25 Capsule may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
In Treatment of Myelodysplastic syndrome
Myelodysplastic Syndromes (MDS) are a group of rare blood disorders characterized by abnormal development of blood cells in the bone marrow. In MDS, the bone marrow fails to produce enough healthy and fully matured blood cells, leading to low blood cell counts, which can result in anemia, infections, and bleeding problems.
Linamac 25 Capsule is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Linamac 25 Capsule helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Linamac 25 Capsule is used to treat certain types of MDS, specifically those associated with a specific part of the chromosomes in the blood cells. It works by helping the immune system make more healthy blood cells in the bone marrow. Linamac 25 Capsule helps improve the production of red blood cells, reducing the need for frequent blood transfusions and making them feel better. It is important to check-up and monitor regularly to make sure it is safe and effective.
Side effects of Linamac Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Linamac
- Headache
- Nausea
- Rash
- Breathlessness
- Dizziness
- Fatigue
- Decreased white blood cell count (neutrophils)
- Joint pain
- Itching
- Diarrhea
- Low blood platelets
- Peripheral edema
- Cough
- Back pain
- Upper respiratory tract infection
- Decreased appetite
- Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Linamac Capsule
Take this medicine in the dose and duration as advised by your doctor. Linamac 25 Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Linamac Capsule works
Linamac 25 Capsule is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Linamac 25 Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Linamac 25 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Linamac 25 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Linamac 25 Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Linamac 25 Capsule and this may affect your ability to drive.
You may feel dizzy, tired, sleepy, have vertigo or blurred vision after taking Linamac 25 Capsule and this may affect your ability to drive.
Kidney
CAUTION
Linamac 25 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Linamac 25 Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Linamac 25 Capsule should be used with caution in patients with liver disease. Dose adjustment of Linamac 25 Capsule may be needed. Please consult your doctor.
What if you forget to take Linamac Capsule?
If you miss a dose of Linamac 25 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Linamac 25 Capsule
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Celomide 25 Capsule
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Lenalid 25 Capsule
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Quick tips
- You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
- Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
- It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
- It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
- It is not recommended for use in children and adolescents under 18 years.
- You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
- Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
- You should inform your doctor or dentist that you are taking Linamac 25 Capsule before you receive any medical or dental care, emergency care, or surgery.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Linamac 25 Capsule. You should discuss in advance the benefits and risks of taking this medicine.
Fact Box
Chemical Class
Phthalimide and Piperidone Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Thalidomide & its Immunomodulatory derivatives (IMiDs)
Patient concerns
FAQs
Can I take Linamac 25 Capsule empty stomach?
Linamac 25 Capsule may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Linamac 25 Capsule at about the same time on the scheduled days.
Can Linamac 25 Capsule be given to patients who are on dialysis?
Yes, Linamac 25 Capsule is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.
What are the side effects of Linamac 25 Capsule?
Linamac 25 Capsule may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.
Can Linamac 25 Capsule cause cancer?
People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Linamac 25 Capsule have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Linamac 25 Capsule.
Do I need to get any blood tests done while on Linamac 25 Capsule?
Your doctor will ask you to have a blood test before treatment and every week for the first 8 weeks of treatment. You may need to continue taking the blood tests at least every month after treatment with Linamac 25 Capsule ends. Frequent blood tests are important as Linamac 25 Capsule may decrease the blood cells that help fight infection (white blood cells) and help the blood to clot (platelets).
Do I need to use birth control methods while using Linamac 25 Capsule?
Women who can become pregnant must use two acceptable forms of birth control for 4 weeks before they begin taking Linamac 25 Capsule. Continue using contraceptives during your treatment, including the times when your doctor tells you to temporarily stop taking Linamac 25 Capsule, and for 4 weeks after your final dose. In men, Linamac 25 Capsule may pass into the semen while they are on treatment. Therefore, men must always use a latex condom every time they have sexual contact, even if they have had a vasectomy (surgery that prevents a man from causing a pregnancy). Use the contraceptive while you are taking Linamac 25 Capsule, during any breaks in your treatment, and for 4 weeks after your final dose.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.
- Lenalidomide. Summit, New Jersey: Celgene Corporation. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
- LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012. Lenalidomide. [Updated 2022 Aug 30]. [Accessed 08 Jul. 2023]. (online) Available from:
- Lenalidomide Capsules [Package Insert]. Bangalore, India: Biocon Limited. [Accessed 08 Jul. 2023]. (online) Available from:
- Lenalidomide [Prescribing Information]. Nantou City, Taiwan: Lotus Pharmaceutical Co., Ltd.; 2022. [Accessed 08 Jul. 2023]. (online) Available from:
Marketer details
Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.
Country of origin: India
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MRP
₹6873
Inclusive of all taxes
21.0 capsules in 1 bottle
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