Glura M XR 1000 Tablet
Prescription Required
Introduction of Glura M Tablet ER
Glura M XR 1000 Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.
Glura M XR 1000 Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.
Glura M XR 1000 Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.
Uses of Glura M Tablet ER
Benefits of Glura M Tablet ER
In Treatment of Type 2 diabetes mellitus
Glura M XR 1000 Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.
Side effects of Glura M Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Glura M
- Hypoglycemia (low blood glucose level)
- Nausea
- Vomiting
- Diarrhea
- Decreased appetite
- Abdominal bloating
- Upper respiratory tract infection
How to use Glura M Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glura M XR 1000 Tablet is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Glura M XR 1000 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Glura M XR 1000 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Glura M XR 1000 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Glura M XR 1000 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glura M XR 1000 Tablet may be needed. Please consult your doctor.
Use of Glura M XR 1000 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Use of Glura M XR 1000 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
UNSAFE
Glura M XR 1000 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Glura M Tablet ER?
If you miss a dose of Glura M XR 1000 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Glura M XR 1000 Tablet
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Quick tips
Glura M Tablet ER
- You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
- Take it with food to lower your chance of having an upset stomach.
- Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Monitor your blood sugar level regularly while you are taking this medicine.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Glura M XR 1000 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
Patient concerns
FAQs
Glura M Tablet ER
What is Glura M XR 1000 Tablet?
Glura M XR 1000 Tablet is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.
Can the use of Glura M XR 1000 Tablet lead to Vitamin B12 deficiency?
Yes, the use of Glura M XR 1000 Tablet can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
What are the possible side effects of Glura M XR 1000 Tablet?
The use of Glura M XR 1000 Tablet is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
Are there any specific conditions in which Glura M XR 1000 Tablet should not to be taken?
The use of Glura M XR 1000 Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.
Is it safe to take alcohol while I am taking Glura M XR 1000 Tablet?
No, it is not safe to alcohol along with Glura M XR 1000 Tablet, as it can increase the chances of lactic acidosis.
What are the instructions for storage and disposal of Glura M XR 1000 Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can the use of Glura M XR 1000 Tablet lead to lactic acidosis?
Yes, the use of Glura M XR 1000 Tablet can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sitagliptin/metformin hydrochloride. Haarlem, The Netherlands: Merck Sharp & Dohme BV; 2018. [Accessed 08 Apr. 2019] (online) Available from:
- Sitagliptin / metformin hydrochloride. London, UK: European Medicine Agency; 2013. [Accessed 08 Apr. 2019] (online) Available from:
- Mayo Clinic. Sitagliptin and Metformin. [Accessed 08 Apr. 2019 ] (online) Available from:
- Sitagliptin and metformin hydrochloride. [Accessed 08 Apr. 2019] (online) Available from:
- Sitagliptin and Metformin hydrochloride [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2021. [Accessed 20 Oct. 2021] (online) Available from:
- Sitagliptin and Metformin hydrochloride [Product Monograph]. Kirkland, Canada: Merck Canada Inc.; 2017. [Accessed 20 Oct. 2021] (online) Available from:
Marketer details
Name: Eris Lifesciences Ltd
Address: 8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India
Country of origin: India
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