Sitagliptin + Metformin

Information about Sitagliptin + Metformin

Sitagliptin + Metformin Uses

Sitagliptin + Metformin is used in the treatment of type 2 diabetes mellitus. It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How Sitagliptin + Metformin works

Sitagliptin + Metformin is a combination of two antidiabetic medicines: Sitagliptin and Metformin. They help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Together, they provide better control of blood sugar.

Common side effects of Sitagliptin + Metformin

Diarrhea, Nausea1a, Vomiting, Upset stomach, Headache, Nasal congestion (stuffy nose), Sore throat, Respiratory tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
CONTENT DETAILS
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
20 Sep 2021 | 03:26 PM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Sitagliptin + Metformin

IstametSun Pharmaceutical Industries Ltd
135 to ₹4167 variant(s)
JanumetMSD Pharmaceuticals Pvt Ltd
334 to ₹4154 variant(s)
SiglimepolMedipol Pharmaceuticals India Pvt Ltd
3911 variant(s)
217 to ₹2973 variant(s)
Ctasorin MFusion Healthcare Pvt Ltd
140 to ₹1904 variant(s)
Emsita MEmcure Pharmaceuticals Ltd
159 to ₹1692 variant(s)
Ignalis-MIntas Pharmaceuticals Ltd
95 to ₹1495 variant(s)
KrezsitaKrezlin Pharma
69 to ₹994 variant(s)
Sitormin MXenon Pharmaceuticals
313 to ₹3352 variant(s)
Sepamet-XRTaj Pharma India Ltd
245 to ₹6583 variant(s)

Expert advice for Sitagliptin + Metformin

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it with food to lower your chance of having an upset stomach.
  • Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Sitagliptin + Metformin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Frequently asked questions for Sitagliptin + Metformin

Sitagliptin + Metformin

Q. What is Sitagliptin + Metformin?

Sitagliptin + Metformin is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.

Q. What are the possible side effects of Sitagliptin + Metformin?

The use of Sitagliptin + Metformin is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.

Q. Are there any specific conditions in which Sitagliptin + Metformin should not to be taken?

The use of Sitagliptin + Metformin should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am taking Sitagliptin + Metformin?

No, it is not safe to alcohol along with Sitagliptin + Metformin, as it can increase the chances of lactic acidosis.

Q. Can the use of Sitagliptin + Metformin lead to lactic acidosis?

Yes, the use of Sitagliptin + Metformin can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

Q. Can the use of Sitagliptin + Metformin lead to Vitamin B12 deficiency?

Yes, the use of Sitagliptin + Metformin can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. What are the instructions for storage and disposal of Sitagliptin + Metformin?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.