Epotrend 4000 Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV.

Epotrend 4000 Injection is used to treat anemia (deficiency of red blood cells in blood)

Uses of Epotrend Injection

Benefits of Epotrend Injection

In Treatment of Anemia due to chronic kidney disease

Epotrend 4000 Injection is a man-made protein that helps your bone marrow to produce more red blood cells. It is used to treat anemia which is caused by kidney disease in adults and children who are on dialysis. Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. This medicine helps reduce weakness and tiredness that you may be experiencing due to anemia. The injection is usually given by a doctor after a dialysis treatment.

In Treatment of Anemia due to cancer chemotherapy

Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epotrend 4000 Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.

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Side effects of Epotrend Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epotrend

High blood pressure
Nausea
Vomiting
Fever
Rash
Joint pain
Headache
Insomnia (difficulty in sleeping)
Chills
Cough
Bone pain
Muscle spasm
Dizziness
Vascular occlusion
Injection site irritation
Stomatitis (Inflammation of the mouth)
Weight loss
Decreased white blood cell count (lymphocytes)
Increased glucose level in blood
Blood clot in the blood vessels

How to use Epotrend Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Epotrend 4000 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Epotrend 4000 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Epotrend 4000 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Epotrend 4000 Injection may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Epotrend 4000 Injection is safe to use in patients with kidney disease. No dose adjustment of Epotrend 4000 Injection is recommended.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.

Liver

CAUTION

Epotrend 4000 Injection should be used with caution in patients with liver disease. Dose adjustment of Epotrend 4000 Injection may be needed. Please consult your doctor.

What if you forget to take Epotrend Injection?

If you miss a dose of Epotrend 4000 Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Epotrend 4000 Injection

₹1600.0/Injection

Vintor 4000 Injection

Emcure Pharmaceuticals Ltd

₹963.8/injection

40% cheaper

Eporise 4000 Injection

Zuventus Healthcare Ltd

₹1194/injection

25% cheaper

Anfoe 4000IU Injection

La Renon Healthcare Pvt Ltd

₹1299/injection

19% cheaper

Renocel 4000IU Injection

Intas Pharmaceuticals Ltd

₹1480/injection

8% cheaper

Repoitin 4000 Injection

Serum Institute Of India Ltd

₹1197.89/injection

25% cheaper

View all substitutes

Quick tips

Epotrend 4000 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
Stop taking Epotrend 4000 Injection and inform your doctor if you develop shortness of breath or skin rash.

Fact Box

Chemical Class

Amino Acids, Peptides Analogues

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Erythropoiesis-stimulating agent (ESA)

Patient concerns

Blood Hb is found 5.9 so wat is it

Dr. Ila Jain Khandelwal

Pathology

Dear PATIENT from 1mg. The hemoglobin is very low, which can be due to anemia. I suggest you should consult a Hematologist /Physician for this.

how to resolve the problem of anemia?

Dr. Rekha Pohani

Dietetics/Nutrition

Intake of dates and jaggery will help

Weight loss is a challenge despite active lifestyle. Water retention. One kidney not functional. Anemia, hb 9.2.

Shikha Mishra

Dietetics/Nutrition

eat 6-7 meals per day, which consist fruits, nuts, buttermilk,sprouts,idly,curd eggs,sprouts homecooked food. Drink 3-4 litters of water limit your sugar consumption to 2 spoon per day. Be active whole day for personalized diet chart write to me on [email protected] do minimum 45 min exercise everyday like yoga, cardioare u taking treatment for kidney, if yes then consult dietician where u are going for treatment because it should be planned under doctor's guidance

User feedback

Patients taking Epotrend 4000 Injection

Twice A Week

50%

Once A Week

37%

Once A Day

10%

Once A Month

Thrice A week

What are you using Epotrend Injection for?

Anemia due to*

100%

*Anemia due to chronic kidney disease

How much was the improvement?

Excellent

50%

Poor

33%

Average

17%

What were the side-effects while using Epotrend 4000 Injection?

No Side Effec*

100%

*No Side Effect

FAQs

How should Epotrend 4000 Injection be stored?

In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8 ℃. If you are using this medicine at home, it is important that the pre-filled syringe is stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Epotrend 4000 Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.

What to do if you use too much Epotrend 4000 Injection?

Tell the doctor or nurse immediately if you think too much Epotrend 4000 Injection has been injected.

When should Epotrend 4000 Injection not be used?

Epotrend 4000 Injection should not be used if the solution is clouded or you can see particles floating in it or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.

Can Epotrend 4000 Injection be used in children?

Yes, Epotrend 4000 Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Epotrend 4000 Injection and side effects seen in children are similar to adults.

Can Epotrend 4000 Injection affect blood pressure?

Yes, Epotrend 4000 Injection can affect blood pressure. During initial therapy with Epotrend 4000 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Epotrend 4000 Injection if the blood pressure remains uncontrolled.

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Complete Blood Count

Peripheral Smear Examination

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

ScienceDirect. Recombinant Human Erythropoietin Alfa/Epoetin Alfa. [Accessed 07 Apr. 2019] (online) Available from:
Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Leiden, Netherlands: Janssen Biologics B.V; [revised Oct. 2018]. [Accessed 07 Apr. 2019] (online) Available from:
Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Amgen Inc; 1989 [revised Dec. 2013]. [Accessed 07 Apr. 2019] (online) Available from:

Marketer details

Name: Anthem Biopharma

Address: No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.

Country of origin: India

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MRP

₹1600

Inclusive of all taxes

1.0 ml in 1 prefilled syringe

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