Zyla Vitamin Package
Understanding Zyla Vitamin Package
What is Zyla Vitamin Package?
Zyla vitamin package is an elaborate package consisting of various tests that assess your overall health. This package not only measures levels of certain vitamins but also keeps a check on your overall health by evaluating parameters of liver, kidney, blood, and urine.
What does Zyla Vitamin Package measure?
Contains 71 testsFollowing tests are a part of the Zyla Vitamin package:
A kidney panel is a group of blood tests, which is used to determine how well the kidneys are working. KFT is performed either as a part of routine health checkups or to help diagnose any disease affecting the kidneys. It can also screen people at risk for the development of any kidney disease and even monitor the treatment efficacy of kidney diseases.
Glucose fasting blood test determines the normal fasting blood glucose levels in your blood. This test evaluates whether your blood glucose is in a healthy range or not. A value more or less than the reference range indicates high and low blood sugar levels.
Vitamin B12 test is also done if you have symptoms of anemia like weakness, tiredness, pale skin (deficiency of B12), or folic acid deficiency. This is also a preferred test if you have symptoms or signs of nerve problems like numbness, burning in hands, feet, arms, tingling sensation which may be due to vitamin B12 deficiency.
HbA1c or glycosylated hemoglobin test acts as an important guide in diagnosing and monitoring your diabetes. Hemoglobin, a protein found in your red blood cells, carries oxygen from the lungs to the rest of the body, and glucose present in our body tends to attach to this protein. This action can provide information regarding the fluctuations in blood sugar levels. HbA1c measures average blood glucose of the past two to three months (the average lifespan of a red blood cell is 120 days).
A urine microalbumin test detects minute levels of a blood protein (albumin) in your urine. A microalbumin test is used to detect early signs of kidney damage in people who are at high risk of developing kidney disease. This test is ordered by people with an increased risk of kidney diseases, such as those with high blood pressure or diabetes.
EGFR or estimated glomerular filtration rate test measures kidney function. It can help determine any underlying chronic kidney disease. This test is ordered when there is:
Swelling or puffiness, especially around the eyes or in the face, ankles, thighs, or abdomen.
Bloody, foamy, or coffee-colored urine
Significant reduction in the amount of urine
Burning feeling or abnormal discharge during urination, or a change in the frequency of urination, particularly at night
Pain below the ribs or mid-back pain (location close to the kidneys)
Iron studies is ordered when either deficiency of iron or excess of iron is suspected in your body. The symptoms of iron deficiency are pale skin, fatigue, headaches, weakness. This test is ordered if you have signs or symptoms of iron deficiency anemia like fatigue, weakness, headaches or your CBC shows that your hemoglobin and hematocrit are low and RBCs are smaller and paler indicating iron deficiency anemia. These tests can even be done if you have signs or symptoms of increased accumulation of iron in the body like joint pain, abdominal pain, fatigue, loss of body hair.
Vitamin D (25-OH) is done if you face symptoms of vitamin D deficiency like bone malformation in children (rickets), bone weakness, or fractures in adults (osteomalacia), or any risk factors for vitamin D deficiency like old age, limited sun exposure, obesity, or recent gastric bypass surgery.
Urine routine and microscopy test is done to detect problems that show up in your urine. Various diseases and disorders of the body affect the way toxins and wastes are removed from your body. Your kidneys, bladder, and urinary tract are amongst the major organs involved in removing toxins from your body.
Erythrocyte sedimentation rate (ESR) measures the rate of sedimentation of erythrocytes (red blood cells) or how quickly they settle at the bottom of a test tube containing a blood sample. Usually, red blood cells settle relatively slowly. A faster-than-normal rate shows inflammation in the body, which could be a result of an infection or injury. Inflammation may also be a sign of an immune disorder, chronic disease, or any other medical condition like arthritis, inflammatory bowel disease, or vasculitis.
Liver function test is used to assess the function of the liver and is done when any liver disease like viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, and cirrhosis (scarring of the liver) is suspected. This test is also done for monitoring of any ongoing treatment or simply as a part of a routine checkup.
Complete blood count (CBC) is a group of tests that provides information about your blood group and blood cells like Red Blood Cells (RBC), White Blood Cells (WBC), and platelets. It is routinely performed to provide an overview of a patient's general health status. it is also helpful in detecting a variety of disorders including infections, anemia, diseases of the immune system, and blood cancers and is done to monitor an existing blood disorder and its treatment such as chemotherapy or radiotherapy.
Thyroid profile total is a group of tests that are performed to detect or diagnose any fluctuation of thyroid levels in the body. It basically provides information about three hormones present in the blood: Thyroid Stimulating Hormone (TSH), Thyroxine (T4) - Total and TriIodothyronine (T3) - Total. This test helps to diagnose any suspected thyroid disease (Hypothyroidism or Hyperthyroidism). It also helps to monitor the progress of treatment in patients with thyroid diseases.
Lipid profile is a group of blood tests that detects the levels of different types of lipids present in the blood. A lipid profile measures cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides. It is done to screen for the risk of cardiovascular disease and to monitor patients who have risk factors for cardiovascular diseases.
Vitamin B12
Vitamin B12 is a part of B complex of vitamins. Vitamin B12 is also called as Cobalamin. It is a water soluble vitamin. Vitamin B12 plays an important role in formation of normal red blood cells, repair of tissues, DNA synthesis and genetic material in cells. It is not produced in the body and has to be taken in diet. The diet sources include red meat, fish, milk, poultry, yoghurt, eggs, fortified cereals, breads and other grain products. It can also be taken in the form of Vitamin B12 tablets or multivitamin pills. The deficiency of Vitamin B12 results in macrocytic anemia (size of red blood cells larger than normal).
Megaloblastic anemia is a type of macrocytic anemia, in which large size red blood cells called as macrocytes are produced. These red blood cells are fewer in number. There is a decrease in white blood cell count and platelet count. Megaloblastic anemia occurs due to acquired deficiency of Vitamin B12. The reason can be an inadequate dietary intake of Vitamin B12 or any problem in the absorption of Vitamin B12 from the intestines.
In case of problem in the absorption of Vitamin B12 from intestines, it is known as Pernicious anemia. It occurs due to lack of intrinsic factor which is present in secretions of the stomach.
Vitamin B12 is also important for nerve health and is taken as a nutritional supplement for the treatment of nerve damage.
Vitamin B12 binds with intrinsic factor (protein secreted by cells in the stomach). After binding, a complex is formed which is absorbed by the small intestine. In case of any disease interfering in this process can cause weakening of absorption of Vitamin B12.
Know more about Vitamin B12
eGFR
Complete Blood Count
Blood Stag is composed of blood cells suspended in blood plasma (yellowish-colored liquid). The blood cells include red blood cells (also called RBCs or erythrocytes), white blood cells (also called WBCs or leukocytes), and platelets (also called thrombocytes).
Red blood cells (RBCs) are the most abundant blood cells. RBCs contain hemoglobin which helps in the transportation of oxygen to the tissues. RBC count is the measurement of the number of RBCs in a given volume of blood.
Packed Cell Volume (PCV) or Hematocrit (Hct) is the measurement of the blood volume occupied by RBCs. It is expressed in percentage.
White blood cells (WBCs) are key components of the immune system and thus protect the body from various infections and cancers. Total Leucocyte count (TLC) is the measurement of the total number of leukocytes (WBCs) in a given volume of blood.
There are five types of WBCs:
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Neutrophils
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Basophils
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Eosinophils
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Lymphocytes
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Monocytes
Differential Leucocyte Count (DLC) determines the percentage of different types of WBCs.
Neutrophils, Basophils, and Eosinophils are called Granulocytes because of the presence of granules inside these cells.
Absolute count of different types of WBCs is the measurement of their absolute numbers in the given volume of blood.
Platelet count - Platelets (also called thrombocytes) are disc-shaped cell fragments without a nucleus that help in blood clotting. Platelet count is the measurement of the number of platelets in a given volume of blood.
Mean Platelet Volume (MPV) is a measurement of the average size of platelets.
PDW or platelet distribution width refers to the variation of platelet size distribution
Hemoglobin (Hb) - Hemoglobin (Hb) is a protein found in red blood cells (RBCs) that carries oxygen from the lungs to the body tissues, exchanges the oxygen for carbon dioxide, and then carries the carbon dioxide back to the lungs where it is exchanged for oxygen.
Mean Corpuscular Volume (MCV) is the average volume of a red blood cell.
Mean Corpuscular Hemoglobin (MCH) is the average amount of hemoglobin in the average red blood cell.
Mean Corpuscular Hemoglobin Concentration (MCHC) is the average concentration of hemoglobin in a given volume of red cells.
Red Cell Distribution Width Coefficient of variation (RDW CV)is a measurement of the variability of the red blood distribution curve and their mean size.
Know more about Complete Blood Count
RDW CV
Absolute Neutrophil Count
An Absolute Neutrophil Count test measures the percentage of neutrophils per microliter of blood. Neutrophils are a type of WBC and play an integral part in the body's immune system. They help fight off bacterial infections in the body by identifying and destroying foreign invaders, such as disease-causing microorganisms.
Red Blood Cell Count
A Red Blood Cell Count test measures the total number of red blood cells in your blood. RBCs are the most abundant cells in the blood with an average lifespan of 120 days. These cells are produced in the bone marrow and destroyed in the spleen or liver. Their primary function is to help carry oxygen from the lungs to different body parts. The normal range of RBC count can vary depending on age, gender, and the equipment and methods used for testing.
Platelet Count
A Platelet Count test measures the average number of platelets in the blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days.
Platelets help stop the bleeding, whenever there is an injury or trauma to a tissue or blood vessel, by adhering and accumulating at the injury site and releasing chemical compounds that stimulate the gathering of more platelets. A loose platelet plug is formed at the site of injury and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps, including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this step, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding.
Absolute Basophil Count
An Absolute Basophil Count test measures the total number of basophils in the blood. Basophils are small, spherically-shaped cells that originate from bone marrow and make up almost 1% of the total white blood cells in the body. They attack a foreign substance and release proteins like histamine and heparin to destroy harmful substances, such as allergens, pathogens, or parasites. Histamine helps widen the blood vessels and make space for more immune cells to come to the site of infection or injury, whereas heparin acts as a blood-thinning agent and helps to avoid blood clotting at that site.
Absolute Monocyte Count
An Absolute Monocyte Count test measures the total number of monocytes in the blood. Monocytes are a type of WBC that originate from bone marrow and travel to different tissues via the blood. Once they are inside the tissue, these cells get converted to macrophages (a type of cell that digest harmful substances). Monocytes are the second line of defense mechanism of the human body after neutrophils. These cells are also responsible for the removal of injured or dead cells, microorganisms, and other insoluble particles from the blood.
Absolute Eosinophil Count
An Absolute Eosinophil Count test measures the number of eosinophils in the blood and provides important information about the functioning of the immune system. Eosinophils originate from bone marrow and have a lifespan of 8-18 hours. These cells are involved in fighting certain types of infections and responding to allergic reactions in the body. The eosinophils have varied functions including the physiological role in organ formation, such as the development of post-gestational mammary glands. Other functions of these cells include movement to the inflammation areas, trapping substances, killing cells, and bactericidal and antiparasitic activities. They also help in the treatment of immediate allergic reactions and modulation of inflammatory responses. By measuring the number of eosinophils in the blood, this test provides important information about the functioning of the immune system.
Hematocrit
A Hematocrit test measures the proportion of red blood cells (RBCs) in your blood as a percentage of the total blood volume. It is a crucial part of a complete blood count (CBC) and helps in assessing your blood health. RBCs are responsible for carrying oxygen from the lungs to different parts of the body. The hematocrit test provides valuable information about your blood's oxygen-carrying capacity.
Higher-than-normal amounts of RBCs produced by the bone marrow can cause the hematocrit to increase, leading to increased blood density and slow blood flow. On the other hand, lower-than-normal hematocrit can be caused by low production of RBCs, reduced lifespan of RBCs in circulation, or excessive bleeding, leading to a reduced amount of oxygen being transported by RBCs. Monitoring your hematocrit levels is essential for diagnosing and managing various blood-related disorders.
Mean Corpuscular Volume
A Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are uniform or vary significantly in size.
Mean Corpuscular Hemoglobin
An MCH test measures the average amount of hemoglobin in a single red blood cell (RBC). Hemoglobin is an iron-containing protein in RBCs, and its major function is to transport oxygen from the lungs to all body parts. This test provides information about how much oxygen is being delivered to the body by a certain number of RBCs.
Mean Corpuscular Hemoglobin Concentration
An MCHC test measures the average amount of hemoglobin in a given volume of RBCs. MCHC is calculated by dividing the amount of hemoglobin by hematocrit (volume of blood made up of RBCs) and then multiplying it by 100.
Mean Platelet Volume
An MPV test measures the average size of the platelets in your blood. Platelets are disk-shaped tiny cells originating from large cells known as megakaryocytes, which are found in the bone marrow. After the platelets are formed, they are released into the blood circulation. Their average life span is 7-10 days.
Platelets help stop bleeding whenever there is an injury or trauma to a tissue or blood vessel by adhering and accumulating at the injury site, and by releasing chemical compounds that stimulate the gathering of more platelets. After these steps, a loose platelet plug is formed at the site of injury, and this process is known as primary hemostasis. These activated platelets support the coagulation pathway that involves a series of steps including the sequential activation of clotting factors; this process is known as secondary hemostasis. After this, there is a formation of fibrin strands that form a mesh incorporated into and around the platelet plug. This mesh strengthens and stabilizes the blood clot so that it remains in place until the injury heals. After healing, other factors come into play and break the clot down so that it gets removed. In case the platelets are not sufficient in number or are not functioning properly, a stable clot might not form. These unstable clots can result in an increased risk of excessive bleeding.
Lipid Profile
A Lipid Profile test assesses the level of specific fat molecules called lipids in the blood and helps determine the risk of heart ailments. This test determines the amount of different types of lipids, including total cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides. Lipids play a pivotal role in the functioning of the body. They are crucial components of the cell membranes and hormones, provide cushioning, and are a storehouse of energy. Any alterations in the lipid levels may lead to potential heart ailments, making their monitoring crucial.
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Cholesterol - LDL
A Cholesterol - LDL test measures the concentration of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol plays an important role in your body. It carries cholesterol from your liver to other parts of the body where it's needed for things like building cell walls and making hormones. However, it is often referred to as "bad" cholesterol because when present in excess in your blood, it can stick to your blood vessel walls leading to the formation of plaque, making them narrow and less flexible. When this happens, it's harder for the blood to flow, which can lead to heart problems, like heart attacks and strokes. By measuring LDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and can recommend appropriate preventive or treatment strategies.
Triglycerides
A Triglycerides test measures the amount of triglycerides in the blood and helps evaluate your risk of developing cardiovascular diseases. Triglycerides are a type of fat (lipid) that your body uses as a source of energy. When you consume more calories than your body needs, the excess calories are converted into triglycerides and stored in fat cells for later use. High triglyceride levels can contribute to the hardening and narrowing of arteries, increasing the risk of heart attack, stroke, and other related conditions.
Cholesterol - Total
A Cholesterol - Total test measures the total amount of cholesterol (fats) in your blood. Cholesterol is mainly synthesized in the liver and partially in the intestines. It acts as a building block for cell membranes, serves as a precursor to vital hormones, and helps in the production of bile acids that help digest fats. Cholesterol is transported through the blood by two kinds of proteins: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). An optimal amount of these proteins is necessary for proper body functioning.
Cholesterol - HDL
A Cholesterol - HDL test measures the concentration of high-density lipoprotein (HDL) cholesterol in the blood. HDL cholesterol plays a crucial role in maintaining cardiovascular health, as it helps transport excess low-density lipoprotein (LDL) cholesterol from the bloodstream back to the liver for excretion. This process prevents the buildup of plaque on the blood vessel walls, which can cause them to become narrow and less flexible. Higher levels of HDL cholesterol are generally associated with a lower risk of heart problems, such as heart attacks and strokes. By measuring HDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and can recommend appropriate preventive or treatment strategies, including lifestyle modifications and medications.
Very Low Density Lipoprotein
A Very Low Density Lipoprotein test measures the concentration of very-low-density lipoprotein (VLDL) cholesterol in the blood. VLDL cholesterol plays a vital role in the body's metabolic processes. It is produced by the liver and is used to transport triglycerides, a type of fat, from the liver to various tissues throughout the body, where they are either utilized for energy or stored for later use. Though VLDL cholesterol is essential for the body's normal functioning, it is harmful if present in excess amounts. By measuring VLDL cholesterol levels, your doctor can assess your risk of developing cardiovascular diseases and recommend appropriate preventive or treatment strategies.
Total Cholesterol/HDL Cholesterol Ratio
LDL/HDL Ratio
An LDL/HDL Ratio test measures the ratio of low-density lipoproteins (LDL) to high-density lipoproteins (HDL) in your blood. These two types of lipoproteins carry cholesterol throughout the body. LDL, often referred to as the 'bad' cholesterol, carries cholesterol to the cells that need it. However, if there is too much LDL cholesterol in the blood, it can combine with other substances and form plaque in the arteries, leading to cardiovascular diseases. On the other hand, HDL, often referred to as the 'good' cholesterol, helps remove other forms of cholesterol, including LDL, from the bloodstream. It transports cholesterol back to the liver, where it is broken down and eliminated from the body, thus reducing the risk of cholesterol buildup and heart disease. The LDL/HDL ratio is a significant indicator of cardiovascular health. A high ratio indicates a higher amount of 'bad' cholesterol relative to 'good' cholesterol, implying a higher risk of developing heart disease. Conversely, a lower ratio implies a higher amount of 'good' cholesterol relative to 'bad' cholesterol, indicating a lower risk.
Non HDL Cholesterol
A Non HDL Cholesterol test looks for the “bad” cholesterol particles that are likely to contribute to heart problems. These bad particles include LDL (low-density lipoprotein) cholesterol, VLDL (very-low-density lipoprotein) cholesterol, and remnants of other cholesterol-carrying molecules. Cholesterol is a waxy substance that circulates in your bloodstream and is essential for various bodily functions. However, too much of “bad” types of cholesterol can build up in your arteries and increase the risk of heart conditions. LDL and VLDL cholesterol particles are often referred to as the "bad" cholesterol because they can stick to the walls of your arteries and form plaque, narrowing the arteries and restricting blood flow to your heart. By measuring non-HDL cholesterol, your doctor can assess your risk of heart disease and determine if any interventions or lifestyle changes are needed to protect your heart.
Total Iron Binding Capacity
Serum Transferrin
Iron Serum
Kidney Panel
Uric Acid
A Uric Acid test determines the level of uric acid in your body. Uric acid is a nitrogenous compound produced by the metabolic breakdown of purine. Purines are present as nitrogenous bases in the DNA and are also found in food like red meat and seafood.
Most uric acid dissolves in the blood and goes into your kidneys. From there, it passes through your body via the urine. Decreased elimination of uric acid is often a result of impaired kidney function due to kidney disease. In many cases, the exact cause of excess uric acid is unknown. Doctors seldom need to test for low levels of uric acid.
Blood Urea
A Blood Urea test measures the level of urea in the blood. Urea is a byproduct of protein metabolism. Proteins you consume in your diet are digested and converted into amino acids, which are then utilized by the body. This metabolic process produces a toxic byproduct known as ammonia. Ammonia is then rapidly converted into urea by your liver. Urea is comparatively less toxic than ammonia and is transported to the kidneys via the blood. The kidneys then filter it out through the urine. This process continues and the body keeps producing and eliminating urea, maintaining its low and steady levels in the blood.
BUN/Creatinine Ratio
Blood Urea Nitrogen
A Blood Urea Nitrogen test measures the levels of urea nitrogen in the blood. Blood urea is a waste product that is formed in the liver when you eat food and the protein is metabolized into amino acids. This process leads to the production of ammonia that is further converted into urea. Both ammonia and urea are nitrogenous compounds. Your liver releases urea into the blood which is then carried out to the kidneys. In the kidneys, urea is filtered from the blood and flushed out of the body via urine. This is a continuous process, so a small amount of urea nitrogen always remains in the blood.
In the case of a kidney or liver disease, there is a change in the amount of urea present in the blood. If your liver produces urea in an increased amount or if there is any problem in kidney functioning, there might be difficulty in filtering out the waste products from the blood, which can result in increased urea levels in the blood.