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Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Mean Corpuscular Volume

Also known as Mean cell volume
You need to provide
Blood
This test is for
Male, Female

Understanding Mean Corpuscular Volume


What is Mean Corpuscular Volume?

A Mean Corpuscular Volume test measures the average size of red blood cells (RBCs) in the blood. This test is a key indicator of anemia, several nutritional deficiencies, and other conditions related to RBC size variation. It is often done as part of a complete blood count test that also measures other types of blood cells.

Red blood cells help carry oxygen throughout the body, and their size can be an important indicator of how well they can transport oxygen. A Mean Corpuscular Volume blood test is helpful because having a large number of atypically large or small RBCs can indicate potential health concerns. A high MCV may indicate hypothyroidism, liver disease, aplastic anemia, hemolytic anemia, and reticulocytosis, whereas a low MCV may indicate iron-deficiency anemia or thalassemia.  

No special preparation is required before taking an MCV test; eat or drink as per your daily routine. Test result ranges are approximate and may differ slightly between different labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. The results will help them determine your medical condition and formulate your overall treatment plan.

What is Mean Corpuscular Volume used for?

A Mean Corpuscular Volume test can be done:

  • As part of a complete blood count test to monitor your overall health.

  • To evaluate symptoms suggestive of anemia, such as fatigue, pale skin, and lightheadedness. 

  • To identify different types of anemia and other genetic conditions like thalassemia.

  • To monitor and evaluate the effectiveness of the treatment for anemia and other conditions that can affect the size of red blood cells, such as liver disease or hypothyroidism.

  • As an additional test for many medical conditions.

What does Mean Corpuscular Volume measure?

A Mean Corpuscular Volume test measures the average size of your red blood cells, which carry oxygen through your body. This test tells whether your RBCs are uniform or vary significantly in size.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Mean Corpuscular Volume


Frequently Asked Questions about Mean Corpuscular Volume

Q. Which diseases can a Mean Corpuscular Volume test detect?

An MCV test can help identify different types of anemia and other health conditions related to the variation in RBC size.

Q. How is a Mean Corpuscular Volume test performed?

A Mean Corpuscular Volume test is done using a sample of blood drawn from a vein in your arm. The blood sample is collected in a vial and sent to the lab for analysis.

Q. Is there any risk associated with the MCV test?

There is no risk associated with this test. However, as the needle is used to prick and take out your blood, one may experience bleeding, swelling, or blood collection under the skin, which is usually self-limiting.

Q. What does it mean if your MCV is low?

A low MCV level means that the RBCs are smaller than normal in size and may indicate microcytic anemia. This condition may be caused by iron deficiency or thalassemia.

Q. What does it mean if your MCV is high?

High mean corpuscular volume (MCV), also known as macrocytosis, is associated with vitamin B12 deficiency anemia, folate deficiency anemia, hypothyroidism, liver disease, aplastic anemia, hemolytic anemia, and other rare inherited conditions such as orotic aciduria, Lesch-Nyhan syndrome, and reticulocytosis.
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