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Isosorbide Dinitrate + Hydralazine

Information about Isosorbide Dinitrate + Hydralazine

Isosorbide Dinitrate + Hydralazine Uses

Isosorbide Dinitrate+Hydralazine is used in the treatment of Heart failure.

How Isosorbide Dinitrate + Hydralazine works

Isosorbide dinitrate and Hydralazine. Isosorbide dinitrate is a nitrate which relaxes the blood vessels and decreases the oxygen demand of the heart. Hydralazine is a potassium channel opener which acts as an antioxidant and lessens tolerance to isosorbide dinitrate, thereby preserving its capacity to relax blood vessels. Together, they improve symptoms of heart failure.

Common side effects of Isosorbide Dinitrate + Hydralazine

Headache, Dizziness
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Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
13 Jun 2023 | 11:26 AM (UTC)

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Available Medicine for Isosorbide Dinitrate + Hydralazine

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Expert advice for Isosorbide Dinitrate + Hydralazine

  • Isosorbide Dinitrate + Hydralazine is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier.
  • This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away.
  • Isosorbide Dinitrate + Hydralazine may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It is best to avoid drinking alcohol while taking Isosorbide Dinitrate + Hydralazine as it may make the side effects worse.
  • Do not take it in combination with  medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure.
  • Do not stop taking Isosorbide Dinitrate + Hydralazine suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Frequently asked questions for Isosorbide Dinitrate + Hydralazine

Isosorbide Dinitrate + Hydralazine

Q. Can the use of Isosorbide Dinitrate+Hydralazine cause headache?

Isosorbide Dinitrate+Hydralazine can frequently cause headaches, especially at the start of the treatment. As the treatment continues, your headache may become less intense and frequent. However, inform your doctor if headache continues.

Q. Can the use of Isosorbide Dinitrate+Hydralazine cause dizziness?

Yes, the use of Isosorbide Isosorbide Dinitrate+Hydralazine can make you feel dizzy. This may often occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Q. Can I stop taking Isosorbide Dinitrate+Hydralazine if I feel well?

No, keep using Isosorbide Dinitrate+Hydralazine as advised by your doctor, even if you feel well. Stopping Isosorbide Dinitrate+Hydralazine suddenly may lead to serious complications of heart failure.

Q. Are there any special instructions regarding storage and disposal of this medicine?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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