Information about Hydralazine

Hydralazine Uses

Hydralazine is used in the treatment of Hypertension (high blood pressure). It is also used in combination with long-acting nitrates in heart failure.

How Hydralazine works

Hydralazine is a potassium channel opener. It works by relaxing blood vessels which lowers blood pressure and allows more blood and oxygen to reach the heart and other organs.

Common side effects of Hydralazine

Diarrhea, Headache, Increased heart rate, Loss of appetite, Nausea1a, Palpitations, Vomiting
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Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
14 Mar 2020 | 06:07 AM (UTC)

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Available Medicine for Hydralazine

DralgeenBharat Serums & Vaccines Ltd
4841 variant(s)
HydralazeDahlia Pharmaceutical Pvt Ltd
951 variant(s)
Hydralazine HydrochlorideBharat Serums & Vaccines Ltd
4001 variant(s)
AprezineRMPL Pharma LLP
5241 variant(s)

Expert advice for Hydralazine

  • It may cause dizziness. Do not drive or perform activities that require mental focus until you know how Hydralazine affects you. 
  • Avoid taking alcohol while taking this medication as it may lead to increased side effects.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Inform your doctor about taking this medicine before undergoing any surgical procedure. 
  • Your doctor may get your blood and urine test done regularly if you have been taking this medicine for a long time.
  • Do not stop taking this medicine suddenly without talking to your doctor. 

Frequently asked questions for Hydralazine

Hydralazine

Q. What is Hydralazine? What is it used for?

Hydralazine belongs to a class of medicines known as potassium channel openers. It helps in the removal of potassium from the walls of arteries. This results in increased space in the arteries for the blood to flow easily, thereby reducing the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for the treatment of angina.

Q. Can I stop taking Hydralazine?

No, you should not stop taking Hydralazine without consulting your doctor. Suddenly stopping the medication may cause reoccurring of your anginal pain. It would be better to consult your doctor if you are experiencing any side effects.

Q. How long does it take Hydralazine to start working?

Hydralazine starts working after about an hour of taking the medicine. However, full benefits may be seen only after 4 to 5 days. Consult your doctor if you do not notice any significant improvement in your condition.

Q. For how long do I need to continue Hydralazine?

Hydralazine is generally prescribed for a long term. You may even need to take it for the rest of your life. You should continue taking your medicine for as long as your doctor tells you. However, if you experience any bothersome side effects, consult your doctor.

Q. What if somebody accidentally takes an excess of Hydralazine?

Taking Hydralazine in excess may cause low blood pressure and the person may feel weak or dizzy. Also, one may experience irregular or fast heartbeat. In case of an overdose, immediately consult the doctor and seek emergency medical help.

Q. Can I take Hydralazine if I am taking aspirin?

You should avoid taking Hydralazine and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor if you notice blood in your stool or vomit while using Hydralazine.

Q. Who should not use Hydralazine?

People who are allergic to Hydralazine or any of its ingredients should avoid using Hydralazine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Hydralazine. Additionally, it is advised to avoid using Hydralazine in people taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat). This is because these medicines may interfere with the working of Hydralazine and affect your blood pressure. Fluctuations in blood pressure could also be due to low blood volume.

Q. Can Hydralazine affect my sex life?

No, Hydralazine does not affect your sex life. However, it is not recommended to take Hydralazine with other medications used for the treatment of erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine). Taking these together can lead to a serious drop in your blood pressure. Consult your doctor if you are not sure.

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