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Glibenclamide + Metformin + Rosiglitazone

Information about Glibenclamide + Metformin + Rosiglitazone

Glibenclamide + Metformin + Rosiglitazone Uses

Glibenclamide+Metformin+Rosiglitazone is used in the treatment of type 2 diabetes mellitus.

How Glibenclamide + Metformin + Rosiglitazone works

Glibenclamide + Metformin + Rosiglitazone is a combination of three antidiabetic medicines: Glibenclamide , Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity. Glibenclamide, Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity.

Common side effects of Glibenclamide + Metformin + Rosiglitazone

Hypoglycemia (low blood glucose level), Nausea1a, Taste change, Diarrhea, Stomach pain, Headache, Edema (swelling), Weight gain, Blurred vision, Bone fracture, Respiratory tract infection
CONTENT DETAILS
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
18 Feb 2020 | 11:54 AM (UTC)

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Expert advice for Glibenclamide + Metformin + Rosiglitazone

  • Take it with food to lower your chance of having an upset stomach.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

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