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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Zoladex 3.6 Injection


Product introduction

Zoladex 3.6 Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis and uterine fibroids in women. In combination with some other medicine, it is used in the treatment of female infertility.

Zoladex 3.6 Injection is used to treat prostate cancer in men and to aid women in getting pregnant and treat endometriosis in women (condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere)

Benefits of Zoladex Injection

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Zoladex 3.6 Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Breast cancer

Zoladex 3.6 Injection relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

In Endometriosis

Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Zoladex 3.6 Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.

In Uterine fibroids

Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Zoladex 3.6 Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further. Take this medicine as advised by the doctor to get the most benefit.

In Female infertility

Zoladex 3.6 Injection is used in combination with other medicines to treat infertility in women. It helps to control the release of eggs from the ovaries. You should use the medicine as prescribed for it to be effective.

Side effects of Zoladex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoladex

  • Decreased libido
  • Erectile dysfunction
  • Depression
  • Headache
  • Dizziness
  • Nausea
  • High blood pressure
  • Breast atrophy
  • Pain during sexual intercourse
  • Hot flushes
  • Sexual dysfunction
  • Urinary tract disorder
  • Lethargy
  • Pain
  • Edema (swelling)
  • Upper respiratory tract infection
  • Rash
  • Sweating
  • Decreased appetite
  • Chronic obstructive pulmonary disease (COPD)
  • Heart failure
  • Insomnia (difficulty in sleeping)
  • Vaginal inflammation
  • Emotional lability
  • Acne
  • Breast enlargement
  • Pelvic discomfort
  • Application site reactions (burning, irritation, itching and redness)
  • Pain during periods
  • Uterine bleeding

How to use Zoladex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zoladex Injection works

Zoladex 3.6 Injection is a synthetic hormone. In men, it works by reducing the level of testosterone (male hormone) which causes regression of prostate tumor and improves symptoms. In women, it suppresses the level of estradiol (female hormone) which helps treat advanced breast cancer, endometriosis and uterine fibroids. It also reduces the thickness of the endometrium, which is the uterus lining, prior to surgery.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zoladex 3.6 Injection. Please consult your doctor.
Pregnancy
UNSAFE
Zoladex 3.6 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Zoladex 3.6 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Zoladex 3.6 Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Zoladex 3.6 Injection is safe to use in patients with kidney disease. No dose adjustment of Zoladex 3.6 Injection is recommended.
Liver
SAFE IF PRESCRIBED
Zoladex 3.6 Injection is safe to use in patients with liver disease. No dose adjustment of Zoladex 3.6 Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zoladex 3.6 Injection
₹9754.0/Injection
Goselin 3.6mg Injection
Bharat Serums & Vaccines Ltd
₹8571.42/injection
12% cheaper

Quick tips

  • Zoladex 3.6 Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis, and uterine fibroids in women.
  • It may also be used along with other medicines to treat infertility in women.
  • It is a prefilled syringe that is injected under the skin of the abdomen, every 28 days.
  • It may cause a reduction in bone mineral density and weakened bones. Your doctor may prescribe other medicines to reduce bone loss.
  • Inform your doctor if you start to feel depressed or have disturbing thoughts or feelings during treatment with this medicine.
  • Vaginal bleeding may occur in the first month after starting treatment and usually stops on its own. Inform your doctor if bleeding continues.

Fact Box

Chemical Class
GNRH Analogue
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
GNRH agonists/analogue

Patient concerns

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My Dr. has given dose of inj. Zoladex 3.6 mg for endometriosis, 3 doses of its are compulsory or 2 doses are sufficient, because I have some side effects like sleeping problem, headache and sickness. Please suggest me.
Dr. Megha Gupta
Obstetrics and Gynaecology
Zoladex is a hormonal treatment. Please cpntinue as prescribed.
Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Not a symptom of prostate cancer
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Goserelin acetate. Luton, Bedfordshire: AstraZeneca UK Limited; 2001 [revised 24 Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  2. Goserelin acetate implant. Macclesfield, England: AstraZeneca UK Limited; 2009. [Accessed 02 Apr. 2019] (online) Available from:External Link
  3. UpToDate. Goserelin: Drug information. [Accessed 25 Jun. 2019] (online) Available from:External Link
  4. OncoLink. Goserelin Acetate. [Accessed 25 Jun. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: United kingdom

MRP
9754
Inclusive of all taxes
1.0 Injection in 1 vial
SOLD OUT
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