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Zefretol 400 Tablet


Product introduction

Zefretol 400 Tablet is a prescription medicine used to treat epilepsy (seizures). It helps to decrease the abnormal and excessive activity of the nerve cells and calms the brain.

Zefretol 400 Tablet is used to treat epileptic seizures and also for some mental behavioural disorders

Uses of Zefretol Tablet

Benefits of Zefretol Tablet

In Epilepsy/Seizures

Zefretol 400 Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Zefretol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zefretol

  • Sleepiness
  • Blurred vision
  • Nausea
  • Headache
  • Vomiting
  • Double vision
  • Fatigue
  • Balance disorder (loss of balance)
  • Diarrhea
  • Impaired coordination
  • Vertigo
  • Decreased appetite
  • Decreased sodium level in blood
  • Dizziness

How to use Zefretol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zefretol 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zefretol Tablet works

Zefretol 400 Tablet is an anti epileptic medication. It works by blocking the voltage gated sodium channels that stabilizes the hyperexcited nerve cells in the brain. In this way, it treats seizures or fits.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zefretol 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Zefretol 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Zefretol 400 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Zefretol 400 Tablet should be used for short periods and sleepiness of the baby should be watched.
Driving
UNSAFE
Zefretol 400 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Zefretol 400 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zefretol 400 Tablet may be needed. Please consult your doctor.
Use of Zefretol 400 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Zefretol 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zefretol 400 Tablet may be needed. Please consult your doctor.
Use of Zefretol 400 Tablet is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zefretol 400 Tablet
₹10.7/Tablet
Eslizen 400mg Tablet
Intas Pharmaceuticals Ltd
₹21.5/tablet
101% costlier
₹14/tablet
31% costlier
Eslicar 400mg Tablet
Emcure Pharmaceuticals Ltd
₹37/tablet
246% costlier
Eslify 400mg Tablet
Torrent Pharmaceuticals Ltd
₹15.5/tablet
45% costlier
₹14/tablet
31% costlier

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • It may cause a reduction in blood sodium level (hyponatremia). Your doctor may monitor your blood sodium level regularly.
  • Inform your doctor if you notice skin reaction such as rash, skin peeling, and itching while using this medicine.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Carboxamide Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium channel modulators (AED)

Patient concerns

arrow
She has problem of epilepsy from last two years
Dr. Rahul Yadav
Paediatrics
Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.
I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal
Dr. M. K. Ansari
Neurology
not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare
arrow

User feedback


FAQs

Can I stop taking if I start feeling better?

No, stopping Zefretol 400 Tablet suddenly can increase your risk of having more seizures. Your doctor will advise you on how long you should take this medicine. If your doctor decides to stop Zefretol 400 Tablet, your dose will usually be reduced gradually. It is important that you complete your treatment as advised by your doctor or your symptoms may get worse.

Can Zefretol 400 Tablet cause suicidal thoughts?

Like all other anti-epileptic medicines, Zefretol 400 Tablet may also cause suicidal thoughts. However, this occurs only in a small number of people.

Can Zefretol 400 Tablet be taken if I have kidney-related problems?

Inform your doctor if you are suffering from any kidney-related problems. Your doctor will monitor your kidney function (creatinine clearance) regularly and may adjust your dose of Zefretol 400 Tablet accordingly.

Does Zefretol 400 Tablet affect the liver?

Inform your doctor if you are suffering from liver disease as few people have shown a negative effect on the liver with the use of Zefretol 400 Tablet. Your doctor may monitor your liver functions regularly.

How can I look for early symptoms of suicidal thoughts and actions?

Pay attention to any changes, especially sudden changes in mood, behaviour, thoughts or feelings. Keep all follow-up visits with your doctor as scheduled. Call your doctor as needed, especially if you are worried about any symptoms.

If I were to have an allergic reaction with Zefretol 400 Tablet, what would my symptoms look like?

Zefretol 400 Tablet may cause allergic reactions or serious problems that may impact organs and other parts of your body like the liver or blood cells. Consult your doctor straight away if you develop rashes, hives, itchiness, swelling, trouble swallowing or difficulty in breathing.

Can I participate in sports when taking Zefretol 400 Tablet?

Your doctor will guide you about activities that are okay for you.

How will I know that my sodium levels are low while taking Zefretol 400 Tablet?

If your blood sodium levels become low during the course of Zefretol 400 Tablet, you may experience worsening of seizures, confusion and decreased consciousness. Immediately consult your doctor if you develop any of these symptoms.

Can Zefretol 400 Tablet be taken with Carbamazepine?

The dose of Zefretol 400 Tablet may need to be adjusted if you take Carbamazepine with Zefretol 400 Tablet. The reason being, Carbamazepine interferes with its working.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Eslicarbazepine acetate. Hatfield, Hertfordshire: Eisai Ltd.; 2009 [revised May 2018]. [Accessed 28 Jan. 2019] (online) Available from:External Link
  2. Drugs.com. Eslicarbazepine. [Accessed 01 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Eslicarbazepine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India

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