Xortib 150mg Tablet is used in the treatment of cancer of breast, colon, and rectum. It may be also used to treat other conditions, as determined by the doctor. It is used alone or in combination with some other medicine as a part of chemotherapy.

Xortib 150mg Tablet is used to treat severe forms of a skin disease (psoriasis) and to treat several disorders of joint disorders leading to painful swelling and redness of the joints.

Uses of Xortib Tablet

Benefits of Xortib Tablet

In Breast cancer

Xortib 150mg Tablet helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Xortib 150mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Xortib 150mg Tablet treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

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Side effects of Xortib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xortib

Vomiting
Weakness
Nausea
Abdominal pain
Diarrhea
Blisters on fingers/feet

How to use Xortib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xortib 150mg Tablet is to be taken with food.

How Xortib Tablet works

Xortib 150mg Tablet is an anticancer medication. Inside the body, this medicine gets converted into 5-fluorouracil (chemical). This chemical hampers the synthesis of genetic materials (RNA and DNA) in the cancer cells, thereby interferes with their growth. This slows down the growth of cancer cells and eventually kills them.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xortib 150mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Xortib 150mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Xortib 150mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Xortib 150mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Xortib 150mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xortib 150mg Tablet may be needed. Please consult your doctor.
Use of Xortib 150mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Xortib 150mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Xortib 150mg Tablet may be needed. Please consult your doctor.
Use of Xortib 150mg Tablet is not recommended in patients with severe kidney disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Xortib 150mg Tablet

₹78.0/Tablet

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Medicamen Biotech Ltd

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Quick tips

Xortib 150mg Tablet is used alone or in combination with other medicines for the treatment of colon, rectum or breast cancers.
It is oral chemotherapy, hence it is preferred by many patients.
It should be taken within 30 minutes after eating a meal.
The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
It may cause dizziness and tiredness. Don't drive or do anything requiring concentration until you know how it affects you.
Frequency of hair loss is much less compared to other chemotherapy drugs.
Do not take it if you are pregnant or breastfeeding.
Your doctor may regularly monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice signs of infection such as fever, sore throat, rash or severe diarrhea.
Inform your doctor immediately if you start to have side effects such as diarrhea, vomiting, nausea, mouth sores, chest pain or loss of appetite.

Fact Box

Chemical Class

Deoxycytidine Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Patient concerns

If any symtom of brest cancer if have whats the cure

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

First is confirmation of breast cancerChance of cure depends on stage of cancer

I am PATIENT have pain in my breastes and feel very weight before one week of my menstrual perieds date Is it any symptoms of breast cancer ? Need your advice And also having back pain during menstrual dates please give your valubel advice

Dr. Suman Rao

Obstetrics and Gynaecology

No it's not a symptom of breast cancer.

FAQs

What are the side effects of Xortib 150mg Tablet?

The side effects of Xortib 150mg Tablet include stomach pain or upset stomach, constipation, loss of appetite, and change in ability to taste food. It may also cause increased thirst, unusual tiredness or weakness, dizziness, headache, hair loss, skin rash, back, join, or muscle pain. You may also experience red, swollen, itchy, or teary eyes and trouble falling asleep or staying asleep. Inform your doctor if any of these symptoms are severe and persist for long.

What are the serious side effects of Xortib 150mg Tablet?

The use of Xortib 150mg Tablet may cause various serious side effects such as diarrhea, nausea, vomiting, sores in the mouth, swelling, pain, redness, or peeling of skin on the palms and soles of the feet. One may also experience fever, chills, sore throat, or other signs of an infection, swelling of the hands, feet, ankles, or lower legs, chest pain or pressure, fast heartbeat, dark urine and yellowing of the skin or eyes. Inform your doctor immediately if you experience any such symptoms.

Does Xortib 150mg Tablet make you tired?

Yes, Xortib 150mg Tablet may make you tired and you may also feel weak, as these are the most common side effects of the medicine. Hence, it is possible that use of Xortib 150mg Tablet may affect your ability to drive or operate machinery.

What is the most important information that I should know about Xortib 150mg Tablet?

It is important to know that Xortib 150mg Tablet can interfere with working of blood thinners like warfarin. This type of interference can cause a change in the rate of clot formation and can cause bleeding that can even lead to death. The risk is higher for cancer patients, especially those who are over 60 years of age. Seek immediate medical help if you experience symptoms like unusual bleeding, vomiting or spitting up blood or brown material that resembles coffee grounds, bloody or black, tarry stools, blood in urine, red or dark-brown urine, or easy bruising.

How long do I need to take Xortib 150mg Tablet?

The duration of treatment with Xortib 150mg Tablet depends on the nature of your illness and individual response to treatment. Usually, it is given as a series of treatment cycles, each of these cycles lasts for 21 days. Xortib 150mg Tablet is given for 14 days followed by a rest period of 7 days. You should continue taking this medicine for the time prescribed by the doctor.

Do I need to use birth control method while using Xortib 150mg Tablet?

Yes, birth control methods are a must while using Xortib 150mg Tablet, as this medicine may harm your unborn child. Females should continue using these methods for 6 months after the final dose. On the other hand, men using these medicines whose partners can become pregnant should use effective birth control during treatment and for 3 months after the final dose.

What kind of drug is Xortib 150mg Tablet?

Xortib 150mg Tablet is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Xortib 150mg Tablet is classified as an "antimetabolite." Xortib 150mg Tablet itself is not a cytostatic medicine; it gets converted into an active anti-cancer medicine (more in tumour tissue than in normal tissue) only after getting absorbed by the body.

Do I need to get any tests done while on Xortib 150mg Tablet?

The doctor will check you on a regular basis while you are taking Xortib 150mg Tablet to monitor side effects and your response to therapy. You may need to get your blood test done as advised by the doctor to monitor your complete blood count (CBC) as well as the function of kidneys and liver.

Should Xortib 150mg Tablet be taken with or without food?

Capecitabine should be taken within 30 minutes after finishing a meal. Swallow tablets as a whole (do not cut or crush) with water. Consult your doctor if you cannot take the whole tablet. If Xortib 150mg Tablet needs to be crushed or cut, it should be done by a trained professional using appropriate equipment and safety procedures.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1698.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 947.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 191.
Drugs.com. Capecitabine. [Accessed 26 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Capecitabine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Fresenius Kabi. Capecitabine [producr Information]. [Accessed 12 Jun, 2023] (online) Available from:

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