Velcade 1mg Injection
Prescription Required
Product introduction
Velcade 1mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
Velcade 1mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking Velcade 1mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Velcade 1mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking Velcade 1mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Uses of Velcade Injection
Benefits of Velcade Injection
In Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Velcade 1mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
In Mantle-cell lymphoma
Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Velcade 1mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
Side effects of Velcade Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Velcade
- Low blood platelets
- Fatigue
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Psychiatric disturbances
- Nausea
- Vomiting
- Loss of appetite
- Fever
- Anemia (low number of red blood cells)
- Diarrhea
- Decreased appetite
- Decreased white blood cell count (neutrophils)
- Constipation
How to use Velcade Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
UNSAFE
Velcade 1mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Velcade 1mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Velcade 1mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Velcade 1mg Injection may cause side effects which could affect your ability to drive.
Velcade 1mg Injection might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.
Velcade 1mg Injection might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.
Kidney
CAUTION
Velcade 1mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Velcade 1mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Velcade 1mg Injection in these patients.
Limited information is available on the use of Velcade 1mg Injection in these patients.
Liver
CAUTION
Velcade 1mg Injection should be used with caution in patients with liver disease. Dose adjustment of Velcade 1mg Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Velcade 1mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
- Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet.
Fact Box
Chemical Class
Phenylalanine Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Proteasome inhibitor
Patient concerns
FAQs
Q. When should I call my doctor right away?
Get medical help right away if you have muscle cramping, muscle weakness, confusion, visual loss or disturbances, blindness, seizures, headaches, shortness of breath, swelling of your feet or changes in your heartbeat, high blood pressure, tiredness, fainting, coughing and breathing difficulties or tightness in the chest.
Q. How will you know that Velcade 1mg Injection is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
Q. What precautions should I take to reduce the chances of getting infected during treatment with Velcade 1mg Injection?
Since Velcade 1mg Injection lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.
Q. Can Velcade 1mg Injection be used during pregnancy?
No, this medicine should not be used during pregnancy as it can harm your unborn baby. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 3 months after the last dose of Velcade 1mg Injection.
Q. Can Velcade 1mg Injection affect my lungs? What should I do?
Yes, this medicine might cause potentially fatal problems in your lung. If you feel severe shortness of breath, confusion, dry cough, dizziness, or extreme tiredness, talk to your doctor right away.
Q. Does Velcade 1mg Injection cause hair loss?
Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.
Q. Are there any precautions for tingling sensation and numbness in my arms and legs?
This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.
Q. I have noticed some changes in my skin after taking Velcade 1mg Injection? What should I do?
Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen with (SPF more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water bath and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.
Q. How to relieve constipation during the treatment?
To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
Q. I am experiencing nausea and extreme tiredness. Is this due to Velcade 1mg Injection?
Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.
Q. I am noticing a change in my taste. How shall I improve my taste?
You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1742-43.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 958.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 153-54.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- Bortezomib. Beerse Belgium: Janssen Pharmaceutica NV; [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Country of origin: Belgium
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₹18060
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1.0 Injection in 1 vial
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