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Last updated
05 Dec 2023 | 06:15 PM (IST)

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Udnus SR 450 Tablet

Prescription Required
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Product introduction

Udnus SR 450 Tablet is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones.

Udnus SR 450 Tablet is used to restore the function of the liver.

Uses of Udnus Tablet SR

Benefits of Udnus Tablet SR

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Udnus SR 450 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

In Treatment of Gallbladder stones

Udnus SR 450 Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

Side effects of Udnus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Udnus

  • Abdominal pain
  • Diarrhea
  • Hair loss
  • Itching
  • Nausea
  • Rash

How to use Udnus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Udnus SR 450 Tablet is to be taken with food.

How Udnus Tablet SR works

Udnus SR 450 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety advice

Alcohol
UNSAFE
Udnus SR 450 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Udnus SR 450 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Udnus SR 450 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Udnus SR 450 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Udnus SR 450 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Udnus SR 450 Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Udnus SR 450 Tablet
₹50.3/Tablet SR
Ursocol SR 450 Tablet
Sun Pharmaceutical Industries Ltd
₹16.5/tablet sr
65% cheaper
Udimarin Forte SR Tablet
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₹55.1/tablet sr
16% costlier
Ursetor SR 450 Tablet
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₹39.67/tablet sr
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Uda 450 SR Tablet
Tas Med India Pvt Ltd
₹41.75/tablet sr
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₹31.6/tablet sr
33% cheaper

Quick tips

  • Udnus SR 450 Tablet should be taken after a meal with a glass of milk or water.
  • Eat a healthy diet, exercise regularly, and avoid alcohol intake.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
  • Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class
Bile Acids and Salts
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives

Patient concerns

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Gallbladder Stones giving. Patient is having asthama
Dr. Praveen Pushkar
Urology
Consult g i surgeon
medicine for gallbladder stone in homeopathy I have multiple stones in gall blader. largest 10mm
Dr. Praveen Pushkar
Urology
Sir m a urologist. Consult homeopathy
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FAQs

When should I take Udnus SR 450 Tablet?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Udnus SR 450 Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Is Udnus SR 450 Tablet safe?

Udnus SR 450 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

How does Udnus SR 450 Tablet help the liver?

Udnus SR 450 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Does Udnus SR 450 Tablet cause weight gain?

Yes, there is a chance of weight gain with Udnus SR 450 Tablet, but it is not common. The use of Udnus SR 450 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

What should I avoid while taking Udnus SR 450 Tablet?

While taking Udnus SR 450 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Udnus SR 450 Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Udnus SR 450 Tablet. So, ask your doctor about the time gap that should be maintained between Udnus SR 450 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Udnus SR 450 Tablet.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  2. Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  4. Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from:External Link
  5. The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Winsun Life Sciences Pvt Ltd
Address: H NO- 735-E THIRD FLOOR,MAIN 100 FEET ROAD EAST BABARPUR DELHI-32
Country of origin: India

MRP
503
Inclusive of all taxes
10.0 tablet sr in 1 strip
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