Toplift XL 37.5mg Capsule SR
Prescription Required
Product introduction
Toplift XL 37.5mg Capsule SR is used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate, and unwanted or racing thoughts.
Toplift XL 37.5mg Capsule SR is used to treat depression and anxiety disorder.
Toplift XL 37.5mg Capsule SR is used to treat depression and anxiety disorder.
Uses of Toplift XL Capsule SR
Benefits of Toplift XL Capsule SR
In Depression
Toplift XL 37.5mg Capsule SR helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Toplift XL 37.5mg Capsule SR prevents extreme mood changes and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
In Anxiety disorder
Toplift XL 37.5mg Capsule SR works by stopping your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with Anxiety disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Toplift XL Capsule SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Toplift XL
- Nausea
- Vomiting
- Dizziness
- Insomnia (difficulty in sleeping)
- Decreased appetite
- Anxiety
- Constipation
- Increased sweating
- Sexual dysfunction
How to use Toplift XL Capsule SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Toplift XL 37.5mg Capsule SR is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Toplift XL 37.5mg Capsule SR.
Pregnancy
CONSULT YOUR DOCTOR
Toplift XL 37.5mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Toplift XL 37.5mg Capsule SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Driving
UNSAFE
Toplift XL 37.5mg Capsule SR may cause side effects which could affect your ability to drive.
As side effects of Toplift XL 37.5mg Capsule SR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
As side effects of Toplift XL 37.5mg Capsule SR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Kidney
CAUTION
Toplift XL 37.5mg Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Toplift XL 37.5mg Capsule SR may be needed. Please consult your doctor.
Liver
CAUTION
Toplift XL 37.5mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Toplift XL 37.5mg Capsule SR may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Toplift XL 37.5mg Capsule SR helps in treating depression and anxiety.
- It may take 2 to 4 weeks for Toplift XL 37.5mg Capsule SR to start working. Keep taking it as prescribed.
- It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Toplift XL 37.5mg Capsule SR as it may cause excessive drowsiness and increase the risk of liver damage.
- It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Anisole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Patient concerns
FAQs
Q. Can Toplift XL 37.5mg Capsule SR cause sedation?
Yes. Toplift XL 37.5mg Capsule SR can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Toplift XL 37.5mg Capsule SR.
Q. Is Toplift XL 37.5mg Capsule SR a psychotropic drug?
Yes. Toplift XL 37.5mg Capsule SR is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.
Q. Is Toplift XL 37.5mg Capsule SR a narcotic?
No. Toplift XL 37.5mg Capsule SR is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
Q. What is the difference between Toplift XL 37.5mg Capsule SR ER and XR?
Both are same medication. Toplift XL 37.5mg Capsule SR ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.
Q. Can I take mirtazapine along with Toplift XL 37.5mg Capsule SR?
No. There can be a serious side effect when mirtazapine is taken with Toplift XL 37.5mg Capsule SR. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.
Q. Can I take Toplift XL 37.5mg Capsule SR with citalopram?
No. Citalopram and Toplift XL 37.5mg Capsule SR both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.
Q. What is the relation between Toplift XL 37.5mg Capsule SR and p-glycoprotein?
P-glycoprotein is responsible for the expulsion of Toplift XL 37.5mg Capsule SR from the brain. Some studies have shown that Toplift XL 37.5mg Capsule SR and its metabolite inhibit the p-glycoprotein.
Q. Where is Toplift XL 37.5mg Capsule SR absorbed?
Toplift XL 37.5mg Capsule SR is absorbed from the intestine after being metabolised by the liver.
Q. When should I take Toplift XL 37.5mg Capsule SR?
Toplift XL 37.5mg Capsule SR is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.
Q. Can Toplift XL 37.5mg Capsule SR cause high blood pressure?
Toplift XL 37.5mg Capsule SR treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Toplift XL 37.5mg Capsule SR should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.
Q. Can Toplift XL 37.5mg Capsule SR cause constipation?
Yes. Toplift XL 37.5mg Capsule SR is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.
Q. Can Toplift XL 37.5mg Capsule SR cause weight loss?
Yes. Toplift XL 37.5mg Capsule SR is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Toplift XL 37.5mg Capsule SR for several weeks. Please consult your doctor if it bothers you.
Q. Can Toplift XL 37.5mg Capsule SR cause addiction?
No. Toplift XL 37.5mg Capsule SR does not have habit-forming potential.
Q. Can I take Toplift XL 37.5mg Capsule SR tablet instead of a capsule?
You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.
Q. Can gabapentin be given along with Toplift XL 37.5mg Capsule SR?
Yes. Gabapentin can be given with Toplift XL 37.5mg Capsule SR but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.
Q. What is the difference between Toplift XL 37.5mg Capsule SR and desvenlafaxine?
Desvenlafaxine is an active metabolite of Toplift XL 37.5mg Capsule SR. It is the same medication in an active form.
Q. Can fibromyalgia be treated with Toplift XL 37.5mg Capsule SR?
Toplift XL 37.5mg Capsule SR is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Toplift XL 37.5mg Capsule SR in the treatment of fibromyalgia. Consult your doctor before starting this medication.
Q. Can nerve pain be treated with Toplift XL 37.5mg Capsule SR?
Toplift XL 37.5mg Capsule SR is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.
Q. Why does Toplift XL 37.5mg Capsule SR cause loss of appetite?
Toplift XL 37.5mg Capsule SR is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.
Q. What are good alternatives to Toplift XL 37.5mg Capsule SR, particularly when a side effect is reduced sex drive?
If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Toplift XL 37.5mg Capsule SR by yourself it can lead to increased adverse effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
- DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
- Venlafaxine [FDA Label]. Marietta, GA: Urban Pharmaceuticals Inc.; 1993 [revised Jun. 2014]. [Accessed 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Venlafaxine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Marketer details
Name: Ishjas Pharma Pvt Ltd
Address: X-936 GALI NO. 3, CHAND MOHALLA OPP. GBS SCHOOL GHANDHI NAGAR DELHI DL 110031 INDIA
Country of origin: India
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