Author Details
Written By
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Topgain Liquid

Prescription Required

Product introduction

Topgain Liquid is a vasodilator used in the treatment of certain hypertension cases. It is generally used as a second-line treatment when other antihypertensive medicines have not been effective or are not suitable for a patient. It relaxes and widens the blood vessels, allowing blood to flow more easily.

Topgain Liquid is known as a vasodilator. It is used to treat hypertension and also to manage heart failure

Benefits of Topgain Liquid

In Treatment of Hypertension (high blood pressure)

Topgain Liquid helps lower blood pressure by relaxing and widening the blood vessels, reducing peripheral vascular resistance. It is particularly useful in certain cases of resistant hypertension when other antihypertensive medications do not work or are contraindicated.

Side effects of Topgain Liquid

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Topgain

  • Hypotension (low blood pressure)
  • Headache
  • Hypertrichosis (excessive hair growth)
  • Weight gain
  • Tachycardia
  • Decreased white blood cell count
  • ECG changes

How to use Topgain Liquid

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Topgain Liquid may be taken with or without food, but it is better to take it at a fixed time.

How Topgain Liquid works

Topgain Liquid belongs to the class of medicine known as potassium channel openers. It is an antihypertensive peripheral vasodilator. It works by opening adenosine triphosphate-sensitive potassium channels in vascular smooth muscle cells. This helps to dilate the arteries (blood vessels) to increase the blood flow and to decrease the blood pressure.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Topgain Liquid.
Pregnancy
CONSULT YOUR DOCTOR
Topgain Liquid may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Topgain Liquid is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Topgain Liquid may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Topgain Liquid should be used with caution in patients with kidney disease. Dose adjustment of Topgain Liquid may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Topgain Liquid in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • It may cause dizziness. Do not drive or perform activity require mental focus until you know how Topgain Liquid affects you.
  • Do not consume alcohol while taking Topgain Liquid as it may cause increased dizziness.
  • It can cause salt and water build up in your body. Monitor your weight regularly and inform your doctor if you gain weight, as this could indicate that your body is retaining too much fluid.
  • It may cause increased body hair growth. This is reversible within one to six months of stopping treatment.
  • Do not stop taking Topgain Liquid suddenly without talking to your doctor.

Fact Box

Chemical Class
Dialkylarylamines
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Potassium channel opener

Patient concerns

arrow
I am a patient of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinal condition of high blood pressure. Please see a physician.
Some times I had lot of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
arrow

FAQs

What is Topgain Liquid and what is it used for?

Topgain Liquid belongs to a class of medicines known as potassium channel openers. It helps in relaxing blood vessels. Widening peripheral blood vessels will decrease blood pressure. This decreases the workload of the heart to pump the blood and helps in the treatment of certain hypertension cases.

Can I stop taking Topgain Liquid?

No, you should not stop taking Topgain Liquid without speaking to your doctor first. If you stop Topgain Liquid suddenly, rebound hypertension may occur. Talk to your doctor if you are experiencing any side effects.

How long does it take Topgain Liquid to start working?

Topgain Liquid starts working after about an hour of taking the medicine, but full benefits may be seen only after 7 days.

For how long do I need to continue Topgain Liquid?

Continue taking your medicine for as long as your doctor tells you. Topgain Liquid is generally prescribed for a long term. You may even need to take it for the rest of your life.

What if somebody accidentally takes excess of Topgain Liquid?

He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.

Who should not use Topgain Liquid?

People who are allergic to Topgain Liquid or any of its ingredients should avoid using this medicine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Topgain Liquid. Additionally, patients taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil, and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat) should not use the medication. Your blood pressure may be affected if these medicines are taken with Topgain Liquid or if you have low blood volume.

Can Topgain Liquid affect my sex life?

No, Topgain Liquid does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Topgain Liquid. Taking them together can lead to a serious drop in your blood pressure.
Related lab tests

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1829.
  2. Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 179.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 922-24.
  4. Minoxidil. Sandwich, Kent: Pfizer Limited; 1995 [revised Jun. 2018]. [Accessed 30 Jan. 2019] (online) Available from:External Link
  5. Minoxidil tablets. New York, New York: Pharmacia & Upjohn Company; 2015. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 18 Mar. 2019] (online) Available from:External Link
  7. Minoxidil [Prescribing Information]. Kelambakkam, Tamil Nadu: Par Formulations Private Limited; 2023. [Accessed 18 Jul. 2023]. (online) Available from:External Link
  8. Badri T, Nessel TA, Kumar DD. Minoxidil. [Updated 2023 Feb 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan. [Accessed 18 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Apple Therapeutics Pvt Ltd
Address: 608, Siddhartha Building- 96, Nehru Place, New Delhi-110019
Country of origin: India

MRP
260
Inclusive of all taxes
60.0 ml in 1 bottle
SOLD OUT

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.