Topep-IV Injection
Prescription Required
Product introduction
Topep-IV Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.
Topep-IV Injection relieves heartburn and helps in healing ulcers.
Topep-IV Injection relieves heartburn and helps in healing ulcers.
Uses of Topep Powder for Injection
- Treatment of Gastroesophageal reflux disease (Acid reflux)
- Treatment of Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Benefits of Topep Powder for Injection
In Treatment of Gastroesophageal reflux disease (Acid reflux)
GERD is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Topep-IV Injection belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
In Treatment of Peptic ulcer disease
Topep-IV Injection belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
In Treatment of Zollinger-Ellison syndrome
Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Topep-IV Injection By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
Side effects of Topep Powder for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topep
- Diarrhea
- Flatulence
- Headache
- Joint pain
- Nausea
- Stomach pain
- Vomiting
- Dizziness
- Thrombophlebitis
How to use Topep Powder for Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Topep Powder for Injection works
Topep-IV Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Topep-IV Injection.
Pregnancy
CONSULT YOUR DOCTOR
Topep-IV Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Topep-IV Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Topep-IV Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Topep-IV Injection is safe to use in patients with kidney disease. No dose adjustment of Topep-IV Injection is recommended.
Liver
CAUTION
Topep-IV Injection should be used with caution in patients with severe liver disease. Dose adjustment of Topep-IV Injection may be needed. Please consult your doctor.
What if you forget to take Topep Powder for Injection?
If you miss a dose of Topep-IV Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Topep-IV Injection
₹56.0/Powder for Injection
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Quick tips
- It is given as an injection into the veins under the supervision of the doctor.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Long-term use of Topep-IV Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Fact Box
Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton pump inhibitors
Patient concerns
FAQs
What is Topep-IV Injection used for?
Topep-IV Injection is used for the treatment of peptic ulcer disease, reflux esophagitis or gastroesophageal reflux disease (GERD). Topep-IV Injection prevents acidity associated with use of painkillers. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms.
Can I take antacids along with Topep-IV Injection?
Yes, you can take antacids along with Topep-IV Injection. Take it 2 hours before or after you take Topep-IV Injection.
How long does it take for Topep-IV Injection to work?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Topep-IV Injection to work properly so you may still have some symptoms during this time.
Does Topep-IV Injection cause weight gain?
Although rare but long-term treatment with Topep-IV Injection may cause weight gain. The reason could be the relief from reflux symptoms which could make you eat more. Consult your doctor for any weight-related concern.
Can I take alcohol with Topep-IV Injection?
No, alcohol intake is not advised with Topep-IV Injection. Alcohol itself does not affect the working of Topep-IV Injection, but it can increase the acid production. This may further cause worsening of your symptoms.
What dietary changes should I make to get relief from acidity?
Topep-IV Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
Can I take Topep-IV Injection for a long term?
Topep-IV Injection is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Topep-IV Injection may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Topep-IV Injection as advised by your doctor and under their supervision.
Are painkillers safe to take along with Topep-IV Injection?
Yes, it is safe to take painkillers along with Topep-IV Injection. Topep-IV Injection prevents acidity and stomach ulcers associated with the intake of painkillers. Topep-IV Injection is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.
Is a single dose of Topep-IV Injection sufficient?
No, a single dose may not be sufficient. However, with only a few doses of Topep-IV Injection you may get relief with the symptoms. Topep-IV Injection is usually needed only for a short term or upto 2 weeks for heartburn, indigestion, acid reflux. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Topep-IV Injection may be prescribed for a long term duration as well. Please consult your doctor if you do not feel better even after taking Topep-IV Injection regularly for 2 weeks as prescribed.
What are the long term side effects of Topep-IV Injection?
If Topep-IV Injection is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:
- Pantoprazole. Philadelphia, PA: Wyeth Laboratories; [Accessed on 28 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Pantoprazole. [Accessed 28 Mar. 2019] (online) Available from:
- Pantoprazole [Product Information]. Sydney, Australia: Takeda Pharmaceuticals Australia Pty Ltd.; 2022. [Accessed 03 Aug. 2023] (online) Available from:
Marketer details
Name: Totem Biotech Pvt Ltd
Address: a-81, corporate house, sarkhej - gandhinagar hwy, bodakdev, ahmedabad, gujarat 380054
Country of origin: India
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MRP
₹56
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1.0 Powder for Injection in 1 vial
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