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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Siphene -M Tablet

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Product introduction

Siphene -M Tablet is a medicine used to treat male and female infertility. In males, it stimulates hormone production, leading to increased sperm production and improved fertility. Additionally, it may help women who are unable to become pregnant, due to ovulation problems or polycystic ovary syndrome (PCOS).

Siphene -M Tablet is used for some types of infertility, in women who are not ovulating properly.

Benefits of Siphene Tablet

In Treatment of Male infertility

Clomiphene helps in the treatment of male infertility by stimulating the production of some hormones that promote the development and release of mature sperm. These hormones play a crucial role in the testes’ function and sperm production. Enhancing hormone levels helps the testes to produce more sperm, resulting in a higher sperm count. This improves the chances of successful conception for couples struggling with male infertility issues.

In Treatment of Female infertility

Siphene -M Tablet helps in the normal development of an egg in a woman’s ovary (female reproductive organ) and stimulates the release of a healthy, matured egg. This helps to treat infertility in women and increases the chance of a successful pregnancy. It is commonly used in women who are taking treatment for ovulation-related issues or polycystic ovary syndrome (PCOS). Take this medicine in the dose and duration prescribed by the doctor.

Side effects of Siphene Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siphene

  • Headache
  • Dizziness
  • Breast enlargement in male
  • Breast pain
  • Vasomotor flushing
  • Enlarged ovary
  • Gastrointestinal disturbance

How to use Siphene Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siphene -M Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Siphene Tablet works

Siphene -M Tablet increases the release of two hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In females, the increased FSH and LH levels stimulate the growth and maturation of eggs (ovarian follicles), ultimately leading to ovulation. In males, these hormones play a crucial role in stimulating the testes to produce more testosterone and enhance sperm production. Production of good sperm and ovulation is crucial for fertility.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Siphene -M Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Siphene -M Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Siphene -M Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Siphene -M Tablet may cause side effects which could affect your ability to drive.
Visual disturbances or dizziness might occur and should avoid engaging in activities requiring full concentration until the effects are better understood.
Kidney
CAUTION
Siphene -M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Siphene -M Tablet may be needed. Please consult your doctor.
Liver
UNSAFE
Siphene -M Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Siphene Tablet?

If you miss a dose of Siphene -M Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Siphene -M Tablet
₹5.72/Tablet
Fertyl-M Tablet
Ar-Ex Laboratories Pvt Ltd
₹6.73/tablet
18% costlier
Clofert Max Tablet
Maneesh Pharmaceuticals Ltd
₹20.94/tablet
266% costlier
₹7.65/tablet
34% costlier
Clofert 25 Tablet
Maneesh Pharmaceuticals Ltd
₹8.76/tablet
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₹8.91/tablet
56% costlier

Quick tips

  • If you are male and taking Siphene -M Tablet, your doctor may recommend semen analysis tests during the treatment.
  • Follow your doctor's instructions regarding the dosage and schedule for taking Siphene -M Tablet.
  • If you are using Siphene -M Tablet for ovulation induction, your doctor may recommend tracking ovulation at home using ovulation predictor kits or monitoring body temperature. This can help you plan intercourse or any fertility treatments.
  • Clomiphene treatment is often limited to a specific number of cycles. If pregnancy does not occur after a certain number of cycles, your healthcare provider may explore other fertility treatments or interventions.

Fact Box

Chemical Class
Triphenyl Ethylene Stilbene Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Partial estrogen agonist

Patient concerns

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I have been on mbcn69 tablet for 6 months, also tried siphene 50 and 100 for 3-4 cycles but have not conceived. Follicles? not developing. I have a 5 year old daughter normally.
Dr. Suman Rao
Obstetrics and Gynaecology
You can try inj for follicular development. Consult an infertility specialist
Treatment for male infertility
Dr. Asmita Kaundal
Obstetrics and Gynaecology
its a vast topic treatment depends on the cause . kindly see an andrologist for detailed evaluation
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Schimmer BP, Parker KL. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1841-43.
  2. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 718-19.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 296-98.
  4. Mbi Feh MK, Wadhwa R. Clomiphene. [Updated 2022 Jun 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 25 Aug. 2023]. (online) Available from:External Link
  5. Da Ros CT, Averbeck MA. Twenty-five milligrams of clomiphene citrate presents positive effect on treatment of male testosterone deficiency - a prospective study. Int Braz J Urol. 2012;38(4):512-8. [Accessed 25 Aug. 2023]. (online) Available from:External Link
  6. Clomiphene. Bridgewater, New Jersey: Sanofi-Aventis U.S.; 2012. [Accessed 25 Aug. 2023] (online) Available from:External Link

Marketer details

Name: Serum Institute Of India Ltd
Address: 212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India
Country of origin: India

MRP
171.55
Inclusive of all taxes
30.0 tablets in 1 packet
SOLD OUT
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