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MD Pharmacology, MBBS
Last updated
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R-Cinex Z Tablet


Introduction of R-Cinex Z Tablet

R-Cinex Z Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

R-Cinex Z Tablet is a combination of isoniazid, pyrazinamide, and rifampicin.

Uses of R-Cinex Z Tablet

Benefits of R-Cinex Z Tablet

In Tuberculosis (TB)

R-Cinex Z Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctorโ€™s instructions carefully to get maximum benefit.

Side effects of R-Cinex Z Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโ€™re worried about them

Common side effects of R-Cinex Z

  • Nausea
  • Vomiting
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Abdominal pain
  • Skin rash
  • Hepatitis (viral infection of liver)
  • Lethargy
  • Low blood platelets
  • Thrombocytopenic purpura
  • Cutaneous reactions

How to use R-Cinex Z Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. R-Cinex Z Tablet is to be taken empty stomach.
Avoid R-Cinex Z Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking R-Cinex Z Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
R-Cinex Z Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
R-Cinex Z Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
R-Cinex Z Tablet may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
R-Cinex Z Tablet should be used with caution in patients with kidney disease. Dose adjustment of R-Cinex Z Tablet may be needed. Please consult your doctor.
Liver
CAUTION
R-Cinex Z Tablet should be used with caution in patients with liver disease. Dose adjustment of R-Cinex Z Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
R-Cinex Z Tablet
โ‚น7.6/Tablet
Macox-ZH Tablet
Macleods Pharmaceuticals Pvt Ltd
โ‚น8.87/tablet
17% costlier
โ‚น1.02/tablet
87% cheaper
โ‚น5.3/tablet
30% cheaper
โ‚น45.94/tablet
504% costlier
Coxbact 3 Forte Tablet
Alpic Remedies Ltd
โ‚น8/tablet
5% costlier

Quick tips

R-Cinex Z Tablet

  • R-Cinex Z Tablet should be taken on an empty stomach but at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how R-Cinex Z Tablet affects you.
  • Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
  • Avoid taking hormone-based birth control methods as R-Cinex Z Tablet may decrease their effectiveness.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

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After having tuberculosis diagnosed she has been recommended to have R cinex EZ 2 tablets daily for 2 months then after 1tablet Risorine for 1 month and now doctor has recommended onceagain to have R cinex EZ 2tables on alternate days what to do.
Dr. Anshum Aneja Arora
Pulmonology
TB treatment is in 2 phases1. Intensive phase where tabs RHZE are given as in your case and in the second phase called continuation phase one one the medicines is stopped nad others continued.Please discuss with your doctor or see another doctor nearby for opinion since , the treatment may have to be modified, read about TB at http://www.arohealth.com/pulmonary-tuberculosis/
I am on ATT for TB treatment from 22 June 2016. Prescribed medicines are R-cinex 600mg, Pzide 1500mg, combutol 1200mg. Doctor has also prescribed Benadon tablet 20mg, rabloc tablet 20mg. I am having rabloc & R-cinex in early morning 5:30 am (empty stomach) & after light breakfast all the remaining tablets. How & when should I take my medicines so that one tablet doesn't contradict other? My liver ALT(SGPT) shot up to 149 on 1 july. asked to stop R-cinex till SGPT doesn't come down. I am want to know which tablet should be taken at which time i.e empty stomach/after light breakfast/lunch? Please help me out here!
Dr. Sfurti Mann
Diabetology
U are taking it correctly.It harms liver sometimes and therefore stopped and re started graduallyU can continue as per your doctor's advise
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References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from:External Link

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Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India

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