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R-Cinex 100 mg/100 mg Tablet


Introduction of R-Cinex Tablet

R-Cinex 100 mg/100 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

R-Cinex 100 mg/100 mg Tablet is a combination of rifampicin and isoniazid.

Uses of R-Cinex Tablet

Benefits of R-Cinex Tablet

In Treatment of Tuberculosis (TB)

R-Cinex 100 mg/100 mg Tablet is a combination of medicines that is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of R-Cinex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of R-Cinex

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use R-Cinex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. R-Cinex 100 mg/100 mg Tablet is to be taken empty stomach.
Avoid R-Cinex 100 mg/100 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking R-Cinex 100 mg/100 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
R-Cinex 100 mg/100 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
R-Cinex 100 mg/100 mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
R-Cinex 100 mg/100 mg Tablet may cause side effects which could affect your ability to drive.
R-Cinex 100 mg/100 mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
CAUTION
R-Cinex 100 mg/100 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of R-Cinex 100 mg/100 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
R-Cinex 100 mg/100 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of R-Cinex 100 mg/100 mg Tablet may be needed. Please consult your doctor.
Use of R-Cinex 100 mg/100 mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take R-Cinex Tablet?

If you miss a dose of R-Cinex 100 mg/100 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
R-Cinex 100 mg/100 mg Tablet
₹2.54/Tablet
RF Kid B6 100 mg/100 mg Tablet
Sunij Pharma Pvt Ltd
₹1.5/tablet
41% cheaper
₹1.6/tablet
37% cheaper
₹5.08/tablet
99% costlier
Anticox II Kid 100 mg/100 mg Tablet
Torrent Pharmaceuticals Ltd
₹1.49/tablet
42% cheaper
₹1.45/tablet
43% cheaper

Quick tips

R-Cinex Tablet

  • You have been prescribed R-Cinex 100 mg/100 mg Tablet for the treatment of tuberculosis.
  • Finish the full course of the medication, even if you feel better. Stopping it early may make the infection come back.
  • Take it on an empty stomach, preferably at the same time everyday.
  • It may discolour your urine, sweat, saliva and tears a reddish-orange colour. This is normal and not harmful.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking R-Cinex 100 mg/100 mg Tablet as this may increase the risk of side effects on the liver.
  • Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking R-Cinex 100 mg/100 mg Tablet as it may make hormonal contraceptives such as the pill less effective.
  • Do not take indigestion remedies (antacids)  within at least two hours of taking R-Cinex 100 mg/100 mg Tablet.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

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After having tuberculosis diagnosed she has been recommended to have R cinex EZ 2 tablets daily for 2 months then after 1tablet Risorine for 1 month and now doctor has recommended onceagain to have R cinex EZ 2tables on alternate days what to do.
Dr. Anshum Aneja Arora
Pulmonology
TB treatment is in 2 phases1. Intensive phase where tabs RHZE are given as in your case and in the second phase called continuation phase one one the medicines is stopped nad others continued.Please discuss with your doctor or see another doctor nearby for opinion since , the treatment may have to be modified, read about TB at http://www.arohealth.com/pulmonary-tuberculosis/
I am on ATT for TB treatment from 22 June 2016. Prescribed medicines are R-cinex 600mg, Pzide 1500mg, combutol 1200mg. Doctor has also prescribed Benadon tablet 20mg, rabloc tablet 20mg. I am having rabloc & R-cinex in early morning 5:30 am (empty stomach) & after light breakfast all the remaining tablets. How & when should I take my medicines so that one tablet doesn't contradict other? My liver ALT(SGPT) shot up to 149 on 1 july. asked to stop R-cinex till SGPT doesn't come down. I am want to know which tablet should be taken at which time i.e empty stomach/after light breakfast/lunch? Please help me out here!
Dr. Sfurti Mann
Diabetology
U are taking it correctly.It harms liver sometimes and therefore stopped and re started graduallyU can continue as per your doctor's advise
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User feedback


FAQs

R-Cinex Tablet

What is R-Cinex 100 mg/100 mg Tablet?

R-Cinex 100 mg/100 mg Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.

What is the most important information I should know about the R-Cinex 100 mg/100 mg Tablet?

Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

What is the best time to take R-Cinex 100 mg/100 mg Tablet?

Take R-Cinex 100 mg/100 mg Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Does R-Cinex 100 mg/100 mg Tablet cause change in urine color/turn urine orange?

Yes, R-Cinex 100 mg/100 mg Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.

Does the use of R-Cinex 100 mg/100 mg Tablet make birth control pills ineffective?

Yes, R-Cinex 100 mg/100 mg Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).

What are the instructions for storage and disposal of R-Cinex 100 mg/100 mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Isoniazid/rifampicin. Guildford Surrey: Aventis Pharma Limited; 1999 [revised 12 Mar. 2019]. [Accessed on 10 Apr. 2019] (online) Available from:External Link
  2. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from:External Link

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