Pyrolate Injection is an anticholinergic medication. It is used before or even during an operation to reduce secretions and it even reverses the unwanted effects of certain medicines used during surgery (muscle relaxants). It also helps to treat peptic ulcers when oral medication is not tolerated.

Pyrolate Injection is used to protect against the unwanted effects of some muscle relaxing drugs, before a surgery to reduce saliva secretion and prevent or reduce slow heart beats during surgery

Uses of Pyrolate Injection

General Anaesthesia
Peptic ulcer disease

Benefits of Pyrolate Injection

In General Anaesthesia

Pyrolate Injection is used before and during surgery to reduce secretions of the mouth, throat, or stomach, such as saliva, stomach acid, or to prevent problems related to heart rhythm during anesthesia, intubation, or surgery. It also helps decrease the unwanted effects that may be caused by certain medicines like, neostigmine, pyridostigmine, etc. It is given by a specialist doctor called an anesthetist in a hospital setup.

In Peptic ulcer disease

Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Pyrolate Injection reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer.

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Side effects of Pyrolate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pyrolate

Urinary retention
Blurred vision
Dilatation of pupil
Cycloplegia (paralysis of the ciliary muscle of the eye)
Ocular hyperemia
Slow heart rate
Palpitations
Reduced sweating
Increased heart rate
Increased intraocular pressure

How to use Pyrolate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pyrolate Injection works

This helps dry up secretions (saliva, stomach acid etc.) from glands before surgery, increases a low heart rate and reverses the unwanted effects of certain medicines used during surgery (muscle relaxants and anaesthetics). By lowering stomach acid content, it also helps treat peptic ulcers.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pyrolate Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Pyrolate Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Pyrolate Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Long-term use of Pyrolate Injection might reduce milk production.

Driving

UNSAFE

Pyrolate Injection may cause side effects which could affect your ability to drive.
Pyrolate Injection may affect vision and coordination. This may affect your driving ability.

Kidney

CAUTION

Pyrolate Injection should be used with caution in patients with kidney disease. Dose adjustment of Pyrolate Injection may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Pyrolate Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Pyrolate Injection

₹119.0/Injection

Glyco P 0.2mg Injection

Khandelwal Laboratories Pvt Ltd

₹11.53/injection

90% cheaper

Pyrotroy 0.2mg Injection

Troikaa Pharmaceuticals Ltd

₹14.8/injection

88% cheaper

Glycolate 0.2mg Injection

Harson Laboratories

₹45/injection

62% cheaper

Pyrolin 0.2mg Injection

Celon Laboratories Ltd

₹12.85/injection

89% cheaper

Vagolate 0.2mg Injection

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₹9.25/injection

92% cheaper

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Quick tips

Pyrolate Injection is used before an operation, to reduce saliva and other secretions and to make the stomach contents less acidic.
It may also be used to reduce side effects of muscle-relaxing drugs and to prevent of slowing of heart beat during surgery.
It is given as an injection into a muscle or into a vein.
Use caution while driving or doing anything that requires concentration as Pyrolate Injection may cause dizziness and blurred vision.

Fact Box

Chemical Class

Synthetic Quaternary Ammonium

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Anticholinergic - Anaesthesia

Patient concerns

I am suffering from stomach problems from last 2 months regularly.This is my ultrasound report.Please explain this report in simple words.

Dr. Pushkar Mani

Physician

U having fatty liverAnd probably peptic ulcer

Gastric problems and peptic ulcer

Dr. Sunil Sekhri

Diabetology

please mention your symptoms and not the diagnosis

FAQs

Is Pyrolate Injection a narcotic?

No, Pyrolate Injection is not a narcotic.

Does Pyrolate Injection cause tachycardia?

Yes, Pyrolate Injection has its action on the heart which increases the heart rate (tachycardia). This property of the medication is utilized during surgery to prevent the fall of heart rate due to various other supplemental anesthetic medications.

Can Pyrolate Injection cause constipation?

Yes, Pyrolate Injection can cause constipation because of its action on the intestine. It decreases the intestinal secretions and also decreases the gut motility which can result in constipation.

Does Pyrolate Injection increase blood pressure?

Yes, Pyrolate Injection can sometimes lead to an increase in blood pressure. There are evidences where it has led to increased blood pressure. Therefore, when injected into a patient during a surgery, the heart rate and blood pressure are continuously monitored.

I am on antidepressants currently. Can I take Pyrolate Injection?

Some classes of antidepressant medicines can worsen the side effects of Pyrolate Injection and cause uneasiness for the patient. These antidepressant medicines may include tricyclic antidepressants (amitriptyline or imipramine), phenelzine, tranylcypromine, clozapine, etc. Therefore, do inform your doctor about your previous illness and the medicines you are taking before you take this medication. Your doctor may make the necessary adjustments.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Glycopyrrolate. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation. Glycopyrrolate. [Accessed 28 June 2023]. (online) Available from:
Glycopyrrolate Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2022. [Accessed 28 June 2023]. (online) Available from:

Marketer details

Name: Neon Laboratories Ltd

Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Country of origin: India

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MRP

₹119

Inclusive of all taxes

10.0 ml in 1 vial

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Variants (2)

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