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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Proluton Depot 250mg/ml Injection


Product introduction

Proluton Depot 250mg/ml Injection is used to prevent premature labor in pregnant women in order to reduce the risk of giving birth too early (preterm birth). It prevents miscarriage and lowers the risk of premature birth in women who have had one premature delivery in the past.

It is a progestin.

Uses of Proluton Depot Injection

Benefits of Proluton Depot Injection

In Prevention of Premature Labor

Proluton Depot 250mg/ml Injection is a man-made form of the female hormone called progesterone, that helps lower the risk of delivering the baby too early (premature labor), particularly in women who have had this complication in an earlier pregnancy. Progesterone is a hormone that thickens the lining of the uterus and prepares it for the growth and development of the baby. So, it helps your uterus grow during pregnancy and also prevents any contractions that can otherwise lead to miscarriage.

Side effects of Proluton Depot Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Proluton Depot

  • Injection site pain
  • Injection site swelling
  • Red spots or bumps
  • Rash

How to use Proluton Depot Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Proluton Depot 250mg/ml Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Proluton Depot 250mg/ml Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Proluton Depot 250mg/ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Proluton Depot 250mg/ml Injection does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Proluton Depot 250mg/ml Injection in patients with kidney disease. Please consult your doctor.
This medicine contains progesterone which can cause fluid retention in patients with underlying kidney disease.
Liver
UNSAFE
Proluton Depot 250mg/ml Injection is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Proluton Depot Injection?

If you miss a dose of Proluton Depot 250mg/ml Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Proluton Depot 250mg/ml Injection
₹209.55/Injection
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Cor 9 500mg/2ml Injection
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Gestlance-H 500 Injection
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Duravet 500mg Injection
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Quick tips

  • Proluton Depot 250mg/ml Injection is used in pregnant women to help lower the risk of giving birth too early (preterm birth).
  • It is only given to a woman who has had a preterm delivery in the past.
  • It is not for use in women who are pregnant with more than one baby (twins, triplets, etc.).
  • It is administered only by or under the immediate supervision of your doctor. Your doctor can start giving you the injection every week between 16 and 20 weeks and continue through week 37, or until you deliver.
  • It may affect blood sugar levels. Monitor your blood sugar regularly.
  • Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. These could be symptoms of a serious liver problem.
  • Inform your doctor immediately if you have pain in the chest, groin or legs, difficulty with breathing, sudden severe headache, slurred speech, sudden unexplained shortness of breath, a sudden loss of coordination, or vision changes while using this medicine.

Fact Box

Chemical Class
Gluco/Mineralocorticoids, Progestogins Derivatives
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Progestins (First generation)

Patient concerns

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Please tell me the brand names of projestron inj
Dr. Suman Rao
Obstetrics and Gynaecology
Proluton depot for supporting pregnancyDepot provera for contraception.
Hello dr.i had miscarriage before 6 months it was my first baby now am 14th week pregnent, wanna ask you for how many months should I take progesteron 200 mg
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
It is good till 14 weeks and after that for uterine relaxation take inj proluton depot weekly for two or three months
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User feedback


FAQs

What is Proluton Depot 250mg/ml Injection? What is it used for?

Proluton Depot 250mg/ml Injection is a type of female sex hormone called progesterone. It helps to lower the risk of preterm delivery (early birth) in a pregnant woman, who had delivered a preterm baby in the past.

How and in what dose should I use Proluton Depot 250mg/ml Injection?

Proluton Depot 250mg/ml Injection is given as an injection, by a doctor or trained nurse. The dose will be decided by your doctor, depending on your exact medical condition.

What if I miss a dose of Proluton Depot 250mg/ml Injection?

Ideally, you should try not to miss any dose. However, if you miss a dose consult with your doctor as soon as you remember.

Who should not receive Proluton Depot 250mg/ml Injection?

Proluton Depot 250mg/ml Injection should not be used if you have:<br>-blood clots or other blood clotting problems now or in the past<br>-high blood pressure that is not controlled<br>-liver problems, including liver tumors<br>-breast cancer or other hormone-sensitive cancers now or in the past<br>-unusual vaginal bleeding not related to your current pregnancy<br>-yellowing of your skin due to liver problems during your pregnancy.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 671-72.
  2. Mayo Clinic. Hydroxyprogesterone. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Hydroxyprogesterone. [Accessed 03 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Hydroxyprogesterone Caproate Injection [Package Insert]. Ranipur, Uttarakhand: Akums Drugs & Pharmaceuticals Ltd. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  6. Hydroxyprogesterone Caproate Injection [Prescribing Information]. Waltham, MA: AMAG Pharmaceuticals, Inc.; 2022. [Accessed 05 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India

MRP
209.55
Inclusive of all taxes
1.0 ml in 1 ampoule
SOLD OUT
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