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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Presafe 250mg Injection


Product introduction

Presafe 250mg Injection is used to restore menstrual cycles in women whose periods have stopped. It is a natural female hormone important for regulating ovulation (release of an egg from a woman's ovary) and menstruation. It is used in the treatment of infertility to help you get pregnant.

It is a progesterone.

Benefits of Presafe Injection

In Hormone replacement therapy

Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

In Female infertility

Presafe 250mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Side effects of Presafe Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Presafe

  • Headache
  • Fatigue
  • Joint pain
  • Cough
  • Abnormal menstrual bleeding
  • Musculoskeletal (bone, muscle or joint) pain
  • Slurred speech
  • Pain behind eyes
  • Vertigo

How to use Presafe Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Presafe 250mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Presafe 250mg Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Presafe 250mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Presafe 250mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Presafe 250mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Presafe 250mg Injection in patients with liver disease. Please consult your doctor.
Use of Presafe 250mg Injection is however not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Presafe 250mg Injection
₹54.0/Injection
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Stable 250mg Injection
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Proden Depot 250mg Injection
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Quick tips

  • Presafe 250mg Injection is used in the treatment of female infertility and as a part of hormone replacement therapy.
  • It regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
  • It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
  • It may cause sleepiness or drowsiness. Don't drive or do anything that requires mental focus until you know how Presafe 250mg Injection affects you.
  • It may cause bleeding  or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Fact Box

Chemical Class
Progesterone Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone

Patient concerns

arrow
I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue
Dr. Megha Gupta
Obstetrics and Gynaecology
Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.
I have sexual hormone problem and infertility problem. 30 millions sperm count,motility 50 only.please send me prescription.
Dr. Pranay Gandhi
Sexology
sperm count is normal so is motility. for increasing ur testosterone levels 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effects
arrow

FAQs

What is Presafe 250mg Injection?

Presafe 250mg Injection contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It may also be prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).

What is Presafe 250mg Injection used to treat?

Presafe 250mg Injection is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in women who have had their menses before). It is used to support pregnancy, prevent premature labor, and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.

How and in what dose should I take Presafe 250mg Injection?

Presafe 250mg Injection is to be given by a doctor or nurse only. It is given as an injection into the muscle. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Presafe 250mg Injection.

Does Presafe 250mg Injection cause weight gain?

Yes, the use of Presafe 250mg Injection may cause weight gain. The reason for this weight gain could be water retention, however this may not be a serious sign. If you are concerned about weight gain, contact your doctor.

How is Presafe 250mg Injection beneficial for fertility and pregnancy?

Presafe 250mg Injection consists of progesterone, which is important for fertility. Progesterone is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and also maintain it. Presafe 250mg Injection is given in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

Is Presafe 250mg Injection effective?

Presafe 250mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Presafe 250mg Injection too early, the symptoms may return or worsen.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
  2. Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
  3. Progesterone. Lodi, Italy: IBSA Farmaceutici Italia Srl; 2013. [Accessed 21 Jun. 2019] (online) Available from:External Link
  4. Drugs.com. Progesterone. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Welbe Life Sciences
Address: Desh Bandhu Gupta Road, New Delhi, Delhi
Country of origin: India

MRP
54
Inclusive of all taxes
1.0 ml in 1 vial
SOLD OUT
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