Pirox 20 Capsule
Prescription Required
Product introduction
Pirox 20 Capsule is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles.
It is a non-steroidal anti-inflammatory drug (NSAID).
It is a non-steroidal anti-inflammatory drug (NSAID).
Uses of Pirox Capsule
Benefits of Pirox Capsule
In Pain relief
Pirox 20 Capsule is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Pirox Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pirox
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Pirox Capsule
Take this medicine in the dose and duration as advised by your doctor. Pirox 20 Capsule is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Pirox 20 Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Pirox 20 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pirox 20 Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Pirox 20 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pirox 20 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Pirox 20 Capsule may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Pirox 20 Capsule should be used with caution in patients with liver disease. Dose adjustment of Pirox 20 Capsule may be needed. Please consult your doctor.
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Quick tips
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Pirox 20 Capsule helps relieve pain and swelling of various joints and muscles.
- Take it with food to avoid stomach upset.
- Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
Fact Box
Chemical Class
Enolic acid Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)
Patient concerns
User feedback
Patients taking Pirox 20 Capsule
Once A Day
80%
Twice A Day
20%
What are you using Pirox Capsule for?
Gout
33%
Others
33%
Rheumatoid ar*
17%
Ankylosing sp*
17%
*Rheumatoid arthritis, Ankylosing spondylitis
How much was the improvement?
Average
100%
What were the side-effects while using Pirox 20 Capsule?
No Side Effec*
100%
*No Side Effect
FAQs
What is the difference between Pirox 20 Capsule and diclofenac?
Both Pirox 20 Capsule and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pirox 20 Capsule.
What is the difference between Pirox 20 Capsule and naproxen?
Both Pirox 20 Capsule and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pirox 20 Capsule.
What is the difference between Pirox 20 Capsule and meloxicam?
Both Pirox 20 Capsule and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pirox 20 Capsule.
What is the difference between Pirox 20 Capsule and ketoprofen?
Both Pirox 20 Capsule and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pirox 20 Capsule. Ketoprofen gel also showed excellent tolerability.
What is the difference between Pirox 20 Capsule and tramadol?
Pirox 20 Capsule is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
What is the difference between Pirox 20 Capsule and nimesulide?
Both Pirox 20 Capsule and nimesulide are pain killers. However, Pirox 20 Capsule is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Can Pirox 20 Capsule be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pirox 20 Capsule or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pirox 20 Capsule.
Are Pirox 20 Capsule and aspirin same?
No. Pirox 20 Capsule and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Can Pirox 20 Capsule be used along with dexamethasone?
No. Pirox 20 Capsule should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Can Pirox 20 Capsule be used with methocarbamol?
Yes. Methocarbamol can be used with Pirox 20 Capsule as no serious side effects are known. Inform your doctor before starting any of the medication.
Can Pirox 20 Capsule be used along with paracetamol?
Yes. Paracetamol can be used with Pirox 20 Capsule as no serious side effects are known. Inform your doctor before starting any of the medication.
Is Pirox 20 Capsule a NSAID?
Yes. Pirox 20 Capsule is a non-steroidal anti-inflammatory drug (NSAID).
Is Pirox 20 Capsule a sulfa drug?
Pirox 20 Capsule is a sulphur containing compound. Pirox 20 Capsule can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Is Pirox 20 Capsule a blood thinner?
No. Pirox 20 Capsule is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Is Pirox 20 Capsule a muscle relaxant?
No. Pirox 20 Capsule is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Is Pirox 20 Capsule a narcotic?
No. Pirox 20 Capsule is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Can Pirox 20 Capsule be used in hypertension?
No. Pirox 20 Capsule is not a medication to control hypertension. It is important to note that Pirox 20 Capsule decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pirox 20 Capsule.
Can Pirox 20 Capsule be used along with Losartan?
No. Pirox 20 Capsule should not be combined with Losartan. It is important to note that Pirox 20 Capsule decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirox 20 Capsule.
Can Pirox 20 Capsule be used with Lisinopril?
No. Pirox 20 Capsule should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirox 20 Capsule.
Can Pirox 20 Capsule be used with calcium channel blocker?
Yes. Pirox 20 Capsule can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Can Pirox 20 Capsule be used with Tizanidine?
Yes, Pirox 20 Capsule can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Why is beta cyclodextrin added to Pirox 20 Capsule?
Yes. Pirox 20 Capsule can be combined with beta-cyclodextrin. Research has shown that combining Pirox 20 Capsule with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Are there any alternatives of Pirox 20 Capsule?
Yes. There are alternatives to Pirox 20 Capsule. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
What are the contraindications for Pirox 20 Capsule?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Can Pirox 20 Capsule be used in the treatment of allergy?
No. Pirox 20 Capsule is not a drug to treat allergy. It is a pain killer.
How long does Pirox 20 Capsule work?
Pirox 20 Capsule is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Can you get high by using Pirox 20 Capsule?
No. Pirox 20 Capsule is not known to cause high. It is a non-narcotic painkiller.
Can Pirox 20 Capsule be used to treat menstrual cramp?
Pirox 20 Capsule is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Can I use Pirox 20 Capsule for a migraine?
Pirox 20 Capsule is not approved for the treatment of migraine. Research studies have shown that Pirox 20 Capsule is effective in significantly decreasing the pain associated with migraine without aura.
Is Pirox 20 Capsule effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pirox 20 Capsule as the cause of back pain can be different for different person.
Is Pirox 20 Capsule affective in gout management?
Yes. Pirox 20 Capsule can be given for the treatment of acute gout. Research studies have shown Pirox 20 Capsule to be highly effective in the treatment of acute gout.
Can you donate blood when on the medication with Pirox 20 Capsule?
Yes. You can donate blood when on Pirox 20 Capsule. Do inform your doctor before donating blood.
Can I use Pirox 20 Capsule if I am a diabetic?
Pirox 20 Capsule in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirox 20 Capsule so taking piroxicam can lead to increased risk of renal failure by many folds.
Can I use Pirox 20 Capsule if I have a deranged renal function?
No. Pirox 20 Capsule should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Can Pirox 20 Capsule lead to skin reactions?
Yes. Pirox 20 Capsule is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Can I use Pirox 20 Capsule if I am pregnant?
No. Pirox 20 Capsule should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Can I use Pirox 20 Capsule if I have peptic ulcer disease?
No. Pirox 20 Capsule is contraindicated in cases of active peptic ulcer disease. Pirox 20 Capsule is known to cause gastric ulceration and bleeding.
Can I use Pirox 20 Capsule if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Can Pirox 20 Capsule lead to difficulty in conception?
Yes. Pirox 20 Capsule can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Can Pirox 20 Capsule be used with diuretics?
No. Pirox 20 Capsule should not be used with diuretics. Pirox 20 Capsule reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Can Pirox 20 Capsule be used with lithium?
No. Pirox 20 Capsule should not be used with lithium. Pirox 20 Capsule leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Can Pirox 20 Capsule be used with warfarin?
No. Pirox 20 Capsule should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
What increases the chances of getting a gastric ulcer when I am already taking Pirox 20 Capsule?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirox 20 Capsule?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
What are the serious side effects of Pirox 20 Capsule?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
- PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:
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- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
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Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
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