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Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:15 PM (IST)

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Perisafe 2mg Syrup


Product introduction

Perisafe 2mg Syrup is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.

Perisafe 2mg Syrup is used to prevent and treat nausea and vomiting.

Benefits of Perisafe Syrup

In Treatment of Nausea

Chemotherapy, radiotherapy, major surgeries, and abdominal infection put your child at risk of developing severe nausea and vomiting. It happens due to the release of a chemical called serotonin. Perisafe 2mg Syrup acts by blocking the effect of this chemical and prevents nausea and vomiting. It also helps your child to recover more comfortably from these treatments. Stick to the prescribed dose, time, and way, and do not increase or decrease the dose by yourself without consulting your child’s doctor as it may result in side effects.

Side effects of Perisafe Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Perisafe

  • Headache
  • Constipation
  • Diarrhea
  • Fatigue

How to use Perisafe Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Perisafe 2mg Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Perisafe Syrup works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Perisafe 2mg Syrup just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Safety advice

Alcohol
SAFE
Consuming alcohol with Perisafe 2mg Syrup does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Perisafe 2mg Syrup is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Perisafe 2mg Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Perisafe 2mg Syrup does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Perisafe 2mg Syrup is safe to use in patients with kidney disease. No dose adjustment of Perisafe 2mg Syrup is recommended.
Liver
CAUTION
Perisafe 2mg Syrup should be used with caution in patients with liver disease. Dose adjustment of Perisafe 2mg Syrup may be needed. Please consult your doctor.

What if you forget to take Perisafe Syrup?

Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Perisafe 2mg Syrup
₹36.0/Syrup
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Quick tips

  • Perisafe 2mg Syrup effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
  • It is fast-acting and starts working within 30 minutes.
  • Practice self-care measures:
    1. Give plenty of fluids to your child to avoid dehydration
    2. Avoid giving fried and spicy food or heavy meals to your child. 
    3. Ensure that your child eats slowly and in small proportions.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin antagonists (5-HT3 antagonists)

Patient concerns

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What is side effect of primolut n
Dr. Megha Gupta
Obstetrics and Gynaecology
Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
Vomiting, nausea neck pain backside
Dr. Vijay Verma
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Neck pain may be due to nausea NAD vomiting Visit physician for the same
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FAQs

What is Perisafe 2mg Syrup used for?

Perisafe 2mg Syrup is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Perisafe 2mg Syrup to your child to prevent vomiting post-procedure. Apart from this, Perisafe 2mg Syrup is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Perisafe 2mg Syrup to your child for a few days. Stick to the dose for best results.

What if my child takes too much Perisafe 2mg Syrup?

Perisafe 2mg Syrup is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Perisafe 2mg Syrup can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.

How should Perisafe 2mg Syrup be stored?

Perisafe 2mg Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.

What all medicines should my child avoid while taking Perisafe 2mg Syrup?

Usually, it is advised not to give Perisafe 2mg Syrup along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.

In what conditions do I need to call my child’s doctor right away?

Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.

My child is having a migraine and is on medication. Can I give Perisafe 2mg Syrup along with it?

Avoid combining Perisafe 2mg Syrup with such medicines because concomitant use of Perisafe 2mg Syrup with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:External Link
  2. Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:External Link

Marketer details

Name: Assign Drug Industries Pvt Ltd
Address: FIRST FLOOR, CORPORATION BANK, SULTANPUR Sultanpur UP 228001 IN
Country of origin: India

MRP
36
Inclusive of all taxes
30.0 ml in 1 bottle
SOLD OUT

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