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MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Onstart Injection


Product introduction

Onstart Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Onstart Injection is used to prevent and treat nausea and vomiting.

Uses of Onstart Injection

Benefits of Onstart Injection

In Treatment of Nausea

Onstart Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Side effects of Onstart Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Onstart

  • Injection site pain
  • Constipation
  • Diarrhea
  • Fatigue
  • Headache

How to use Onstart Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
SAFE
Consuming alcohol with Onstart Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Onstart Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Onstart Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Onstart Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Onstart Injection is safe to use in patients with kidney disease. No dose adjustment of Onstart Injection is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Onstart Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Onstart Injection
₹10.37/Injection
Medsetron Injection
Medley Pharmaceuticals
₹3.03/injection
71% cheaper
Emiron Injection
Medinova Labs
₹18.45/injection
78% costlier
Danset Injection
Ceras Pharmaceutical
₹16.8/injection
62% costlier
Ondot Injection
Glorious Biotech
₹17.13/injection
65% costlier
Onmed Injection
Medoz Pharmaceutical Pvt. Ltd
₹20/injection
93% costlier

Quick tips

  • You have been prescribed Onstart Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It is given as an injection into veins or as drip under the supervision of a doctor.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
  • It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin antagonists (5-HT3 antagonists)

Patient concerns

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Dr. Megha Gupta
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Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
Vomiting, nausea neck pain backside
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Neck pain may be due to nausea NAD vomiting Visit physician for the same
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FAQs

How quickly does Onstart Injection work?

Onstart Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

What are the side effects of Onstart Injection?

The most common side effects of Onstart Injection are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Is Onstart Injection a steroid?

No, Onstart Injection is an antiemetic and not a steroid. Onstart Injection is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Does Onstart Injection work for seasickness?

No, Onstart Injection does not work for seasickness. This is because Onstart Injection has very little effect on the nausea associated with motion sickness.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. MedlinePlus. Ondansetron. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Punjab Formulations Ltd
Address: 339, LAXMI PLAZA, LAXMI INDUSTRIAL ESTATE, NEW LINK ROAD, ANDHERI (WEST) MUMBAI MH 400053 IN , - , .
Country of origin: India

MRP
10.37
Inclusive of all taxes
2.0 ml in 1 vial
SOLD OUT

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