Nurestat-Plus Tablet SR is a medicine used in the treatment of diabetic nerve disease. It protect the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.

Nurestat-Plus Tablet SR may be taken with or without food, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

The most common side effects of this medicine include nausea, vomiting, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.

Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.

Uses of Nurestat-Plus Tablet SR

Diabetic nerve pain

Benefits of Nurestat-Plus Tablet SR

In Diabetic nerve pain

Nurestat-Plus Tablet SR is a medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and also improves nerve conduction. Taking Nurestat-Plus Tablet SR regularly will improve your physical and social functioning and overall quality of life.

Side effects of Nurestat-Plus Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nurestat-Plus

Nausea
Vomiting
Increased liver enzymes

How to use Nurestat-Plus Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nurestat-Plus Tablet SR may be taken with or without food, but it is better to take it at a fixed time.

How Nurestat-Plus Tablet SR works

Nurestat-Plus Tablet SR is a combination of two medicines: Epalrestat and methylcobalamin which treat diabetic nerve disease. Epalrestat is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related in causing diabetic nerve disease. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nurestat-Plus Tablet SR.

Pregnancy

CONSULT YOUR DOCTOR

Nurestat-Plus Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nurestat-Plus Tablet SR during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nurestat-Plus Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Nurestat-Plus Tablet SR in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Nurestat-Plus Tablet SR in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nurestat-Plus Tablet SR

₹33.9/Tablet SR

Epineuron SR Tablet

Aristo Pharmaceuticals Pvt Ltd

₹21.57/tablet sr

31% cheaper

Aldonil Plus Tablet SR

Zydus Cadila

₹28.03/tablet sr

10% cheaper

Alrista Plus Tablet SR

Macleods Pharmaceuticals Pvt Ltd

₹20.79/tablet sr

33% cheaper

Epalrica-M Tablet SR

Ordain Health Care Global Pvt Ltd

₹25.21/tablet sr

19% cheaper

Epalpex-M SR Tablet

Shilpex Pharmysis

₹26.25/tablet sr

16% cheaper

Quick tips

Take it only as per the dose and duration prescribed by your doctor.
Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
Inform your doctor if you have:
- Cut or sore on your feet that is infectious or not healing
- Burning or tingling sensation in arm or feet that hamper your routine activities
- Trouble in digestion, urination, or sexual functioning
- Dizziness
To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
Monitor your blood sugar level regularly.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Which is best tablet for diabetic patient either glucocorticoid-G plus 1 or glyciphage SR 1 mg Which is best tablet for type2 diabetic patient either gluconorm-G plus 1 or glyciphage SR 1 mg Am taking one tablet half an hour before the breakfast and before the dinner presently. Is it correct time to take?

Dr. Ashwin Porwal

Internal Medicine

it depends on patient to patient

Ensure plus for diabetic patient

Dr. Tapas Kumbhkar

Internal Medicine

I don't know about this

Related lab tests

Glycosylated Hemoglobin

Top Diabetologists

Dr. Ambrish Mithal

MBBS, MD, DM

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-35. [Accecssed 08 Apr. 2019] (online) Available from:
National Institues of Health. Vitamin B12. [Accessed 08 Apr. 2019] (online) Available from:
Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 08 Apr. 2019] (online) Available from:

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.