Author Details
Written By
MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Nitrofirst 10mg Tablet


Product introduction

Nitrofirst 10mg Tablet is used to prevent heart-related chest pain (angina). It works by relaxing and widening blood vessels so blood can flow more easily to the heart. This medicine will not treat an angina attack that has already begun.

Nitrofirst 10mg Tablet is used to treat chest pain and also to promote healing of skin tear in the back passage

Benefits of Nitrofirst Tablet

In Prevention of Angina (heart-related chest pain)

Nitrofirst 10mg Tablet reduces your risk of getting heart-related chest pain (angina attack). It does not treat an angina attack that has already begun and should not be used for this purpose. It works by relaxing and widening blood vessels in the heart. This makes it easier for blood to flow to the heart, so it gets more oxygen. This medicine thus helps to increase your ability to exercise and go about your daily life more easily and confidently. It should be taken regularly to be effective.

Side effects of Nitrofirst Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nitrofirst

  • Headache
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Upper respiratory tract infection
  • Abdominal pain
  • Allergic reaction
  • Chest pain
  • Diarrhea

How to use Nitrofirst Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nitrofirst 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nitrofirst Tablet works

Nitrofirst 10mg Tablet is a nitrate. It dilates peripheral arteries and veins. Dilation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing workload of heart. As a result, the heart muscle does not need as much blood and oxygen supply.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Nitrofirst 10mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Nitrofirst 10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Nitrofirst 10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Nitrofirst 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Nitrofirst 10mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Nitrofirst 10mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver
SAFE IF PRESCRIBED
Nitrofirst 10mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nitrofirst 10mg Tablet may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Nitrofirst 10mg Tablet
₹1.81/Tablet
Monotrate 10 Tablet
Sun Pharmaceutical Industries Ltd
₹1.1/tablet
39% cheaper
₹2.12/tablet
17% costlier
Monit 10 Tablet
Intas Pharmaceuticals Ltd
₹2.21/tablet
22% costlier
Nitrofix 10 Tablet
Micro Labs Ltd
₹2.19/tablet
21% costlier
₹2.19/tablet
21% costlier

Quick tips

  • You have been prescribed Nitrofirst 10mg Tablet for the prevention and treatment of heart-related chest pain (angina).
  • Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
  • Nitrofirst 10mg Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Do not consume alcohol while taking Nitrofirst 10mg Tablet as it may cause increased dizziness.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • You may develop tolerance to Nitrofirst 10mg Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrofirst 10mg Tablet as it may cause low blood pressure.

Fact Box

Chemical Class
Nitrates
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
NO Donors

Patient concerns

arrow
What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
Interventional Cardiology
Related to chest pain angina commonly
Chest pain headache vetrigo Angina pain
Dr. Nabajit Talukdar
Interventional Cardiology
Get echo n ECG done
arrow

User feedback


FAQs

Does Nitrofirst 10mg Tablet affect heart rate?

Yes, Nitrofirst 10mg Tablet may affect the heart rate. Nitrofirst 10mg Tablet causes a decrease in blood pressure. This decrease in blood pressure further causes a decrease in the heart rate (bradycardia). In some cases, it may also cause an increase in the heart rate (tachycardia). Consult your doctor in case you do not feel well after taking this medicine or if you notice a change in your heart rate.

What if I forget to take a dose of Nitrofirst 10mg Tablet?

You can take the forgotten dose of Nitrofirst 10mg Tablet if you remember it within 12 hours. However, if you remember it after 12 hours of the scheduled time, then skip the missed dose and continue with the next dose.

Can I stop taking Nitrofirst 10mg Tablet after sometime?

No, do not stop taking this medicine without talking to your doctor. Stopping it suddenly may increase your chances of having an anginal attack. If you have any concerns regarding Nitrofirst 10mg Tablet consult your doctor.

What are the symptoms of an overdose of Nitrofirst 10mg Tablet?

Taking more than the recommended dose of Nitrofirst 10mg Tablet may cause throbbing headache, reddening of the skin, chills along with sweating, nausea, vomiting, and a fast heartbeat. Seek emergency help and consult your doctor immediately if you take more than the recommended dose of this medicine.

Can Nitrofirst 10mg Tablet be taken at night?

Depending upon the dose, your doctor may recommend you to take this medicine once or twice daily. When a single dose is recommended, then it is preferred to be taken in the morning. If taking it twice a day, maintain a gap of 7 hours between the two doses. This helps decrease the chances of Nitrofirst 10mg Tablet becoming ineffective (tolerance) after some time.

Does Nitrofirst 10mg Tablet lower BP?

Yes, Nitrofirst 10mg Tablet can cause a fall in blood pressure. This medicine widens the blood vessels and decreases the resistance in them, causing a fall in blood pressure. This fall in blood pressure may in turn decrease the heartbeat which can lead to angina. This medicine should be avoided in people who already have low blood pressure. Discuss with your doctor if you have any concerns.

Can I take sildenafil while taking Nitrofirst 10mg Tablet?

No, you should not take sildenafil along with Nitrofirst 10mg Tablet. Both these medicines lower blood pressure and belong to the same class. Taking these two medicines together may cause a severe decrease in blood pressure, fainting, and even a heart attack. Along with this, also avoid taking other medicines belonging to similar classes such as vardenafil and tadalafil.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 47.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 744.
  3. Drugs.com. Isosorbide mononitrate Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation. Isosorbide Mononitrate. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  6. National Health Services. Isosorbide mononitrate and isosorbide dinitrate. [last Reviewed: 1 Jul. 2021]. [Accessed 05 Jul. 2023]. (online) Available from:External Link
  7. Isosorbide mononitrate tablet [Prescribing Information]. Dupnitsa, Bulgaria: Balkanpharma - Dupnitsa AD; 2022. [Accessed 05 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Zyphar's Pharmaceuticals Pvt Ltd
Address: 102/103, Park Plaza, Opp. Kamla Nehru Park, Off. Bhandarkar Road, Pune - 411004, Maharashtra (India)
Country of origin: India

MRP
18.1
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.