Nigrain 20mg Tablet helps decrease anxiety and relieve tremors. It is also used to help prevent migraine, heart-related chest pain (angina), and bleeding in the stomach caused by high blood pressure in the liver (portal hypertension).

Nigrain 20mg Tablet is used to treat chest pain (angina), heart failure and high blood pressure.

Uses of Nigrain Tablet

Treatment of Pheochromocytoma
Treatment of Hypertension (high blood pressure)
Prevention of migraine
Treatment of Anxiety
Treatment of Arrhythmia
Prevention of Heart attack
Prevention of Angina (heart-related chest pain)
Treatment of Tremors

Benefits of Nigrain Tablet

In Treatment of Pheochromocytoma

While carrying out surgery for the removal of pheochromocytoma, there is a risk of abnormally high blood pressure. Nigrain 20mg Tablet blocks the effect of some chemicals on your heart and blood vessels. This slows down the heart rate and helps the heartbeat with less force thereby lowering your blood pressure. It is used for the immediate reduction of very high blood pressure (hypertensive emergency). Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.

In Treatment of Hypertension (high blood pressure)

Nigrain 20mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

In Prevention of migraine

Nigrain 20mg Tablet helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

In Treatment of Anxiety

Nigrain 20mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. Nigrain 20mg Tablet will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

In Treatment of Arrhythmia

Nigrain 20mg Tablet is used to stabilize heart rate. It helps in normalizing an abnormal heart rhythm, preventing it occurring in the first place or slowing down the heart rate during an episode.

In Prevention of Heart attack

Nigrain 20mg Tablet helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a heart attack. It can also reduce the risk of dying if it is given immediately after a heart attack. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

In Prevention of Angina (heart-related chest pain)

Nigrain 20mg Tablet relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

In Treatment of Tremors

Nigrain 20mg Tablet helps improve the flow of blood and prevents abnormal activity of muscles that trigger tremors. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.

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Side effects of Nigrain Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nigrain

Tiredness
Weakness
Raynaud's phenomenon
Arrhythmia (irregular heartbeats)
Nausea
Vomiting
Diarrhea

How to use Nigrain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nigrain 20mg Tablet is to be taken empty stomach.
Avoid Nigrain 20mg Tablet with high-fat meals such as olive oil, nuts & seeds (Brazil nuts), dark chocolate, butter and meat.

How Nigrain Tablet works

Nigrain 20mg Tablet contains Propranolol, a beta blocker. It works by affecting the body’s response to nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for the heart to pump blood around the body. This prevents arrhythmias. It also widens the blood vessels in the body for better blood flow, thereby preventing angina as well as migraine. The exact mechanism by which it prevents tremors is not known, but experts believe that Nigrain 20mg Tablet helps block the nerve impulses to the muscles responsible for tremors. Propranolol helps block the effects of the chemical messengers namely, adrenaline and noradrenaline, that are produced by the brain and are responsible for increasing your heart rate which makes you feel anxious. This way it helps with anxiety. While treating pheochromocytoma, Nigrain 20mg Tablet may be given to block the action of high-adrenaline hormones, to lower the risk of developing dangerously high blood pressure during surgery for removing the tumor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nigrain 20mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nigrain 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Nigrain 20mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Nigrain 20mg Tablet may cause side effects which could affect your ability to drive.
Nigrain 20mg Tablet may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

Nigrain 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Nigrain 20mg Tablet is recommended.
However, inform your doctor if you have any kidney disease. Nigrain 20mg Tablet may be started with a low dose and then increased further. Regular monitoring of blood pressure is advisable for dose adjustment.

Liver

CAUTION

Nigrain 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Nigrain 20mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

It is not the first-choice treatment for high blood pressure according to the latest guidelines.
It may hide the symptoms of low blood sugar if you have diabetes. Monitor blood sugar levels regularly.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Nigrain 20mg Tablet can cause dizziness and sleepiness.
Inform your doctor if you notice increased swelling around your legs or ankles, sudden weight gain or sudden shortness of breath as these may be symptoms of heart failure.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Naphthalenes derivatives

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Beta blocker- Non selective

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Interventional Cardiology

Related to chest pain angina commonly

I am having pain in left side of the chest also in left arm is it related to heart attack what can be done get relief ??

Dr. Manju Singh

Homeopathy

Please consult to your nearest doctor for blood pressure examination. then let me know.

I am suffering from anxiety and depression since 2008. I have anxiety about heart attack.

Dr. Jyoti Kapoor Madan

Psychiatry

Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. If the condition is persisting for a long time, it's better to see a psychiatrist.

User feedback

Patients taking Nigrain 20mg Tablet

Twice A Day

77%

Once A Day

23%

What are you using Nigrain Tablet for?

High blood pr*

100%

*High blood pressure

FAQs

My doctor has prescribed Nigrain 20mg Tablet even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?

Yes, it is possible that your doctor prescribed Nigrain 20mg Tablet for chest pain (angina). Nigrain 20mg Tablet is a beta-blocker that is used to lower high blood pressure, prevent angina, treat or prevent heart attacks or reduce your risk of heart problems following a heart attack. Nigrain 20mg Tablet is also used to treat irregularities in the heartbeat, including those caused by anxiety, essential tremor (shaking of the head, chin and hands). It also prevents migraine headaches, overactive thyroid (thyrotoxicosis and hyperthyroidism), and bleeding in the food pipe caused by high blood pressure.

When can I expect relief in my symptoms after starting Nigrain 20mg Tablet for high blood pressure?

Nigrain 20mg Tablet usually starts working within a few hours of taking it. However, it may take up to a week to see the full benefits of the symptoms of high blood pressure or heart conditions. You may not notice any difference, but that does not mean it is not working. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Can Nigrain 20mg Tablet be used in asthmatics?

No, Nigrain 20mg Tablet cannot be used in asthmatics. This is because using Nigrain 20mg Tablet in asthma patients can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any episodes of difficulty breathing, before starting treatment with Nigrain 20mg Tablet.

What if I take an overdose of Nigrain 20mg Tablet?

If you take an overdose of Nigrain 20mg Tablet you may experience symptoms such as slow heartbeat, trembling, difficulty breathing, or dizziness. However, the response of taking too much of Nigrain 20mg Tablet varies from person to person. It would be best to consult a doctor if you think you have taken more than what you are prescribed.

Can I stop taking Nigrain 20mg Tablet as my chest pain is under control?

No, you should not stop taking Nigrain 20mg Tablet suddenly because that may worsen your angina or may cause a heart attack. Tell your doctor and if there is a need to stop Nigrain 20mg Tablet, your doctor will reduce your dose gradually over a period of a few weeks.

Does Nigrain 20mg Tablet relieve anxiety?

Yes, Nigrain 20mg Tablet helps relieve the symptoms of anxiety such as irritability, restlessness, excessive worry, lack of concentration, racing or unwanted thoughts, fatigue, insomnia (lack of sleep), palpitations (irregular heart rate), or trembling. The dose and duration of taking Nigrain 20mg Tablet will be suggested by your doctor, depending on whether your symptoms are a recurring problem or occur only in stressful conditions. However, Nigrain 20mg Tablet is usually given for the short-term treatment of anxiety. If you have any doubts, consult your doctor.

What other lifestyle changes should I make while taking Nigrain 20mg Tablet?

Lifestyle changes play a major role in keeping you healthy if you are taking Nigrain 20mg Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Nigrain 20mg Tablet and to keep yourself healthy.

Is Nigrain 20mg Tablet effective?

Nigrain 20mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Nigrain 20mg Tablet too early, the symptoms may return or worsen.

What if I forget to take a dose of Nigrain 20mg Tablet?

If you forget a dose of Nigrain 20mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Is Nigrain 20mg Tablet safe?

Nigrain 20mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

I have been on Indomethacin for several months. Will it be a problem if I start taking Nigrain 20mg Tablet along with it?

Yes, Indomethacin may interfere with the working of Nigrain 20mg Tablet and make it less effective. As a result, your blood pressure may increase. Speak to your doctor who will prescribe you a different medicine to control blood pressure.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 320.
Opie LH. β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 28-29.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 175-76.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1162-63.
Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

Marketer details

Name: Torrent Pharmaceuticals Ltd

Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Country of origin: India

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