Natfost 500mg Injection
Prescription Required
Product introduction
Natfost 500mg Injection is used to prevent dryness in the mouth after radiotherapy of head and neck cancer. It reduces the harmful effect of chemotherapy on the kidneys during treatment with cisplatin (medicines used to treat cancer).
It is cytoprotective agent
It is cytoprotective agent
Uses of Natfost Injection
Benefits of Natfost Injection
In Treatment of Dryness in the mouth after radiotherapy of head and neck cancer
Natfost 500mg Injection is used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer. It protects the kidneys from harmful effects of the chemotherapy medicine cisplatin in patients that receive this medication for the treatment of ovarian cancer. It is given as an injection by a doctor or nurse and should not be self-administered.
Side effects of Natfost Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Natfost
- Nausea
- Vomiting
- Decreased blood pressure
- Hiccup
- Sleepiness
- Dizziness
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Fever
- Chills
How to use Natfost Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Natfost 500mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Natfost 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Natfost 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Natfost 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Natfost 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Natfost 500mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Natfost 500mg Injection in patients with liver disease. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Natfost 500mg Injection is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
- It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
- You will be monitored for blood pressure before and after every 5 minutes of infusion.
- It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.
Fact Box
Chemical Class
Phosphorylated aminosulfhydryl compound
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Cytoprotective agents- Kidney & Salivary gland
Patient concerns
FAQs
Is Natfost 500mg Injection FDA approved?
Yes, it is FDA an approved drug
What is Natfost 500mg Injection used for?
Natfost 500mg Injection is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer
How does Natfost 500mg Injection work?
It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Natfost 500mg Injection does not interfere with the action of cisplatin.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 50-51.
- Amifostine. Nijmegen, Netherlands: USB Pharma B.V.; 1999. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
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₹93.35
Inclusive of all taxes
1.0 Injection in 1 vial
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