Monolith 450mg Tablet SR
Prescription Required
Product introduction
Monolith 450mg Tablet SR is used in the treatment of bipolar disorder and mania in adults. It is sometimes used to treat other behavioral disorders as well. It reduces the frequency of manic episodes and decreases the intensity of those episodes that might occur.
Monolith 450mg Tablet SR is used to treat mood disorders.
Monolith 450mg Tablet SR is used to treat mood disorders.
Uses of Monolith Tablet SR
Benefits of Monolith Tablet SR
In Mania
Mania means extremely excited or elevated mood. Monolith 450mg Tablet SR helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Monolith 450mg Tablet SR will ensure that you have a better social life and are able to do daily activities more comfortably.
In Bipolar disorder
Monolith 450mg Tablet SR works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.
Side effects of Monolith Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Monolith
- Tremors
- Slurred speech
- Uncoordinated body movements
- Nausea
- Acne
- Increased white blood cell count
- Memory impairment
- Hair loss
- Goiter (enlarged thyroid gland)
- Skin rash
- Increased thirst
- Weight gain
- Polyuria
- Diarrhea
How to use Monolith Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Monolith 450mg Tablet SR is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Monolith 450mg Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Monolith 450mg Tablet SR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Monolith 450mg Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Monolith 450mg Tablet SR may cause side effects which could affect your ability to drive.
Monolith 450mg Tablet SR may make you feel sleepy, tired or dizzy. Monolith 450mg Tablet SR may also cause other effects that can make it dangerous to drive such as numbness, paralysis, weakness or fits (seizures).
Monolith 450mg Tablet SR may make you feel sleepy, tired or dizzy. Monolith 450mg Tablet SR may also cause other effects that can make it dangerous to drive such as numbness, paralysis, weakness or fits (seizures).
Kidney
CAUTION
Monolith 450mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Monolith 450mg Tablet SR may be needed. Please consult your doctor.
Use of Monolith 450mg Tablet SR is not recommended in patients with severe kidney disease.
Use of Monolith 450mg Tablet SR is not recommended in patients with severe kidney disease.
Liver
SAFE IF PRESCRIBED
Monolith 450mg Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Monolith 450mg Tablet SR may not be needed in these patients. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Monolith 450mg Tablet SR is one of the most effective long-term treatment for bipolar disorder.
- It may also be used for the treatment of mania.
- Your lithium blood levels, thyroid function, and kidney function may be monitored as long as you take this medicine.
- It may cause diarrhea and dehydration. Drink plenty of water and and use normal amounts of salt. Inform your doctor if you start or stop a low-salt diet.
- Monitor your weight during treatment as Monolith 450mg Tablet SR can cause weight gain.
- Do not drive or do anything that requires mental focus until you know how it affects you.
- Inform your doctor if you have persistent stomach upset, problems with your speech, or extreme drowsiness. Your dose may need to be adjusted.
- Do not take Monolith 450mg Tablet SR if you are pregnant or breastfeeding.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Organic Carbonic Acids
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Mood stabilizers
Patient concerns
FAQs
How quickly does Monolith 450mg Tablet SR work?
It takes some time before you see improvement in your symptoms after taking Monolith 450mg Tablet SR. Though it varies from person to person, it may take 1-3 weeks or longer for you to see the full benefits of Monolith 450mg Tablet SR. Do not stop taking Monolith 450mg Tablet SR if you feel you are not improving. Instead, discuss it with your doctor.
Does Monolith 450mg Tablet SR make you sleepy?
Yes, Monolith 450mg Tablet SR can cause nervous system disorders like sleepiness and dizziness and feeling confused. It can also cause rapid eye movements, blurred vision, or blind spots in your eyesight. If you experience any of these symptoms, consult your doctor. In addition, avoid driving or operating heavy machinery as it can be hazardous for you.
Is Monolith 450mg Tablet SR bad for kidneys?
Yes, Monolith 450mg Tablet SR may cause kidney problems. Monolith 450mg Tablet SR is not prescribed in patients who already have severe kidney impairment. The kidney problems may not be reversible and the symptoms include swollen ankles, passing a lot of urine and feeling thirsty. Before starting treatment with Monolith 450mg Tablet SR, your doctor will get blood tests done to see if your kidney function is normal. During Monolith 450mg Tablet SR therapy, any gradual or sudden changes in renal function, even within the normal range, may indicate the need for re-evaluation of treatment.
Can Monolith 450mg Tablet SR cause gain in weight?
Monolith 450mg Tablet SR can cause both weight gain or weight loss. You should keep a check on your weight during Monolith 450mg Tablet SR therapy. If you feel you are gaining or losing too much weight, consult your doctor who will assess whether the change in weight is due to Monolith 450mg Tablet SR or some other reason.
What is the most important information I should know about Monolith 450mg Tablet SR?
Monolith 450mg Tablet SR therapy should only be started if adequate facilities for assessing Monolith 450mg Tablet SR levels are available. This is because Monolith 450mg Tablet SR toxicity is related to increased levels of Monolith 450mg Tablet SR in blood. Monolith 450mg Tablet SR toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Monolith 450mg Tablet SR levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
How should Monolith 450mg Tablet SR be taken?
Take Monolith 450mg Tablet SR exactly as prescribed by your doctor. Check with your doctor if you are not sure. It is meant for oral administration and can be taken with or without food. However, if you start following a certain type of diet, talk to your doctor first. Any drastic changes in the amount of water you drink or amount of sodium (salt) in your diet may require more frequent monitoring of Monolith 450mg Tablet SR levels.
Which medicines decrease Monolith 450mg Tablet SR levels?
You should inform your doctor about the medicines you are taking before starting Monolith 450mg Tablet SR since many medicines interfere with the working of Monolith 450mg Tablet SR. Some medicines decrease the levels of Monolith 450mg Tablet SR in blood which means that it will not work well. These include theophylline (for asthma), caffeine, anything containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea used to treat skin conditions.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Lithium. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 349-54.
- Meltzer H. Antipsychotic Agents & Lithium. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 502-504.
- Drugs.com. Lithium Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lithium. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Marketer details
Name: Consern Pharma Limited
Address: Consern Pharma Private Limited, Kuljive Mahajan(Mg. Director), Rural Focal Point, V.P.O. Tibba, Ludhiana - 141120, Punjab, India
Country of origin: India
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