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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Introduction of Migrafen Tablet

Migrafen Tablet is a medicine used to prevent and treat migraine. It blocks the release of certain chemical messengers that cause pain and inflammation. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.

Migrafen Tablet is a combination of adenosine receptor (A1 & A2) antagonist, ergot derivative, analgesic & antipyretic-PCM, and dopamine (D2) receptor antagonist-prochlorperazine.

Uses of Migrafen Tablet

Benefits of Migrafen Tablet

In Migraine

Migrafen Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. It also contains caffeine that stimulates your brain to uplift your mood and give you a feeling of well being by improving your energy levels. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Migrafen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Migrafen

  • Sedation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Drowsiness
  • Urinary retention
  • Dryness in mouth
  • Increased heart rate
  • Constipation
  • Muscle pain

How to use Migrafen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Migrafen Tablet is to be taken with food.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Migrafen Tablet.
Pregnancy
UNSAFE
Migrafen Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Migrafen Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Occasional short-term use of Migrafen Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Driving
UNSAFE
Migrafen Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Migrafen Tablet should be used with caution in patients with kidney disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Migrafen Tablet should be used with caution in patients with liver disease. Dose adjustment of Migrafen Tablet may be needed. Please consult your doctor.

What if you forget to take Migrafen Tablet?

If you miss a dose of Migrafen Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Migrafen Tablet
₹12.0/Tablet
Vasograin Tablet
Cadila Pharmaceuticals Ltd
₹8.05/tablet
11% cheaper
NT Grain Tablet
Intas Pharmaceuticals Ltd
₹4.05/tablet
55% cheaper
₹2.8/tablet
69% cheaper
Migraneck Tablet
Leeford Healthcare Ltd
₹28.5/tablet
217% costlier
Livigrain Tablet
Lividus Pharmaceuticals Pvt Ltd
₹5/tablet
44% cheaper

Quick tips

Migrafen Tablet

  • Migrafen Tablet helps in the treatment and prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Migrafen Tablet affects you.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. 
  • Do not stop taking the medication suddenly as it can cause worsening of headaches.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

Patient concerns

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I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me
Dr. Pushkar Mani
Physician
it could be migraine
arrow

FAQs

Migrafen Tablet

What is Migrafen Tablet?

Migrafen Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.

What can cause or trigger a migraine attack?

Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.

Can I stop taking Migrafen Tablet when my migraine symptoms are relieved?

Migrafen Tablet is usually used for prevention and treatment of migraine attack. Migrafen Tablet should be continued as advised by the doctor.

Can the use of Migrafen Tablet cause constipation?

Yes, the use of Migrafen Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.

Can the use of Migrafen Tablet cause dry mouth?

Yes, the use of Migrafen Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Migrafen Tablet can increase the risk of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.

Does Migrafen Tablet expire?

Yes, Migrafen Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Migrafen Tablet after the expiry date.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Tulane University: School of Medicine. Caffeine. [Accessed 29 Jan. 2019] (online) Available from:External Link
  2. Drugs.com. Ergotamine. [Accessed 24 Apr. 2019] (online) Available from:External Link
  3. Prochlorperazine maleate. Skipton, UK: Dales Pharmaceuticals Limited; 2016. [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Leeford Healthcare Ltd
Address: Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116
Country of origin: India

MRP
120
Inclusive of all taxes
10.0 tablets in 1 strip
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