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Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Manoval 133.5mg/58mg Tablet

Prescription Required

Introduction of Manoval Tablet

Manoval 133.5mg/58mg Tablet is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves and hence, prevents seizures or fits.

Manoval 133.5mg/58mg Tablet is a combination of two sodium channel modulators (AED).

Uses of Manoval Tablet

Benefits of Manoval Tablet

In Epilepsy

Manoval 133.5mg/58mg Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of Manoval Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Manoval

  • Nausea
  • Vomiting
  • Weight gain
  • Loss of appetite
  • Gum swelling
  • Headache
  • Sleepiness
  • Tremors
  • Hair loss
  • Liver injury

How to use Manoval Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Manoval 133.5mg/58mg Tablet is to be taken with food.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Manoval 133.5mg/58mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Manoval 133.5mg/58mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Manoval 133.5mg/58mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Manoval 133.5mg/58mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Manoval 133.5mg/58mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Manoval 133.5mg/58mg Tablet may not be needed in these patients. Please consult your doctor.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Manoval 133.5mg/58mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Manoval 133.5mg/58mg Tablet may be needed. Please consult your doctor.
Use of Manoval 133.5mg/58mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Manoval Tablet?

If you miss a dose of Manoval 133.5mg/58mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Manoval 133.5mg/58mg Tablet
₹1.99/Tablet
Valporate Chrono 200 Tablet
Crescent Therapeutics Ltd
₹5.45/tablet
174% costlier
Valate Chrono 200 Tablet
Psychotropics India Ltd
₹2.7/tablet
36% costlier
Cinaval Chrono 200 Tablet
USV Ltd
₹3.51/tablet
76% costlier
Navalin Chrono 200 Tablet
Molekule India Pvt Ltd
₹4.24/tablet
113% costlier
Migrid Crono 200 Tablet
Scott Edil Pharmacia Ltd
₹4.5/tablet
126% costlier

Quick tips

Manoval Tablet

  • You have been prescribed Manoval 133.5mg/58mg Tablet for treatment and prevention of seizures.
  • Take it at the same time every day to maintain consistent levels in your body.
  • Do not drive or do anything that requires mental focus until you know how Manoval 133.5mg/58mg Tablet affects you.
  • Avoid consuming alcohol when taking Manoval 133.5mg/58mg Tablet, as it may cause excessive sleepiness or drowsiness.
  • Monitor your weight during the treatment as Manoval 133.5mg/58mg Tablet can cause weight gain.
  • Your doctor may monitor Manoval 133.5mg/58mg Tablet level, blood counts and liver function regularly throughout your treatment.  Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.
  • Do not take Manoval 133.5mg/58mg Tablet if you are pregnant or planning to conceive or breastfeeding.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

Patient concerns

arrow
3-4 attack of strokes in 3 yrs nothing found in CT scan & EEG.these tests are done again after 3 months. But nothing found. Doctors prescribed me Oxetol 450 mg.doctor say course of medicine is 2-3 yrs.I drink and smoke addicted to drug I don't understand if the test show nothing then why strokes happens to me?
Dr. Vikas Sharma
Neurology
is it stroke or epilepsy; as u are on medicine for epilepsy
MORE
Sir i use in tablets phenytion Last two months i use this tablets
Dr. Jyoti Kapoor Madan
Psychiatry
It's treatment for epilepsy.
MORE
arrow

FAQs

Manoval Tablet

Can the use of Manoval 133.5mg/58mg Tablet cause sleepiness or drowsiness?

Yes, Manoval 133.5mg/58mg Tablet may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.

Can I drink alcohol while taking Manoval 133.5mg/58mg Tablet?

No, avoid drinking alcohol while taking Manoval 133.5mg/58mg Tablet. Drinking alcohol will increase the side effects caused by Manoval 133.5mg/58mg Tablet.

Can Manoval 133.5mg/58mg Tablet be stopped when epilepsy symptoms are relieved?

No, Manoval 133.5mg/58mg Tablet should be continued as advised by the doctor. Stopping Manoval 133.5mg/58mg Tablet suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Manoval 133.5mg/58mg Tablet, consult the doctor for re-evaluation.

Will a higher than the recommended dose of Manoval 133.5mg/58mg Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.

What are the instructions for the storage and disposal of Manoval 133.5mg/58mg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Linde M, Mulleners WM, Chronicle EP, et al. Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. Cochrane Database Syst Rev. 2013;(6):CD010611. [Accessed 23 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Sodium Valporate. [Accessed 23 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Valporic acid. [Accessed 23 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Mano Pharma Pvt Ltd
Address: no. 447, poonamallee high road, aminjikarai, chennai 600029
Country of origin: India
MRP
₹19.9
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT
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