Manocept 250mg Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It works by suppressing your body’s immune system so that it does not attack the new organ.

It is an immunosuppresant.

Uses of Manocept Tablet

Prevention of organ rejection in transplant patients

Benefits of Manocept Tablet

In Prevention of organ rejection in transplant patients

Manocept 250mg Tablet belongs to a group of medicines known as immunosuppressive agents. It lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ.

Side effects of Manocept Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Manocept

Nausea
Vomiting
Diarrhea
Abdominal pain
Headache
High blood pressure
Decreased white blood cell count (neutrophils)
Fungal infection
Low blood platelets
Anemia (low number of red blood cells)
Skin cancer
Bacterial infection
Hypercholesterolemia (high cholesterol)
Viral infection
Electrolyte imbalance
Gout
Weight loss
Tremors
Convulsion
Tumor

How to use Manocept Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Manocept 250mg Tablet is to be taken with food.

How Manocept Tablet works

Manocept 250mg Tablet is an immunosuppressant. It reduces the action of the body's own defense system (the immune system) and prevents rejection of the transplanted organ.

Safety advice

Alcohol

SAFE

Consuming alcohol with Manocept 250mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Manocept 250mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Manocept 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Manocept 250mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Manocept 250mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Manocept 250mg Tablet may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Manocept 250mg Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Manocept 250mg Tablet

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Quick tips

Your doctor has prescribed Manocept 250mg Tablet to stop your body from rejecting a transplanted organ (e.g. kidney, heart or liver).
It may take 6 to 12 weeks for Manocept 250mg Tablet to start working. Keep taking it as prescribed.
It may cause birth defects so birth control is required in females with reproductive potential.
It makes you more susceptible to getting infections. Avoid contact with people who have an infection. Consult your doctor immediately if you develop a sore throat, high temperature, any other signs of infections.
Protect yourself from direct sunlight by wearing protective clothing and applying a sunscreen with a high sun protection factor (SPF).
Take it with food to minimize possible side effects like nausea and stomach pain.
Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood. Inform your doctor if you experience symptoms such as unexplained bruising or bleeding, sore throat, mouth ulcers, or fever.

Fact Box

Chemical Class

Phthalide Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- Purine analogs

Patient concerns

Nephrologist considered for consulting Function of kidney transplant patients suffering from tuberculosis

Dr. Praveen Pushkar

Urology

Get kidney function test done

Difficulty in excretory, and rejection of stool.

Dr. Aanchal Maheshwari

Ayurveda

take triphala churan 1 spoon at night wioth abhyarishtam 20 ml mixed with water

Dear respected sir/madam, my uncle is suffering from alcoholic liver cirrhosis and ascites due to prolonng drinking. Water is accumulated around the belly. Less ddesire to eat anything. Doctor is saying for liver transplant. Could please suggest the best treatment available in allopathy to treat this problem. Thank you very very much.

Dr. Pushkar Mani

Physician

liver transplant only, consult in ILBS delhi

Prevention of acene and pimples

Dr. Manju Singh

Homeopathy

Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.

FAQs

Can Manocept 250mg Tablet cause cancer?

Manocept 250mg Tablet may increase your chances of certain cancers like skin cancer and lymphoma (cancer of the lymph system). When outside, avoid unnecessary or prolonged exposure to sunlight, wear protective clothing, and apply sunscreen. Call your doctor if you experience a new skin sore or bump, a change in the size or color of a mole, a brown or black skin lesion (sore) with uneven edges or a sore whose one part does not look like the other, skin changes, sores that do not heal. Also, inform the doctor if you experience unexplained fever, tiredness that does not go away, weight loss, or pain or swelling in the neck, groin, or armpits.

Why has my doctor given me Manocept 250mg Tablet after I have had a kidney transplant?

Manocept 250mg Tablet is an immunosuppressant. Manocept 250mg Tablet has been prescribed to you to help your body accept the donor's kidney. It does so by working on the cells of your immune system, which fight with any foreign substance and reject its presence. This helps in making the transplanted organ more acceptable to your body.

Is Manocept 250mg Tablet a steroid or chemotherapy medicine? Can it cause hair loss?

Manocept 250mg Tablet is neither a steroid nor a chemotherapy medicine. It is an immunosuppressant which means that it acts on your immune system to suppress or weaken it so that your body does not reject the donated organ of another person. Hair loss is a common side effect of Manocept 250mg Tablet.

Do I need any special tests while taking Manocept 250mg Tablet?

Since Manocept 250mg Tablet can affect blood count and affect the kidneys and liver, your doctor will ask you to have a blood test before you start the treatment. Once the treatment starts, your doctor will suggest you take regular blood tests to check for any changes in the blood. These blood tests will help monitor your response to the medicine and the development of any side effects.

My doctor has asked me to stay away from a person who has chickenpox or shingles. Why?

Manocept 250mg Tablet is an immunosuppressant, which means that it decreases the activity of the immune system. Since your immune system is already weak, if you come in contact with a patient of chickenpox or shingles, you may develop it too. This is the reason that your doctor has advised you to be cautious. Therefore, follow your doctor’s advice and contact your doctor immediately if you get chickenpox or shingles as you may require special treatment.

What precautions should a female follow while taking Manocept 250mg Tablet?

Do not take Manocept 250mg Tablet if you are pregnant or are planning a pregnancy. There is a high risk of miscarriage (loss of the pregnancy) during the first 3 months of pregnancy. It may even cause birth defects (problems that are present at birth) in the newborn. Therefore, it is advised that you should use two acceptable forms of birth control together for 4 weeks before you start taking Manocept 250mg Tablet, during the treatment, and for 6 weeks after you stop taking Manocept 250mg Tablet. It is important to use a second form of birth control along with birth control pills as Manocept 250mg Tablet may decrease the effectiveness of birth control pills. Your doctor will suggest the two birth control methods that\ suit you the best.

What precautions should a male follow while taking Manocept 250mg Tablet?

It is recommended that either the man or her partner should use reliable contraception during treatment and for 90 days after the treatment. Men should not donate semen during the therapy or for 90 days following discontinuation of Manocept 250mg Tablet.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1014-15.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 973.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 943-45.
Mycophenolate mofetil. Barnstaple, Devon: Accord-UK Ltd.; 2009 [revised 10 Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
Mycophenolate mofetil. South San Francisco, California: Genentech USA, Inc.; 1995 [revised Feb. 2019]. [Accessed 17 Jun. 2019] (online) Available from:
Mycophenolate mofetil. Grenzach-Wyhlen, Germany: Roche Pharma AG; 2018. [Accessed 17 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation. Mycophenolate mofetil. [Accessed 25 Jul. 2023] (online) Available from:
Ensley RD, Bristow MR, Olsen SL, et al. The use of mycophenolate mofetil (RS-61443) in human heart transplant recipients. Transplantation. 1993 Jul;56(1):75-82. [Accessed 01 Aug. 2023] (online) Available from:
Mycophenolate mofetil. Basel, Switzerland: F. Hoffmann-La Roche Ltd.; 2021. [Accessed 25 Jul. 2023] (online) Available from:
Cell Cept. Mycophenolate mofetil. [Accessed 25 Jul. 2023] (online) Available from:
Mycophenolate mofetil [Prescribing Information]. Ahmedabad, India: Intas Pharmaceuticals Limited; 2023. [Accessed 25 Jul. 2023] (online) Available from:

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Country of origin: India

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