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Last updated
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Letogen 5mg Tablet SR


Product introduction

Letogen 5mg Tablet SR helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.

Letogen 5mg Tablet SR is used to treat breast cancer in women who have gone through the menopause.

Uses of Letogen Tablet SR

Benefits of Letogen Tablet SR

In Treatment of Breast cancer

Letogen 5mg Tablet SR relieves the symptoms of breast cancer such as breast lumps, bloody discharge from the nipple, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

In Treatment of Infertility due to anovulation

Letogen 5mg Tablet SR helps in the normal development of an egg in a woman's ovary (female reproductive organ) and stimulates the release of the egg during a process called ovulation. This helps to treat infertility in women. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective.

Side effects of Letogen Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Letogen

  • Fatigue
  • Hypercholesterolemia (high cholesterol)
  • Increased sweating
  • Hot flashes
  • Bone pain
  • Dizziness
  • Joint pain
  • Edema (swelling)
  • Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Letogen Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Letogen 5mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
SAFE
Consuming alcohol with Letogen 5mg Tablet SR does not cause any harmful side effects.
Pregnancy
UNSAFE
Letogen 5mg Tablet SR is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Letogen 5mg Tablet SR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Letogen 5mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Letogen 5mg Tablet SR is safe to use in patients with kidney disease. No dose adjustment of Letogen 5mg Tablet SR is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Letogen 5mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Letogen 5mg Tablet SR may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Letogen 5mg Tablet SR
₹59.8/Tablet SR
₹38.6/tablet sr
35% cheaper
₹71.8/tablet sr
20% costlier

Quick tips

  • You have been prescribed Letogen 5mg Tablet SR for the treatment of breast cancer or infertility due to anovulation.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Letogen 5mg Tablet SR affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Letogen 5mg Tablet SR can alter their levels.
  • Do not take Letogen 5mg Tablet SR if you are pregnant or breastfeeding 

Fact Box

Chemical Class
Diphenylmethane Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Aromatase inhibitor

Patient concerns

arrow
Breast pain not able to sleep already take test no cancer but pain
Dr. Megha Gupta
Obstetrics and Gynaecology
Hi Rajeshwari. Breast pain can be due to hormonal changes as well. Please visit a gynaecologist in your area for a thorough evaluation.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
arrow

FAQs

Q. Why have I been prescribed Letogen 5mg Tablet SR?

Letogen 5mg Tablet SR is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

Q. How does Letogen 5mg Tablet SR work?

Letogen 5mg Tablet SR is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.

Q. For how long should I take Letogen 5mg Tablet SR?

If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letogen 5mg Tablet SR till the tumor shows progression. In cases where Letogen 5mg Tablet SR is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letogen 5mg Tablet SR followed by 3 years of tamoxifen.

Q. If I am taking irbesartan to control my blood pressure, can I take Letogen 5mg Tablet SR?

Yes, you can take irbesartan and Letogen 5mg Tablet SR together. However, be careful and keep a regular check on your blood pressure since Letogen 5mg Tablet SR may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Q. Does Letogen 5mg Tablet SR affect vision?

Although it is very uncommon, Letogen 5mg Tablet SR may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

Q. My friend who is taking Letogen 5mg Tablet SR often sweats a lot. Is it because of Letogen 5mg Tablet SR?

This could be a sign of hot flushes which is a very common side effect of Letogen 5mg Tablet SR. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letogen 5mg Tablet SR. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

Q. What are the serious side effects of Letogen 5mg Tablet SR?

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letogen 5mg Tablet SR include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
  2. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
  4. Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link
  6. National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:External Link
  7. Letrozole [Package Insert]. Mumbai, India: HOPE Lifecare. [Accessed 08 Jul. 2023]. (online) Available from:External Link
  8. Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Amagen India Life Sciences
Address: House No. 24 Pocket B-4 Sector 8 Rohini, Rohini Sector 8, Jammu-110085, Jammu & Kashmir, India
Country of origin: India

MRP
299
Inclusive of all taxes
5.0 tablet sr in 1 strip
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