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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Lethyrox 12.5 Tablet

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Product introduction

Lethyrox 12.5 Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which is not being produced by your thyroid gland in sufficient quantity and helps regulate your body’s energy and metabolism.

Lethyrox 12.5 Tablet is used to treat deficiency of chemical controlling growth and energy production

Uses of Lethyrox Tablet

Benefits of Lethyrox Tablet

In Treatment of Hypothyroidism

Lethyrox 12.5 Tablet is a synthetic version of thyroxine, a hormone that is naturally produced in your body. When your body does not produce enough thyroxine, you get hypothyroidism. Some symptoms of hypothyroidism include tiredness, weight gain, and muscle aches. This medicine raises your hormone level to the right amount and helps you get rid of these symptoms. For most people, this is a lifelong medication and should not be discontinued without talking to your doctor.

It may take a while for this medicine to work properly. Your doctor may get regular blood tests done to determine the effectiveness of this medicine and to make sure that you are on the right dose.

Side effects of Lethyrox Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lethyrox

  • Palpitations
  • Vomiting
  • Anxiety
  • Diarrhea
  • Weight loss
  • Nervousness
  • Increased appetite
  • Tremors

How to use Lethyrox Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lethyrox 12.5 Tablet is to be taken empty stomach.

How Lethyrox Tablet works

Lethyrox 12.5 Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).

Safety advice

Alcohol
SAFE
Consuming alcohol with Lethyrox 12.5 Tablet does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Lethyrox 12.5 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Lethyrox 12.5 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Lethyrox 12.5 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Lethyrox 12.5 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Lethyrox 12.5 Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Lethyrox 12.5 Tablet
₹1.09/Tablet
Thyrox 12.5 Tablet
Macleods Pharmaceuticals Pvt Ltd
₹1.51/tablet
39% costlier
₹1.51/tablet
39% costlier
₹1.44/tablet
32% costlier
Thyrorich 12.5mcg Tablet
Primus Pharmaceuticals
₹1.12/tablet
3% costlier
Thyrobronz 12.5 Tablet
Scudder Life Sciences Private Limited
₹1.53/tablet
41% costlier

Quick tips

  • Lethyrox 12.5 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
  • It may take 6 to 8 weeks to get the full effect.
  • For most people, Lethyrox 12.5 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
  • Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
  • Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
  • Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
  • Inform your doctor before changing the brand of Lethyrox 12.5 Tablet as all brands may not have the same effect.

Fact Box

Chemical Class
Iodinated amino acid derivative
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Thyroid hormones

Patient concerns

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I have affect by hypothyroidism if there any problem to get pregnant
Dr. Satyam S. Bhavsar
Physician
yes, hypothyroidism may effect fertility.
Please check attached report for thyroid and other problems. Her weight is around 88 kg and height is 5 feet 1 inch.
Dr. Shubhra Chandhan Pradhan
ENT
You have subclinical hypothyroidism. Consult an endocrinologist
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User feedback


FAQs

What should I do if I accidentally take more than the dose required?

An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.

How long do I need to take Lethyrox 12.5 Tablet?

You should take Lethyrox 12.5 Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.

How should Lethyrox 12.5 Tablet be taken?

Take Lethyrox 12.5 Tablet exactly as advised by your doctor. Lethyrox 12.5 Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.

Being a diabetic what should I be aware of while taking Lethyrox 12.5 Tablet?

Lethyrox 12.5 Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.

What does thyroxine do? Why is it important?

Thyroxine hormone controls how much energy your body uses. It plays an important role in regulating your body weight, muscle strength, body temperature, and even your mood. Along with that, it is important for your digestion, heart muscles, brain development, and bone health.

Does Lethyrox 12.5 Tablet affect contraception?

Oral birth control pills, which contain both estrogen and progesterone may reduce the amount of Lethyrox 12.5 Tablet in your body and therefore the dose of Lethyrox 12.5 Tablet may have to be increased.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Brent GA, Koenig RJ. Thyroid and Anti-Thyroid Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1142-43.
  2. Dong BJ, Greenspan FS. Thyroid & Antithyroid Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 674-75.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 796-98.
  4. Levothyroxine sodium. East Sussex, UK: Custom Pharmaceuticals Ltd.; 2018. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Levothyroxine. Bohemia, New York: Jerome Stevens Pharmaceuticals, Inc. [Accessed 04 Apr. 2019] (online) Available from:External Link
  6. Levothyroxine [Prescribing Information]. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

MRP
54.64
Inclusive of all taxes
50.0 tablets in 1 bottle
SOLD OUT

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