Author Details
Written By
BDS
Reviewed By
DM, MD
Last updated
05 Dec 2023 | 06:14 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Larentine 5 Tablet


Product introduction

Larentine 5 Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.

Larentine 5 Tablet is used for the treatment of moderate to severe Alzheimer's disease (disease of memory loss)

Uses of Larentine Tablet

  • Alzheimer's disease

Benefits of Larentine Tablet

In Alzheimer's disease

Larentine 5 Tablet improves learning, memory and information processing (cognitive function) in people with moderate to severe Alzheimer's disease. These problems in memory and thinking may start interfering with daily activities and worsen your condition. This medicine will help in managing Alzheimer’s disease effectively. It will make it easier for you to carry out your daily activities and improve your quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.

Side effects of Larentine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Larentine

  • Dizziness
  • Headache
  • Confusion
  • Constipation

How to use Larentine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larentine 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Larentine Tablet works

Larentine 5 Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Larentine 5 Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate.  involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Larentine 5 Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Larentine 5 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Larentine 5 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Larentine 5 Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Larentine 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Larentine 5 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Larentine 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Larentine 5 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Larentine 5 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Larentine Tablet?

If you miss a dose of Larentine 5 Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Larentine 5 Tablet
₹8.8/Tablet
Admenta 5 Tablet
Sun Pharmaceutical Industries Ltd
₹5.7/tablet
35% cheaper
Nemdaa 5 Tablet
Intas Pharmaceuticals Ltd
₹8.95/tablet
2% costlier
Almantin 5mg Tablet
Sun Pharmaceutical Industries Ltd
₹2.4/tablet
73% cheaper
Mentra 5mg Tablet
Zydus Cadila
₹4.8/tablet
45% cheaper
Mentadem 5mg Tablet
Torrent Pharmaceuticals Ltd
₹4.92/tablet
44% cheaper

Quick tips

  • You have been prescribed Larentine 5 Tablet to treat dementia (memory loss) in patients with Alzheimer's disease.
  • It is well tolerated and has lesser side effects as compared to other similar medicines.
  • Be cautious while driving or doing anything that requires concentration until you know how Larentine 5 Tablet affects you.
  • Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Chemical Class
Amantadine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
NMDA inhibitors- Alzheimer's disease

Patient concerns

arrow
Why the failure of Alzheimer's therapy now a days???
Dr. Vikas Sharma
Neurology
as the disese mechanisms are still not defined in absolute terms; still PATIENT is needed and is ongoing
Sir, My father ( an advocate) has developed symptoms of Alzheimer recently and sometimes he takes medicines on his own. He gets weak and unable to walk after taking tablets. Is there any test which can tell which medicines that he took? He takes Ayurved, Allopath, Homeopathy all and does not listen to me. Kindly help
Dr. Ila Jain Khandelwal
Pathology
Dear Sir Thank you for consulting with me. Alzheimer's disease is a difficult disease to handle since patient develops dementia or forgetfulness. There are no blood tests which can tell you which medicines he took. Please consult a neurologist/ Psychiatrist
arrow

User feedback


FAQs

Does Larentine 5 Tablet have abuse potential?

No, Larentine 5 Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.

When and how Larentine 5 Tablet should be taken?

Larentine 5 Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.

How long does it take for Larentine 5 Tablet to start working?

For Larentine 5 Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.

What are the symptoms of overdosage of Larentine 5 Tablet?

The symptoms which can be observed due to an overdose of Larentine 5 Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.

How does Larentine 5 Tablet affect a person with dementia?

Larentine 5 Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Larentine 5 Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.

What is dementia?

Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.

Can I just stop taking Larentine 5 Tablet?

No, Larentine 5 Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.

Does Larentine 5 Tablet make you sleepy?

Yes, Larentine 5 Tablet may make you sleepy. Larentine 5 Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.

Can Larentine 5 Tablet be combined with donepezil?

Yes, Larentine 5 Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.

What medicines should I avoid while taking Larentine 5 Tablet?

Larentine 5 Tablet can interact with several medicines. Taking other medicines along with Larentine 5 Tablet can either make Larentine 5 Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.

Does Larentine 5 Tablet have any interaction with cardiac medicines?

Yes, Larentine 5 Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Larentine 5 Tablet which may cause increased toxicity.

Can I stop taking Larentine 5 Tablet if I feel better?

No, keep using Larentine 5 Tablet as advised by your doctor, even if you feel well. Stopping Larentine 5 Tablet can bring back your symptoms of dementia.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
  3. Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
  4. Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015]. [Accessed 25 Mar 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation. Memantine. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  8. Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  9. Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023. [Accessed 11 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: La Renon Healthcare Pvt Ltd
Address: Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Country of origin: India

MRP
88
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.