Kombiglyze XR 5mg/500mg Tablet
Prescription Required
Introduction of Kombiglyze Tablet XR
Kombiglyze XR 5mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.
Kombiglyze XR 5mg/500mg Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.
Kombiglyze XR 5mg/500mg Tablet is a medicine used in the treatment of type 2 diabetes mellitus. It provides better control of blood sugar when single therapy is not effective and reduces both fasting and postmeal sugar levels. It should be used along with a proper diet and exercise for maximum effect. Monitor your blood sugar level regularly while you are taking this medicine as it may cause hypoglycemia (low blood sugar level) as a side effect.
Uses of Kombiglyze Tablet XR
Benefits of Kombiglyze Tablet XR
In Treatment of Type 2 diabetes mellitus
Kombiglyze XR 5mg/500mg Tablet is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.
Side effects of Kombiglyze Tablet XR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Kombiglyze
- Hypoglycemia (low blood glucose level)
- Nausea
- Vomiting
- Diarrhea
- Decreased appetite
- Urinary tract infection
How to use Kombiglyze Tablet XR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kombiglyze XR 5mg/500mg Tablet is to be taken with food.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Kombiglyze XR 5mg/500mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Kombiglyze XR 5mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Kombiglyze XR 5mg/500mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
UNSAFE
Kombiglyze XR 5mg/500mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
UNSAFE
Kombiglyze XR 5mg/500mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Kombiglyze Tablet XR?
If you miss a dose of Kombiglyze XR 5mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Kombiglyze Tablet XR
- Take it with food to lower your chance of having an upset stomach.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Kombiglyze XR 5mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
Patient concerns
User feedback
Patients taking Kombiglyze XR 5mg/500mg Tablet
Once A Day
93%
Twice A Day
5%
Thrice A week
1%
What are you using Kombiglyze Tablet XR for?
Type 2 diabet*
92%
Others
8%
*Type 2 diabetes
How much was the improvement?
Excellent
80%
Average
20%
What were the side-effects while using Kombiglyze XR 5mg/500mg Tablet?
Headache
50%
Bowel disturb*
25%
No Side Effec*
25%
*Bowel disturbance, No Side Effect
How do you take Kombiglyze Tablet XR?
Empty stomach
50%
With food
50%
Please rate Kombiglyze XR 5mg/500mg Tablet on price
Expensive
67%
Not Expensive
25%
Average
8%
FAQs
Kombiglyze Tablet XR
What should I tell my doctor before taking Kombiglyze XR 5mg/500mg Tablet?
Before taking Kombiglyze XR 5mg/500mg Tablet, inform your doctor if you have any problems with your kidneys, liver, bladder, heart or pancreas. Tell your doctor if you ever had or have any risk factors for ketoacidosis (such as type 1 diabetes, changes in diet, reduced appetite or if you are going to have a surgery). Let your doctor know about all the other medicines or supplements you are taking because they may affect, or be affected by, this medicine. Consult your doctor before taking Kombiglyze XR 5mg/500mg Tablet if you are planning to conceive, if you are pregnant or breastfeeding to avoid any harmful effects on the baby.
Who should not take Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet is not recommended for people who are allergic to it, have severe kidney problems or are on dialysis. Additionally, avoid taking Kombiglyze XR 5mg/500mg Tablet if you are trying to get pregnant, already pregnant or breastfeeding to avoid any harmful effects on the baby.
Does Kombiglyze XR 5mg/500mg Tablet cause weight gain?
No, Kombiglyze XR 5mg/500mg Tablet is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Kombiglyze XR 5mg/500mg Tablet.
Is Kombiglyze XR 5mg/500mg Tablet bad for your kidneys?
No, Kombiglyze XR 5mg/500mg Tablet is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. Conditions like kidney problems may require dose modification.
Do I still have to manage my diet and exercise while on Kombiglyze XR 5mg/500mg Tablet?
Yes, it is important to manage your diet and exercise while taking Kombiglyze XR 5mg/500mg Tablet. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.
Can my blood sugar levels go too low on Kombiglyze XR 5mg/500mg Tablet?
Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Kombiglyze XR 5mg/500mg Tablet. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Kombiglyze XR 5mg/500mg Tablet. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.
What is the most important information I should know about Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Kombiglyze XR 5mg/500mg Tablet may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Kombiglyze XR 5mg/500mg Tablet can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Kombiglyze XR 5mg/500mg Tablet. In addition to that, problems related to kidneys should also be discussed with the doctor.
What will happen if I accidentally take more than the prescribed dose of Kombiglyze XR 5mg/500mg Tablet?
If you have accidentally taken more than the prescribed dose of Kombiglyze XR 5mg/500mg Tablet, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.
How long do I need to take Kombiglyze XR 5mg/500mg Tablet?
Kombiglyze XR 5mg/500mg Tablet only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Kombiglyze XR 5mg/500mg Tablet as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.
What if I miss a dose of Kombiglyze XR 5mg/500mg Tablet?
If you miss a dose and it is less than 12 hours since the time of your dose, take it as soon as you remember it. However, if it is more than 12 hours since your missed dose, take Kombiglyze XR 5mg/500mg Tablet as per the regular schedule and skip the missed dose. Do not take a double dose to make up for the forgotten dose as it increases the risk of developing side effects.
Is Kombiglyze XR 5mg/500mg Tablet safe to be taken for a long term?
Yes, it is safe to take Kombiglyze XR 5mg/500mg Tablet for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Kombiglyze XR 5mg/500mg Tablet as long as your doctor recommends it. Remember, Kombiglyze XR 5mg/500mg Tablet only helps to keep your blood sugar levels under control but does not cure your diabetes.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Saxagliptin and metformin hydrochloride extended release. Wilmington, Delaware: AstraZeneca Pharmaceuticals LP; 2017. [Accessed 22 Jan. 2019] (online) Available from:
- Saxagliptin/metformin. Macclesfield, Cheshire: AstraZeneca UK Limited; 2017. [Accessed 28 Jan. 2019] (online) Available from:
- Metformin hydrochloride + saxagliptin hydrochloride. Sweden: AstraZeneca AB; 2011 [revised 13 Aug. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
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Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: United states
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