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PhD (Pharmacology), PGDPRA
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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Isentress 400mg Tablet


Product introduction

Isentress 400mg Tablet is an antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It prevents the multiplication of viruses in human cells and clears up your infection.

Isentress 400mg Tablet is used to control and treat HIV (viral) infection that causes AIDS

Uses of Isentress Tablet

Benefits of Isentress Tablet

In HIV infection

Isentress 400mg Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Isentress Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Isentress

  • Diarrhea
  • Dizziness
  • Fatigue
  • Headache
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Abdominal pain
  • Abnormal dreams
  • Decreased appetite
  • Depression
  • Flatulence
  • Nightmares
  • Vomiting
  • Weakness

How to use Isentress Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isentress 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Isentress 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Isentress 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Isentress 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Isentress 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Isentress 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isentress 400mg Tablet is recommended.
Liver
CAUTION
Isentress 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Isentress 400mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Isentress 400mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Isentress 400mg Tablet
₹144.82/Tablet
₹146.21/tablet
1% costlier
Raltegravir 400mg Tablet
Globela Pharma Pvt Ltd
₹144.82/tablet
same price

Quick tips

  • Take it with or without food, preferably at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Do not take antacids or calcium supplements an hour before or two hours after taking Isentress 400mg Tablet.
  • Your doctor may get regular blood tests done to monitor your blood cell counts and liver function during treatment with this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Pyrrolidinone derivative
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Integrase (HIV) inhibitors

Patient concerns

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hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero
Dr. Atula Gupta
Dermatology
You still need to be on ART even if the viral load is undetectable
i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner
arrow

User feedback


FAQs

Is raltegravir a protease inhibitor?

No. Raltegravir is an anti HIV drug. It does not have any known inhibitory effect on enzyme protease

What is Isentress 400mg Tablet used for?

Isentress 400mg Tablet is used for the treatment for human immunodeficiency virus (HIV) infection

How does Isentress 400mg Tablet work?

How does Isentress 400mg Tablet inhibit HIV viral replication?Isentress 400mg Tablet works by inhibiting the action of an enzyme called integrase which is essential for the multiplication and survival of the virus (viral replication), thereby reducing HIV causing virus in the body.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1658-659.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 866-67.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1192-194.
  4. Raltegravir potassium. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2007 [revised 18 Oct. 2018]. [Accessed 28 Jan 2019] (online) Available from:External Link
  5. Raltegravir. Whitehouse Station, New Jersey: MERCK & CO., Inc.; 2007 [revised Jul. 2009]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:External Link

Marketer details

Name: MSD Pharmaceuticals Pvt Ltd
Address: Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,
Country of origin: India

MRP
8689
Inclusive of all taxes
60.0 tablets in 1 bottle
SOLD OUT

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