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Author Details
Written By
Dr. Anuj Saini 2
MMST, MBBS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Guncef 50mg Tablet

Prescription Required

Product introduction

Guncef 50mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Guncef 50mg Tablet is used in treating prostate cancer that require certain male body chemicals to grow

Uses of Guncef Tablet

Benefits of Guncef Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Guncef 50mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Guncef Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Guncef

  • Anemia (low number of red blood cells)
  • Rash
  • Abdominal pain
  • Breast enlargement in male
  • Breast tenderness
  • Constipation
  • Decreased appetite
  • Decreased libido
  • Depression
  • Dizziness
  • Indigestion
  • Flatulence
  • Hot flashes
  • Increased liver enzymes
  • Nausea
  • Sleepiness
  • Weakness
  • Weight gain

How to use Guncef Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Guncef 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Guncef 50mg Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Guncef 50mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Guncef 50mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Guncef 50mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Guncef 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Guncef 50mg Tablet is recommended.
Liver
CAUTION
Guncef 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Guncef 50mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable while you are taking this medicine.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Guncef 50mg Tablet
₹44.0/Tablet
Calutide 50 Tablet
Cipla Ltd
₹52.26/tablet
19% costlier
Caluran 50 CP Tablet
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₹18.6/tablet
58% cheaper
Tabi Tablet
Dr Reddy's Laboratories Ltd
₹43.04/tablet
2% cheaper
Caluran 50 Tablet
Sun Pharmaceutical Industries Ltd
₹29.5/tablet
33% cheaper
Utamide Tablet
Intas Pharmaceuticals Ltd
₹41.26/tablet
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Quick tips

  • You have been prescribed Guncef 50mg Tablet for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Guncef 50mg Tablet.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class
Trifluoromethylbenzenes Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Androgen receptor antagonist

Patient concerns

arrow
Sir ,In my penis inside black dark spot is coming plz suggest me for better medicine Thank
Dr. Vinod Raina
Sexology
Take tab guncef 500mg bd for five days
MORE
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
MORE
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FAQs

Can Guncef 50mg Tablet cause infertility?

There is limited data to support that Guncef 50mg Tablet causes infertility. Guncef 50mg Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).

What should I avoid while taking Guncef 50mg Tablet?

Skin sensitivity has been observed in some patients while taking Guncef 50mg Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Guncef 50mg Tablet.

Is Guncef 50mg Tablet a form of chemotherapy?

No, Guncef 50mg Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Guncef 50mg Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.

Does Guncef 50mg Tablet cause hair loss?

Yes, Guncef 50mg Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.

What is Guncef 50mg Tablet prescribed for?

Guncef 50mg Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Guncef 50mg Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.

When should I take Guncef 50mg Tablet?

Guncef 50mg Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.

Can Guncef 50mg Tablet cause diarrhea?

Yes, Guncef 50mg Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.

How long do I need to take Guncef 50mg Tablet?

Guncef 50mg Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.
Related lab tests
  • Prostate Specific Antigen (Free) PSA
  • Prostate Specific Antigen (Total) PSA

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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1766.
    2. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
    3. Bicalutamide. Sellersville, PA: TEVA Pharmaceutical; 1995 [revised Jun. 2009]. [Accessed 26 Mar. 2019] (online) Available from:External Link
    4. Bicalutamide. Capability Green: AstraZeneca UK; 2000 [revised 08 Feb. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
    5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

    Marketer details

    Name: Oster Remedies
    Address: 1882, Basement Floor, Near Jagram Mandir,Kotla Mubarakpur,South Ext. Part -1,New Delhi - 110003
    Country of origin: India
    MRP
    ₹440
    Inclusive of all taxes
    10.0 tablets in 1 strip
    SOLD OUT
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