Grafishield 0.5 Capsule
Prescription Required
Product introduction
Grafishield 0.5 Capsule is used along with other medicines to prevent your body from rejecting a new organ (e.g., liver, kidney, or heart) after transplant. It does so by weakening your body’s immune system, so it does not attack the new organ. This medication belongs to a class of drugs known as immunosuppressants.
Grafishield 0.5 Capsule is used to prevent the body rejecting the organ that is transplanted
Grafishield 0.5 Capsule is used to prevent the body rejecting the organ that is transplanted
Uses of Grafishield Capsule
Benefits of Grafishield Capsule
In Prevention of organ rejection in transplant patients
Grafishield 0.5 Capsule belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine weakens your immune response (which usually fights infection) and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful. You should continue taking the medicine and should not stop it until your doctor says so.
Side effects of Grafishield Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Grafishield
- Increased glucose level in blood
- Kidney damage
- Insomnia (difficulty in sleeping)
- Tremors
- High blood pressure
- Infection
How to use Grafishield Capsule
Take this medicine in the dose and duration as advised by your doctor. Grafishield 0.5 Capsule is to be taken empty stomach.
How Grafishield Capsule works
Grafishield 0.5 Capsule is an immunosuppressant. It works by suppressing your body’s immune response following the transplant of an organ (e.g., liver, kidney, heart). This helps your body to accept the new organ as if it were your own.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Grafishield 0.5 Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Grafishield 0.5 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Grafishield 0.5 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Grafishield 0.5 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Grafishield 0.5 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Grafishield 0.5 Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Grafishield 0.5 Capsule should be used with caution in patients with liver disease. Dose adjustment of Grafishield 0.5 Capsule may be needed. Please consult your doctor.
What if you forget to take Grafishield Capsule?
If you miss a dose of Grafishield 0.5 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Grafishield 0.5 Capsule is used to prevent organ rejection in transplant patients.
- It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
- Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness.
- Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
- Do not stop taking Grafishield 0.5 Capsule without talking to your doctor first.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- Calcineurin inhibitors
Patient concerns
FAQs
Is Grafishield 0.5 Capsule an antibiotic?
Yes, Grafishield 0.5 Capsule is a type of antibiotic which belongs to a group of medicines called macrolides. It is mostly used after organ transplantation. This medicine’s immune-suppressing property helps prevent organ rejection after kidney, heart, or liver transplant.
Which vaccines should not be taken while taking Grafishield 0.5 Capsule?
You should avoid taking any live vaccines (vaccines that use pathogens that are still alive, but are attenuated, that is, weakened) while taking Grafishield 0.5 Capsule. These may include vaccinations for measles, mumps, rubella, BCG (TB vaccine), yellow fever, chicken pox and typhoid. You should also avoid taking polio drops (by mouth) or flu vaccine (through nose).
Who should not take Grafishield 0.5 Capsule?
Patients who are allergic to it or have a weak immune system, high blood pressure, and kidney failure should avoid Grafishield 0.5 Capsule. This medicine should also be avoided in pregnant or breastfeeding women, and in people who plan to receive any live vaccines (e.g. MMR vaccine).
What should I tell my doctor before taking Grafishield 0.5 Capsule?
Inform your doctor if you are pregnant, have allergies, long-term infection, high blood sugar, or high blood pressure. You should also inform your doctor if you have high blood potassium levels or a weakened immune system. Tell your doctor if you have a history of any medication, have recently received, or are scheduled to receive a live vaccine.
What should I be aware of before I start taking Grafishield 0.5 Capsule?
This medicine suppresses the immune system and hence there is always an increased risk of infection. Moreover, in some cases, Grafishield 0.5 Capsule can increase the risk of some kind of cancer like skin and lymph gland cancer (lymphoma). It can lower the ability of your immune system to fight infections. Consult your doctor before you start taking this medication and in case you notice any symptoms of infections like fever, sweats or chills, cough or flu-like symptoms, muscle aches, warm, red, or painful areas on your skin.
Does Grafishield 0.5 Capsule have an abuse potential?
No, Grafishield 0.5 Capsule does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission from authorities and doctors for use.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
- Tacrolimus monohydrate. Camberley, Surrey: Sandoz Limited; 2010 [revised 27 Mar. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
- Tacrolimus. Princeton, New Jersey: Sandoz Inc; 2009. [Accessed 06 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Tacrolimus. [Accessed 06 Aug. 2023]. (online) Available from:
- Tacrolimus [package Insert]. Karapakkam, Chennai: The Madras Pharmaceuticals; 2020. [Accessed 06 Aug. 2023]. (online) Available from:
Marketer details
Name: Deleton Life Sciences Private Limited
Address: ,#325,9TH CROSS,29TH MAIN,SECTOR-1,HSR LAYOUT,BANGLORE-560102 INDIA 9535333007, 080-3586894
Country of origin: India
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MRP
₹195
Inclusive of all taxes
10.0 capsules in 1 strip
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