Glerelin Injection
Prescription Required
Product introduction
Glerelin Injection is used in the treatment of prostate cancer. It is also used to treat endometriosis (endometrium of the uterus grows excessively and causes symptoms like pain, heavy or irregular periods), uterine fibroids and central precocious puberty (very early puberty).
Glerelin Injection is used to treat prostate cancer in men and to aid women in getting pregnant and treat endometriosis in women (condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere)
Glerelin Injection is used to treat prostate cancer in men and to aid women in getting pregnant and treat endometriosis in women (condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere)
Uses of Glerelin Injection
- Treatment of Prostate cancer
- Treatment of Endometriosis
- Treatment of Uterine fibroids
- Treatment of Precocious puberty (premature puberty)
Benefits of Glerelin Injection
In Treatment of Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Glerelin Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
In Treatment of Endometriosis
Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Glerelin Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.
In Treatment of Uterine fibroids
Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Glerelin Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further.
In Treatment of Precocious puberty (premature puberty)
When puberty (change of a child’s body to adult structure and size) begins before age 8 in girls and before age 9 in boys, it is considered precocious puberty. Glerelin Injection helps delay this early onset of adulthood and limits the onset of precocious puberty. However, this medicine is given by a doctor and should not be self-administered. Follow your doctor’s instructions carefully for the most benefit.
Side effects of Glerelin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Glerelin
- Decreased libido
- Testicular atrophy
- Increased sweating
- Fatigue
- Muscle weakness
- Erectile dysfunction
- Bone pain
- Injection site reaction
- Hot flashes
How to use Glerelin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Glerelin Injection. Please consult your doctor.
Pregnancy
UNSAFE
Glerelin Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Glerelin Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Glerelin Injection may cause side effects which could affect your ability to drive.
Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Glerelin Injection.
Do not drive or operate machinery if you experience drowsiness, dizziness or visual disturbances whilst being treated with Glerelin Injection.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Glerelin Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Glerelin Injection in patients with liver disease. Please consult your doctor.
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Quick tips
- Glerelin Injection helps in the treatment of locally advanced or metastatic prostate cancer.
- It may also be used to treat endometriosis and uterine fibroids.
- It is given as an injection either under the skin or into a muscle.
- It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
- It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
- Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
- Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
Fact Box
Chemical Class
GNRH Analogue
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
GNRH agonists/analogue
Patient concerns
User feedback
Patients taking Glerelin Injection
Once A Month
86%
Once A Day
14%
FAQs
Is Glerelin Injection a chemotherapy medicine?
No, Glerelin Injection is not a chemotherapy medicine. Glerelin Injection is a synthetic hormone analogue medicine which is used for the treatment of hormone-dependent conditions in men and women.
Does Glerelin Injection stop periods?
Yes, the periods tend to stop while taking Glerelin Injection injections as this medicine alters the reproductive hormones in females. Sometimes, there can be vaginal bleeding in few cases. If this occurs, please contact your doctor to get yourself assessed and follow the direction of your doctor.
Is Glerelin Injection a hormonal medicine and can it be given in pregnancy?
Yes, Glerelin Injection is a hormonal medicine which alters the reproductive hormones when given in females. This medication is not recommended for use in women who are or may become pregnant because this can harm the fetus in the womb. Using this medicine during pregnancy may also lead to abortion of the baby. Do inform your doctor if you are pregnant or are planning to get pregnant before starting this medication.
Can taking Glerelin Injection affect my bones?
Yes, there are chances of Glerelin Injection affecting your bones. Using Glerelin Injection may cause a decrease in bone mineral density and make the bones weaker. In women, bone density should be assessed before starting the treatment. Special care and monitoring should be done in women with increased risk of osteoporosis. If at all needed, additional medicines may be given to prevent the development of osteoporosis in patients with decreased bone mineral density.
Can Glerelin Injection cause diabetes or increased blood sugar?
Yes, Glerelin Injection may cause an increase in blood sugar levels, worsening the blood glucose control in patients with diabetes. It can even increase the risk of developing diabetes. Therefore, you must monitor the blood glucose and/or glycosylated hemoglobin (HbA1c) from time to time to keep a track of the glucose control and inform your doctor in case you develop any problem. Diabetic patients when prescribed this medication should monitor the sugar levels more frequently while taking this treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 959.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 787-88.
- Leuprorelin acetate. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2011 [revised 11 Jun. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Leuprolide Leuprorelin acetate. Fort Collins: TOLMAR Inc.; 2002 [revised Feb. 2016]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Country of origin: India
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₹13300
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1.0 Injection in 1 vial
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